2BC4

Crystal structure of HLA-DM

Summary for 2BC4

Entry DOI	10.2210/pdb2bc4/pdb
Descriptor	HLA class II histocompatibility antigen, DM alpha chain, HLA class II histocompatibility antigen, DM beta chain, beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	mhc class ii, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	96786.24
Authors	Nicholson, M.J.,Moradi, B.,Seth, N.P.,Xing, X.,Cuny, G.D.,Stein, R.L.,Wucherpfennig, K.W. (deposition date: 2005-10-18, release date: 2006-05-23, Last modification date: 2023-09-20)
Primary citation	Nicholson, M.J.,Moradi, B.,Seth, N.P.,Xing, X.,Cuny, G.D.,Stein, R.L.,Wucherpfennig, K.W. Small molecules that enhance the catalytic efficiency of HLA-DM. J.Immunol., 176:4208-4220, 2006 Cited by PubMed: 16547258 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.27 Å)

Structure validation