2K4F

Mouse CD3epsilon Cytoplasmic Tail

Summary for 2K4F

Entry DOI	10.2210/pdb2k4f/pdb
Descriptor	T-cell surface glycoprotein CD3 epsilon chain (1 entity in total)
Functional Keywords	itam, tcr, cd3e, membrane bound protein, bicelle, immunoglobulin domain, membrane, phosphoprotein, receptor, transmembrane, immune system, signaling protein
Biological source	Mus musculus (mouse)
Cellular location	Membrane; Single-pass type I membrane protein: P22646
Total number of polymer chains	1
Total formula weight	6313.18
Authors	Xu, C.,Call, M.E.,Schwieters, C.D.,Schnell, J.R.,Gagnon, E.E.,Wucherpfennig, K.W.,Chou, J.J. (deposition date: 2008-06-07, release date: 2008-12-02, Last modification date: 2022-03-16)
Primary citation	Xu, C.,Gagnon, E.,Call, M.E.,Schnell, J.R.,Schwieters, C.D.,Carman, C.V.,Chou, J.J.,Wucherpfennig, K.W. Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3varepsilon Cytoplasmic Tyrosine-Based Motif. Cell(Cambridge,Mass.), 135:702-713, 2008 Cited by PubMed: 19013279 DOI: 10.1016/j.cell.2008.09.044 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation