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PDB: 597 件
5DOK
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Crystal structure of Tetrahymena p45C
分子名称: MAGNESIUM ION, Telomerase associated protein p45
著者Wan, B, Tang, T, Wu, J, Lei, M.
登録日2015-09-11
公開日2015-11-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Tetrahymena telomerase p75-p45-p19 subcomplex is a unique CST complex
Nat.Struct.Mol.Biol., 22, 2015
5FO7
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BU of 5fo7 by Molmil
Crystal Structure of Human Complement C3b at 2.8 Angstrom resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN
著者Forneris, F, Wu, J, Xue, X, Gros, P.
登録日2015-11-18
公開日2016-04-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
7JU5
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BU of 7ju5 by Molmil
Structure of RET protein tyrosine kinase in complex with pralsetinib
分子名称: FORMIC ACID, Pralsetinib, Proto-oncogene tyrosine-protein kinase receptor Ret
著者Terzyan, S.S, Shen, T, Wu, J, Mooers, B.H.M.
登録日2020-08-19
公開日2020-11-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of acquired resistance to selpercatinib and pralsetinib mediated by non-gatekeeper RET mutations.
Ann Oncol, 32, 2021
4ZMK
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Crystal structure of the dimerization domain of S. pombe Taz1
分子名称: Telomere length regulator taz1
著者Deng, W, Wu, J, Wang, F, Lei, M.
登録日2015-05-04
公開日2015-09-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Fission yeast telomere-binding protein Taz1 is a functional but not a structural counterpart of human TRF1 and TRF2.
Cell Res., 25, 2015
5DOI
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BU of 5doi by Molmil
Crystal structure of Tetrahymena p45N and p19
分子名称: Telomerase associated protein p45, Telomerase-associated protein 19
著者Wan, B, Tang, T, Wu, J, Lei, M.
登録日2015-09-11
公開日2015-11-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Tetrahymena telomerase p75-p45-p19 subcomplex is a unique CST complex
Nat.Struct.Mol.Biol., 22, 2015
5DOF
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Crystal structure of Tetrahymena p19
分子名称: Telomerase-associated protein 19
著者Wan, B, Tang, T, Wu, J, Lei, M.
登録日2015-09-11
公開日2015-11-25
最終更新日2015-12-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Tetrahymena telomerase p75-p45-p19 subcomplex is a unique CST complex.
Nat.Struct.Mol.Biol., 22, 2015
6N3I
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BU of 6n3i by Molmil
Crystal structure of a double Trp XylE mutants (G58W/L315W)
分子名称: D-xylose transporter
著者Jiang, X, Wu, J.P, Yan, N.
登録日2018-11-15
公開日2019-03-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.69 Å)
主引用文献Engineered XylE as a tool for mechanistic investigation and ligand discovery of the glucose transporters GLUTs.
Cell Discov, 5, 2019
5FO9
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Crystal Structure of Human Complement C3b in Complex with CR1 (CCP15- 17)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN, ...
著者Forneris, F, Wu, J, Xue, X, Gros, P.
登録日2015-11-18
公開日2016-04-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
1TP7
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Crystal Structure of the RNA-dependent RNA Polymerase from Human Rhinovirus 16
分子名称: 3-[BENZYL(DIMETHYL)AMMONIO]PROPANE-1-SULFONATE, Genome polyprotein, SULFATE ION
著者Appleby, T.C, Luecke, H, Shim, J.H, Wu, J.Z, Cheney, I.W, Zhong, W, Vogeley, L, Hong, Z, Yao, N.
登録日2004-06-15
公開日2005-06-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of complete rhinovirus RNA polymerase suggests front loading of protein primer.
J.Virol., 79, 2005
1PSQ
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Structure of a probable thiol peroxidase from Streptococcus pneumoniae
分子名称: probable thiol peroxidase
著者Kniewel, R, Buglino, J, Solorzano, V, Wu, J, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2003-06-21
公開日2003-07-08
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of a probable thiol peroxidase from Streptococcus pneumoniae
To be Published
2AIN
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BU of 2ain by Molmil
Solution structure of the AF-6 PDZ domain complexed with the C-terminal peptide from the Bcr protein
分子名称: 6-mer peptide from Breakpoint cluster region protein, Afadin
著者Chen, Q, Wu, J, Shi, Y.
登録日2005-07-30
公開日2006-07-18
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure and backbone dynamics of the AF-6 PDZ domain/Bcr peptide complex.
Protein Sci., 16, 2007
5GRS
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Complex structure of the fission yeast SREBP-SCAP binding domains
分子名称: Sterol regulatory element-binding protein 1, Sterol regulatory element-binding protein cleavage-activating protein
著者Gong, X, Qian, H.W, Wu, J.P, Yan, N.
登録日2016-08-12
公開日2016-12-14
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (5.4 Å)
主引用文献Complex structure of the fission yeast SREBP-SCAP binding domains reveals an oligomeric organization
Cell Res., 26, 2016
1Q98
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Structure of a Thiol Peroxidase from Haemophilus influenzae Rd
分子名称: Thiol Peroxidase
著者Kniewel, R, Buglino, J, Solorzano, V, Wu, J, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2003-08-22
公開日2003-09-09
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of a Thiol Peroxidase from Haemophilus influenzae Rd
To be Published
1PSW
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Structure of E. coli ADP-heptose lps heptosyltransferase II
分子名称: ADP-HEPTOSE LPS HEPTOSYLTRANSFERASE II
著者Kniewel, R, Buglino, J, Solorzano, V, Wu, J, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2003-06-21
公開日2003-07-08
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of E. coli ADP-heptose lps heptosyltransferase II
To be Published
4F2L
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BU of 4f2l by Molmil
Structure of a regulatory domain of AMPK
分子名称: 5'-AMP-activated protein kinase catalytic subunit alpha-1, MAGNESIUM ION
著者Xin, F.J, Zhang, Y.Y, Wang, J, Wang, Z.X, Wu, J.W.
登録日2012-05-08
公開日2013-06-26
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Conserved regulatory elements in AMPK
Nature, 498, 2013
1NB8
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Structure of the catalytic domain of USP7 (HAUSP)
分子名称: Ubiquitin carboxyl-terminal hydrolase 7
著者Hu, M, Li, P, Li, M, Li, W, Yao, T, Wu, J.-W, Gu, W, Cohen, R.E, Shi, Y.
登録日2002-12-02
公開日2003-01-07
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde
Cell(Cambridge,Mass.), 111, 2002
1LCY
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BU of 1lcy by Molmil
Crystal Structure of the Mitochondrial Serine Protease HtrA2
分子名称: HtrA2 serine protease
著者Li, W, Srinivasula, S.M, Chai, J, Li, P, Wu, J.W, Zhang, Z, Alnemri, E.S, Shi, Y.
登録日2002-04-07
公開日2002-05-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi.
Nat.Struct.Biol., 9, 2002
1SJ0
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BU of 1sj0 by Molmil
Human Estrogen Receptor Alpha Ligand-binding Domain in Complex with the Antagonist Ligand 4-D
分子名称: (2S,3R)-2-(4-(2-(PIPERIDIN-1-YL)ETHOXY)PHENYL)-2,3-DIHYDRO-3-(4-HYDROXYPHENYL)BENZO[B][1,4]OXATHIIN-6-OL, Estrogen receptor
著者Kim, S, Wu, J.Y, Birzin, E.T, Chan, W, Pai, L.Y, Yang, Y.T, Mosley, R.T, Fitzgerald, P.M, Sharma, N, DiNinno, F, Rohrer, S.P, Schaeffer, J.M, Hammond, M.L.
登録日2004-03-02
公開日2004-04-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Estrogen Receptor Ligands. II. Discovery of Benzoxathiins as Potent, Selective Estrogen Receptor alpha Modulators.
J.Med.Chem., 47, 2004
1RZM
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BU of 1rzm by Molmil
Crystal structure of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHPS) from Thermotoga maritima complexed with Cd2+, PEP and E4P
分子名称: CADMIUM ION, ERYTHOSE-4-PHOSPHATE, PHOSPHOENOLPYRUVATE, ...
著者Shumilin, I.A, Bauerle, R, Wu, J, Woodard, R.W, Kretsinger, R.H.
登録日2003-12-24
公開日2004-08-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the Reaction Complex of 3-Deoxy-d-arabino-heptulosonate-7-phosphate Synthase from Thermotoga maritima Refines the Catalytic Mechanism and Indicates a New Mechanism of Allosteric Regulation.
J.Mol.Biol., 341, 2004
3IDB
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BU of 3idb by Molmil
Crystal structure of (108-268)RIIb:C holoenzyme of cAMP-dependent protein kinase
分子名称: MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, cAMP-dependent protein kinase catalytic subunit alpha, ...
著者Brown, S.H.J, Wu, J, Kim, C, Alberto, K, Taylor, S.S.
登録日2009-07-20
公開日2009-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Novel isoform-specific interfaces revealed by PKA RIIbeta holoenzyme structures.
J.Mol.Biol., 393, 2009
2XW9
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Crystal Structure of Complement Factor D mutant S183A
分子名称: COMPLEMENT FACTOR D, GLYCEROL
著者Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P.
登録日2010-11-01
公開日2011-01-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
3IDC
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Crystal structure of (102-265)RIIb:C holoenzyme of cAMP-dependent protein kinase
分子名称: MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, cAMP-dependent protein kinase catalytic subunit alpha, ...
著者Brown, S.H.J, Wu, J, Kim, C, Alberto, K, Taylor, S.S.
登録日2009-07-20
公開日2009-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Novel isoform-specific interfaces revealed by PKA RIIbeta holoenzyme structures.
J.Mol.Biol., 393, 2009
6VGU
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BU of 6vgu by Molmil
Crystal structure of FERM-folded talin head domain bound to the NPLY motif of beta3-integrin
分子名称: Integrin beta-3,Talin-1
著者Zhang, P, Sun, Y, Wu, J.
登録日2020-01-09
公開日2020-12-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Crystal structure of the FERM-folded talin head reveals the determinants for integrin binding.
Proc.Natl.Acad.Sci.USA, 117, 2020
2XWA
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Crystal Structure of Complement Factor D Mutant R202A
分子名称: COMPLEMENT FACTOR D, GLYCEROL
著者Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P.
登録日2010-11-01
公開日2011-01-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
1M59
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Crystal Structure of P40V Mutant of Trypsin-solubilized Fragment of Cytochrome b5
分子名称: Cytochrome b5, PROTOPORPHYRIN IX CONTAINING FE
著者Wang, Z.-Q, Wu, J, Wang, Y.-H, Qian, W, Xie, Y, Xia, Z.-X, Huang, Z.-X.
登録日2002-07-09
公開日2003-03-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Proline40 is essential to maintaining cytochrome b5 stability and its electron transfer with cytochrome c
Chin.J.Chem., 20, 2002

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