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1YMM

TCR/HLA-DR2b/MBP-peptide complex

Summary for 1YMM
Entry DOI10.2210/pdb1ymm/pdb
DescriptorHLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DR beta chain, MBP peptide, ... (6 entities in total)
Functional Keywordsprotein-protein complex, t cell repertoire, auto-immunity, immune system
Biological sourceHomo sapiens (human)
More
Cellular locationCell membrane; Single-pass type I membrane protein: P01903
Myelin membrane; Peripheral membrane protein; Cytoplasmic side: P02686
Membrane; Single-pass membrane protein (Potential): P01850
Total number of polymer chains5
Total formula weight98519.68
Authors
Hahn, M.,Nicholson, M.J.,Pyrdol, J.,Wucherpfennig, K.W. (deposition date: 2005-01-21, release date: 2005-05-03, Last modification date: 2021-10-20)
Primary citationHahn, M.,Nicholson, M.J.,Pyrdol, J.,Wucherpfennig, K.W.
Unconventional topology of self peptide-major histocompatibility complex binding by a human autoimmune T cell receptor.
NAT.IMMUNOL., 6:490-496, 2005
Cited by
PubMed: 15821740
DOI: 10.1038/ni1187
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.5 Å)
Structure validation

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