1YMM
TCR/HLA-DR2b/MBP-peptide complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | HLA class II histocompatibility antigen, DR alpha chain | polymer | 191 | 22107.9 | 1 | UniProt (P01903) Pfam (PF00993) Pfam (PF07654) In PDB | Homo sapiens (human) | HLA-DR2b alpha |
2 | B | HLA class II histocompatibility antigen, DR beta chain | polymer | 198 | 22991.6 | 1 | UniProt (Q29790) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01911) In PDB | Homo sapiens (human) | HLA-DR2b beta |
3 | C | MBP peptide | polymer | 23 | 2286.5 | 1 | UniProt (P02686) In PDB | ||
4 | D | T cell receptor alpha chain | polymer | 207 | 22978.3 | 1 | GenBank (29293741) Pfam (PF09291) UniProt (by SIFTS) (P01848) In PDB | Homo sapiens (human) | TCR Ob.1A12 alpha |
5 | E | T-cell receptor beta chain | polymer | 249 | 27934.1 | 1 | UniProt (P01850) Pfam (PF07654) In PDB | Homo sapiens (human) | TCR Ob.1A12 beta |
6 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
D: 1 - 207 (GenBank: 29293741)
E: 1 - 249 (UniProt: P01850)
PDB | External Database | Details |
---|---|---|
Asp 92 | Ala 112 | see remark 999 |
Thr 93 | Asn 113 | see remark 999 |
Thr 94 | Ala 114 | see remark 999 |
Ser 95 | Gly 115 | see remark 999 |
- | Ser 118 | see remark 999 |
- | Gly 120 | see remark 999 |
Tyr 100 | Leu 122 | see remark 999 |
Ile 101 | Thr 123 | see remark 999 |
Thr 104 | Gln 126 | see remark 999 |
Arg 107 | Ile 129 | see remark 999 |
Lys 109 | Thr 131 | see remark 999 |
Leu 111 | His 133 | see remark 999 |
Ala 112 | Pro 134 | see remark 999 |
PDB | External Database | Details |
---|---|---|
Ser 13 | Cys 28 | engineered mutation |
Asp 98 | Glu 113 | see remark 999 |
Leu 99 | Ser 114 | see remark 999 |
Gly 102 | Asp 117 | see remark 999 |
Ala 103 | Pro 118 | see remark 999 |
Asn 104 | Lys 119 | see remark 999 |
Ser 193 | Cys 208 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 98298.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 221.2 | |
All* | Total formula weight | 98519.7 |