4OI7
| RAGE recognizes nucleic acids and promotes inflammatory responses to DNA | Descriptor: | 1,2-ETHANEDIOL, 5'-D(*CP*AP*CP*GP*TP*TP*CP*GP*TP*AP*GP*CP*AP*TP*CP*GP*TP*TP*GP*CP*AP*G)-3', 5'-D(*CP*TP*GP*CP*AP*AP*CP*GP*AP*TP*GP*CP*TP*AP*CP*GP*AP*AP*CP*GP*TP*G)-3', ... | Authors: | Jin, T, Jiang, J, Xiao, T. | Deposit date: | 2014-01-19 | Release date: | 2014-04-30 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (3.104 Å) | Cite: | RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA. J.Exp.Med., 210, 2013
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4OI8
| RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA. | Descriptor: | 5'-D(*CP*CP*AP*TP*GP*AP*CP*TP*GP*TP*AP*GP*GP*AP*AP*AP*CP*TP*CP*TP*AP*GP*A)-3', 5'-D(*CP*TP*CP*TP*AP*GP*AP*GP*TP*TP*TP*CP*CP*TP*AP*CP*AP*GP*TP*CP*AP*TP*G)-3', Advanced glycosylation end product-specific receptor | Authors: | Jin, T, Jiang, J, Xiao, T. | Deposit date: | 2014-01-19 | Release date: | 2014-04-30 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (3.101 Å) | Cite: | RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA. J.Exp.Med., 210, 2013
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4EO7
| Crystal structure of the TIR domain of human myeloid differentiation primary response protein 88. | Descriptor: | MAGNESIUM ION, Myeloid differentiation primary response protein MyD88 | Authors: | Snyder, G.A, Cirl, C, Jiang, J.S, Chen, P, Smith, T, Xiao, T.S. | Deposit date: | 2012-04-13 | Release date: | 2013-04-10 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.449 Å) | Cite: | Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli. Proc.Natl.Acad.Sci.USA, 110, 2013
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3UM0
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3UM3
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3UM1
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3UM2
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3ULY
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2R77
| Crystal structure of phosphatidylethanolamine-binding protein, pfl0955c, from Plasmodium falciparum | Descriptor: | Phosphatidylethanolamine-binding protein, putative | Authors: | Wernimont, A.K, Lew, J, Kozieradzki, I, Lin, Y.H, Sun, X, Khuu, C, Crombette, L, Zhao, Y, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Artz, J.D, Xiao, T, Structural Genomics Consortium (SGC) | Deposit date: | 2007-09-07 | Release date: | 2007-09-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of phosphatidylethanolamine-binding protein, pfl0955c, from Plasmodium falciparum. To be Published
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3VD8
| Crystal structure of human AIM2 PYD domain with MBP fusion | Descriptor: | 1,2-ETHANEDIOL, Maltose-binding periplasmic protein, Interferon-inducible protein AIM2, ... | Authors: | Jin, T.C, Perry, A, Smith, P, Xiao, T.S. | Deposit date: | 2012-01-04 | Release date: | 2013-01-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.0685 Å) | Cite: | Structure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome Assembly. J.Biol.Chem., 288, 2013
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4IFP
| X-ray Crystal Structure of Human NLRP1 CARD Domain | Descriptor: | MALONATE ION, Maltose-binding periplasmic protein,NACHT, LRR and PYD domains-containing protein 1, ... | Authors: | Jin, T, Curry, J, Smith, P, Jiang, J, Xiao, T. | Deposit date: | 2012-12-14 | Release date: | 2013-04-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9948 Å) | Cite: | Structure of the NLRP1 caspase recruitment domain suggests potential mechanisms for its association with procaspase-1. Proteins, 81, 2013
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4IKM
| X-ray structure of CARD8 CARD domain | Descriptor: | 1,2-ETHANEDIOL, IODIDE ION, Maltose-binding periplasmic protein, ... | Authors: | Jin, T, Huang, M, Smith, P, Jiang, J, Xiao, T. | Deposit date: | 2012-12-26 | Release date: | 2013-05-08 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.4606 Å) | Cite: | The structure of the CARD8 caspase-recruitment domain suggests its association with the FIIND domain and procaspases through adjacent surfaces. Acta Crystallogr.,Sect.F, 69, 2013
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4IRL
| X-ray structure of the CARD domain of zebrafish GBP-NLRP1 like protein | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Jin, T, Huang, M, Smith, P, Xiao, T. | Deposit date: | 2013-01-15 | Release date: | 2013-08-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Structure of the caspase-recruitment domain from a zebrafish guanylate-binding protein. Acta Crystallogr.,Sect.F, 69, 2013
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4QLC
| Crystal structure of chromatosome at 3.5 angstrom resolution | Descriptor: | CITRIC ACID, DNA (167-mer), H5, ... | Authors: | Jiang, J.S, Zhou, B.R, Xiao, T.S, Bai, Y.W. | Deposit date: | 2014-06-11 | Release date: | 2015-07-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.503 Å) | Cite: | Structural Mechanisms of Nucleosome Recognition by Linker Histones. Mol.Cell, 33 Suppl 1, 2015
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4LQC
| The crystal structures of the Brucella protein TcpB and the TLR adaptor protein TIRAP show structural differences in microbial TIR mimicry. | Descriptor: | TcpB | Authors: | Snyder, G.A, Smith, P, Fresquez, T, Cirl, C, Jiang, J, Snyder, N, Luchetti, T, Miethke, T, Xiao, T.S. | Deposit date: | 2013-07-17 | Release date: | 2013-12-04 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of the Toll/Interleukin-1 receptor (TIR) domains from the Brucella protein TcpB and host adaptor TIRAP reveal mechanisms of molecular mimicry. J.Biol.Chem., 289, 2014
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4LQD
| The crystal structures of the Brucella protein TcpB and the TLR adaptor protein TIRAP show structural differences in microbial TIR mimicry | Descriptor: | GLYCEROL, Toll/interleukin-1 receptor domain-containing adapter protein | Authors: | Snyder, G.A, Smith, P, Jiang, J, Xiao, T.S. | Deposit date: | 2013-07-17 | Release date: | 2013-12-04 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.451 Å) | Cite: | Crystal structures of the Toll/Interleukin-1 receptor (TIR) domains from the Brucella protein TcpB and host adaptor TIRAP reveal mechanisms of molecular mimicry. J.Biol.Chem., 289, 2014
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5Y3S
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5Z7D
| p204HINab-dsDNA complex structure | Descriptor: | DNA (5'-D(P*CP*CP*AP*TP*CP*AP*GP*AP*AP*AP*GP*AP*GP*AP*GP*C)-3'), Interferon-activable protein 204 | Authors: | Jin, T, Jiang, J, Xiao, T.S. | Deposit date: | 2018-01-28 | Release date: | 2019-01-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | Structural mechanism of DNA recognition by the p204 HIN domain. Nucleic Acids Res., 2021
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4M6B
| Crystal structure of yeast Swr1-Z domain in complex with H2A.Z-H2B dimer | Descriptor: | Chimera protein of Histone H2B.1 and Histone H2A.Z, Helicase SWR1 | Authors: | Hong, J.J, Feng, H.Q, Wang, F, Ranjan, A, Chen, J.H, Jiang, J.S, Girlando, R, Xiao, T.S, Wu, C, Bai, Y.W. | Deposit date: | 2013-08-09 | Release date: | 2014-02-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | The Catalytic Subunit of the SWR1 Remodeler Is a Histone Chaperone for the H2A.Z-H2B Dimer. Mol.Cell, 53, 2014
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3KU2
| Crystal Structure of inactivated form of CDPK1 from toxoplasma gondii, TGME49.101440 | Descriptor: | Calmodulin-domain protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, UNKNOWN ATOM OR ION | Authors: | Wernimont, A.K, Artz, J.D, Finnerty, P, Xiao, T, He, H, Mackenzie, F, Sinestera, G, Hassani, A.A, Wasney, G, Vedadi, M, Lourido, S, Bochkarev, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Sibley, D.L, Hui, R, Lin, Y.H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-11-26 | Release date: | 2010-02-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium. Nat.Struct.Mol.Biol., 17, 2010
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5XIV
| Beta-Ginkgotides: Hyperdisulfide-constrained peptides from Ginkgo biloba | Descriptor: | beta-ginkgotide, beta-gB1 | Authors: | Wong, K.H, Tan, W.L, Xiao, T, Tam, J.P. | Deposit date: | 2017-04-27 | Release date: | 2017-05-31 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | beta-Ginkgotides: Hyperdisulfide-constrained peptides from Ginkgo biloba. Sci Rep, 7, 2017
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6AO4
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3HX4
| Crystal structure of CDPK1 of Toxoplasma gondii, TGME49_101440, in presence of calcium | Descriptor: | CALCIUM ION, Calmodulin-domain protein kinase 1, GLYCEROL, ... | Authors: | Wernimont, A.K, Artz, J.D, Finnerty, P, Xiao, T, He, H, MacKenzie, F, Sinestera, G, Hassani, A.A, Wasney, G, Vedadi, M, Lourido, S, Bochkarev, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Sibley, D.L, Hui, R, Lin, Y.H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-06-19 | Release date: | 2009-07-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium. Nat.Struct.Mol.Biol., 17, 2010
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5ZX1
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4NKG
| Crystal structure of SspH1 LRR domain in complex PKN1 HR1b domain | Descriptor: | E3 ubiquitin-protein ligase sspH1, HEXANE-1,6-DIOL, Serine/threonine-protein kinase N1 | Authors: | Keszei, A.F.A, Xiaojing, T, Mccormick, C, Zeqiraj, E, Rohde, J.R, Tyers, M, Sicheri, F. | Deposit date: | 2013-11-12 | Release date: | 2013-12-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of an SspH1-PKN1 Complex Reveals the Basis for Host Substrate Recognition and Mechanism of Activation for a Bacterial E3 Ubiquitin Ligase. Mol.Cell.Biol., 34, 2014
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