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PDB: 12 件

2BC4
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Crystal structure of HLA-DM
分子名称: CHLORIDE ION, HLA class II histocompatibility antigen, DM alpha chain, ...
著者Nicholson, M.J, Moradi, B, Seth, N.P, Xing, X, Cuny, G.D, Stein, R.L, Wucherpfennig, K.W.
登録日2005-10-18
公開日2006-05-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Small molecules that enhance the catalytic efficiency of HLA-DM.
J.Immunol., 176, 2006
3PL6
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Structure of Autoimmune TCR Hy.1B11 in complex with HLA-DQ1 and MBP 85-99
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MBP peptide / T-cell receptor beta chain chimera, MHC class II HLA-DQ-alpha chain, ...
著者Sethi, D.K, Wucherpfennig, K.W.
登録日2010-11-13
公開日2010-12-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC.
J.Exp.Med., 208, 2011
1JK8
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Crystal structure of a human insulin peptide-HLA-DQ8 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II HLA-DQ8, insulin B peptide
著者Lee, K.H, Wucherpfennig, K.W, Wiley, D.C.
登録日2001-07-11
公開日2001-08-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetes.
Nat.Immunol., 2, 2001
2HAC
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Structure of Zeta-Zeta Transmembrane Dimer
分子名称: T-cell surface glycoprotein CD3 zeta chain
著者Chou, J.J, Wucherpfennig, K.W, Schnell, J.R, Call, M.E.
登録日2006-06-12
公開日2006-10-31
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献The structure of the zetazeta transmembrane dimer reveals features essential for its assembly with the T cell receptor.
Cell(Cambridge,Mass.), 127, 2006
2K4F
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Mouse CD3epsilon Cytoplasmic Tail
分子名称: T-cell surface glycoprotein CD3 epsilon chain
著者Xu, C, Call, M.E, Schwieters, C.D, Schnell, J.R, Gagnon, E.E, Wucherpfennig, K.W, Chou, J.J.
登録日2008-06-07
公開日2008-12-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3varepsilon Cytoplasmic Tyrosine-Based Motif.
Cell(Cambridge,Mass.), 135, 2008
4MAY
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Crystal structure of an immune complex
分子名称: HY.1B11 TCR alpha chain, MHC class II HLA-DQ-alpha chain, MHC class II antigen, ...
著者Sethi, D.K, Wucherpfennig, K.W.
登録日2013-08-18
公開日2013-10-23
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crossreactivity of a human autoimmune TCR is dominated by a single TCR loop.
Nat Commun, 4, 2013
1YMM
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TCR/HLA-DR2b/MBP-peptide complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ...
著者Hahn, M, Nicholson, M.J, Pyrdol, J, Wucherpfennig, K.W.
登録日2005-01-21
公開日2005-05-03
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Unconventional topology of self peptide-major histocompatibility complex binding by a human autoimmune T cell receptor.
NAT.IMMUNOL., 6, 2005
2L35
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Structure of the DAP12-NKG2C transmembrane heterotrimer
分子名称: DAP12-NKG2C_TM, TYRO protein tyrosine kinase-binding protein
著者Call, M.E, Wucherpfennig, K.W, Chou, J.J.
登録日2010-09-06
公開日2010-11-03
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The structural basis for intramembrane assembly of an activating immunoreceptor complex.
Nat.Immunol., 11, 2010
2L34
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Structure of the DAP12 transmembrane homodimer
分子名称: TYRO protein tyrosine kinase-binding protein
著者Call, M.E, Wucherpfennig, K.W, Chou, J.J.
登録日2010-09-06
公開日2010-11-03
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The structural basis for intramembrane assembly of an activating immunoreceptor complex.
Nat.Immunol., 11, 2010
4FQX
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Crystal structure of HLA-DM bound to HLA-DR1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DM alpha chain, ...
著者Sethi, D.K, Pos, W, Wucherpfennig, K.W.
登録日2012-06-25
公開日2013-01-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.599 Å)
主引用文献Crystal Structure of the HLA-DM-HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection.
Cell(Cambridge,Mass.), 151, 2012
4GBX
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Crystal structure of an immune complex at pH 6.5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DM alpha chain, ...
著者Sethi, D.K, Pos, W, Wucherpfennig, K.W.
登録日2012-07-28
公開日2013-01-16
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structure of the HLA-DM-HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection.
Cell(Cambridge,Mass.), 151, 2012
4GRL
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Crystal structure of a autoimmune TCR-MHC complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II HLA-DQ-alpha chain, MHC class II antigen, ...
著者Sethi, D.K, Wucherpfennig, K.W.
登録日2012-08-25
公開日2013-11-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Crossreactivity of a human autoimmune TCR is dominated by a single TCR loop.
Nat Commun, 4, 2013

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件を2024-06-19に公開中

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