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PDB: 288 件

6JMU
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Crystal structure of GIT1/Paxillin complex
分子名称: ARF GTPase-activating protein GIT1, Paxillin
著者Zhu, J, Lin, L, Xia, Y, Zhang, R, Zhang, M.
登録日2019-03-13
公開日2020-05-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献GIT/PIX Condensates Are Modular and Ideal for Distinct Compartmentalized Cell Signaling.
Mol.Cell, 79, 2020
7YIV
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BU of 7yiv by Molmil
The Crystal Structure of Human Tissue Nonspecific Alkaline Phosphatase (ALPL) at Basic pH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alkaline phosphatase, ...
著者Cao, Y, Qin, A, Yu, Y.T, Yao, D.Q, Zhang, Q, Rao, B, Xia, Y, Lu, Y.
登録日2022-07-18
公開日2023-07-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献The structural pathology for hypophosphatasia caused by malfunctional tissue non-specific alkaline phosphatase.
Nat Commun, 14, 2023
7YIW
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The Crystal Structure of Human Tissue Nonspecific Alkaline Phosphatase (ALPL) at Acidic pH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alkaline phosphatase, ...
著者Yu, Y.T, Yao, D.Q, Zhang, Q, Rao, B, Xia, Y, Lu, Y, Qin, A, Cao, Y.
登録日2022-07-18
公開日2023-07-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献The structural pathology for hypophosphatasia caused by malfunctional tissue non-specific alkaline phosphatase.
Nat Commun, 14, 2023
7YIX
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The Cryo-EM Structure of Human Tissue Nonspecific Alkaline Phosphatase and Single-Chain Fragment Variable (ScFv) Complex.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alkaline phosphatase, ...
著者Yu, Y.T, Yao, D.Q, Zhang, Q, Rao, B, Xia, Y, Lu, Y, Qin, A, Ma, P.X, Cao, Y.
登録日2022-07-18
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (2.96 Å)
主引用文献The structural pathology for hypophosphatasia caused by malfunctional tissue non-specific alkaline phosphatase.
Nat Commun, 14, 2023
7Y53
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The cryo-EM structure of human ERAD retro-translocation complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Derlin-1, Transitional endoplasmic reticulum ATPase
著者Cao, Y, Rao, B, Wang, Q, Yao, D, Xia, Y, Li, W, Li, S, Shen, Y.
登録日2022-06-16
公開日2023-10-18
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.61 Å)
主引用文献The cryo-EM structure of the human ERAD retrotranslocation complex.
Sci Adv, 9, 2023
7Y59
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The cryo-EM structure of human ERAD retro-translocation complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Derlin-1, ...
著者Cao, Y, Rao, B, Wang, Q, Yao, D, Xia, Y, Li, W, Li, S, Shen, Y.
登録日2022-06-16
公開日2023-10-18
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (4.51 Å)
主引用文献The cryo-EM structure of the human ERAD retrotranslocation complex.
Sci Adv, 9, 2023
7Y4W
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The cryo-EM structure of human ERAD retro-translocation complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Derlin-1, Transitional endoplasmic reticulum ATPase
著者Cao, Y, Rao, B, Wang, Q, Yao, D, Xia, Y, Li, W, Li, S, Shen, Y.
登録日2022-06-16
公開日2023-10-18
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献The cryo-EM structure of the human ERAD retrotranslocation complex.
Sci Adv, 9, 2023
7CZB
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The cryo-EM structure of the ERAD retrotranslocation channel formed by human Derlin-1
分子名称: Derlin-1
著者Rao, B, Li, S, Yao, D, Wang, Q, Xia, Y, Jia, Y, Shen, Y, Cao, Y.
登録日2020-09-07
公開日2021-03-17
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献The cryo-EM structure of an ERAD protein channel formed by tetrameric human Derlin-1.
Sci Adv, 7, 2021
7F3X
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Lysophospholipid acyltransferase LPCAT3 in complex with lysophosphatidylcholine
分子名称: LPCAT3, [2-((1-OXODODECANOXY-(2-HYDROXY-3-PROPANYL))-PHOSPHONATE-OXY)-ETHYL]-TRIMETHYLAMMONIUM
著者Zhang, Q, Yao, D, Rao, B, Li, S, Jian, L, Chen, Y, Hu, K, Xia, Y, Shen, Y, Cao, Y.
登録日2021-06-17
公開日2021-12-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3.
Nat Commun, 12, 2021
7EWT
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The crystal structure of Lysophospholipid acyltransferase LPCAT3 (MOBAT5) in its monomeric and apo form
分子名称: Lysophospholipid acyltransferase 5
著者Zhang, Q, Yao, D, Rao, B, Li, S, Jian, L, Chen, Y, Hu, K, Xia, Y, Cao, Y.
登録日2021-05-26
公開日2021-12-01
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3.
Nat Commun, 12, 2021
7F40
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Lysophospholipid acyltransferase LPCAT3 in a complex with Arachidonoyl-CoA
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, LPCAT3, S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenethioate
著者Zhang, Q, Yao, D, Rao, B, Li, S, Jian, L, Chen, Y, Hu, K, Xia, Y, Shen, Y, Cao, Y.
登録日2021-06-17
公開日2021-12-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3.
Nat Commun, 12, 2021
5CYW
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BU of 5cyw by Molmil
Crystal Structure of Vaccinia Virus C7
分子名称: GLYCEROL, Interferon antagonist C7
著者Krumm, B.E, Meng, X, Li, Y, Xiang, Y, Deng, J.
登録日2015-07-30
公開日2015-11-18
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for antagonizing a host restriction factor by C7 family of poxvirus host-range proteins.
Proc.Natl.Acad.Sci.USA, 112, 2015
5CZ3
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Crystal Structure of Myxoma Virus M64
分子名称: BETA-MERCAPTOETHANOL, M64R
著者Krumm, B.E, Meng, X, Li, Y, Xiang, Y, Deng, J.
登録日2015-07-31
公開日2015-11-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for antagonizing a host restriction factor by C7 family of poxvirus host-range proteins.
Proc.Natl.Acad.Sci.USA, 112, 2015
4W60
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BU of 4w60 by Molmil
The structure of Vaccina virus H7 protein displays A Novel Phosphoinositide binding fold required for membrane biogenesis
分子名称: Late protein H7
著者Kolli, S, Meng, X, Wu, X, Shengjuler, D, Cameron, C.E, Xiang, Y, Deng, J.
登録日2014-08-19
公開日2014-12-31
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure-function analysis of vaccinia virus h7 protein reveals a novel phosphoinositide binding fold essential for poxvirus replication.
J.Virol., 89, 2015
1T0Z
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BU of 1t0z by Molmil
Structure of an Excitatory Insect-specific Toxin with an Analgesic Effect on Mammalian from Scorpion Buthus martensii Karsch
分子名称: SULFATE ION, insect neurotoxin
著者Li, C, Guan, R.-J, Xiang, Y, Zhang, Y, Wang, D.-C.
登録日2004-04-14
公開日2004-12-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of an excitatory insect-specific toxin with an analgesic effect on mammals from the scorpion Buthus martensii Karsch.
Acta Crystallogr.,Sect.D, 61, 2005
2ISO
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Ternary complex of DNA Polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-difluoromethylene triphosphate
分子名称: 2'-DEOXY-5'-O-[({[DIFLUORO(PHOSPHONO)METHYL](HYDROXY)PHOSPHORYL}OXY)(HYDROXY)PHOSPHORYL]GUANOSINE, 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', ...
著者Sucato, C.A, Upton, T.G, Kashemirov, B.A, Martinek, V, Xiang, Y, Beard, W.A.
登録日2006-10-18
公開日2007-01-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Modifying the beta,gamma Leaving-Group Bridging Oxygen Alters Nucleotide Incorporation Efficiency, Fidelity, and the Catalytic Mechanism of DNA Polymerase beta.
Biochemistry, 46, 2007
6OZB
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BU of 6ozb by Molmil
Crystal structure of the phycoerythrobilin-bound GAF domain from a cyanobacterial phytochrome
分子名称: PHYCOERYTHROBILIN, Two-component sensor histidine kinase
著者Heewhan, S, Xiaoli, Z, Yafang, S, Zhong, R, Wolfgang, G, Kai, H.Z, Xiaojing, Y.
登録日2019-05-15
公開日2020-05-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The interplay between chromophore and protein determines the extended excited state dynamics in a single-domain phytochrome.
Proc.Natl.Acad.Sci.USA, 117, 2020
6OZA
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Crystal structure of the phycocyanobilin-bound GAF domain from a cyanobacterial phytochrome
分子名称: PHYCOCYANOBILIN, Two-component sensor histidine kinase
著者Heewhan, S, Xiaoli, Z, Yafang, S, Zhong, R, Wolfgang, G, Kai, H.Z, Xiaojing, Y.
登録日2019-05-15
公開日2020-05-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.002 Å)
主引用文献The interplay between chromophore and protein determines the extended excited state dynamics in a single-domain phytochrome.
Proc.Natl.Acad.Sci.USA, 117, 2020
5KIJ
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Crystal structure of the class I human endoplasmic reticulum 1,2-alpha-mannosidase and Man9GlcNAc2-PA complex
分子名称: 1,4-BUTANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, ...
著者Karaveg, K, Xiang, Y, Moremen, K.W.
登録日2016-06-16
公開日2017-05-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.649 Å)
主引用文献Substrate recognition and catalysis by GH47 alpha-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5KK7
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Crystal structure of the class I human endoplasmic reticulum 1,2-alpha-mannosidase T688A mutant and Thio-disaccharide substrate analog complex
分子名称: 1,4-BUTANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, ACETATE ION, ...
著者Karaveg, K, Xiang, Y, Moremen, K.W.
登録日2016-06-21
公開日2017-05-10
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.7324 Å)
主引用文献Substrate recognition and catalysis by GH47 alpha-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
4U03
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BU of 4u03 by Molmil
Structure of the vibrio cholerae di-nucleotide cyclase (DncV) in complex with GTP and 5MTHFGLU2
分子名称: Cyclic AMP-GMP synthase, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Zhu, D.Y, Xiang, Y.
登録日2014-07-11
公開日2014-09-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.041 Å)
主引用文献Structural Biochemistry of a Vibrio cholerae Dinucleotide Cyclase Reveals Cyclase Activity Regulation by Folates.
Mol.Cell, 55, 2014
4U0M
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Structure of the Vibrio cholerae di-nucleotide cyclase (DncV) mutant D193N in complex with ATP, GTP and 5MTHFGLU2
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic AMP-GMP synthase, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Zhu, D, Xiang, Y.
登録日2014-07-12
公開日2014-09-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Biochemistry of a Vibrio cholerae Dinucleotide Cyclase Reveals Cyclase Activity Regulation by Folates.
Mol.Cell, 55, 2014
4YJE
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Crystal structure of APC-ARM in complexed with Amer1-A1
分子名称: APC membrane recruitment protein 1, Adenomatous polyposis coli protein
著者Zhang, Z, Xiao, Y, Wu, G.
登録日2015-03-03
公開日2016-03-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners
Cell Discov, 1, 2015
4YJL
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Crystal structure of APC-ARM in complexed with Amer1-A2
分子名称: 1,2-ETHANEDIOL, APC membrane recruitment protein 1, Adenomatous polyposis coli protein
著者Zhang, Z, Xiao, Y, Wu, G.
登録日2015-03-03
公開日2016-03-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners
Cell Discov, 1, 2015
1P9Z
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The Solution Structure of Antifungal Peptide Distinct With a Five-disulfide Motif from Eucommia ulmoides Oliver
分子名称: Eucommia Antifungal peptide 2
著者Huang, R.H, Xiang, Y, Tu, G.Z, Zhang, Y, Wang, D.C.
登録日2003-05-13
公開日2004-05-25
最終更新日2019-12-25
実験手法SOLUTION NMR
主引用文献Solution Structure of Eucommia Antifungal Peptide: A Novel Structural Model Distinct with a Five-Disulfide Motif.
Biochemistry, 43, 2004

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