2K4F

Mouse CD3epsilon Cytoplasmic Tail

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0007166	biological_process	cell surface receptor signaling pathway
A	0016020	cellular_component	membrane

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	54
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	27
Details	Domain: {"description":"ITAM","evidences":[{"source":"PROSITE-ProRule","id":"PRU00379","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	46
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	17
Details	Region: {"description":"NUMB-binding region","evidences":[{"source":"UniProtKB","id":"P07766","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	7
Details	Region: {"description":"Proline-rich sequence","evidences":[{"source":"UniProtKB","id":"P07766","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P07766","evidenceCode":"ECO:0000250"},{"source":"PROSITE-ProRule","id":"PRU00379","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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