4FE2
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![BU of 4fe2 by Molmil](/molmil-images/mine/4fe2) | X-Ray Structure of SAICAR Synthetase (PurC) from Streptococcus pneumoniae complexed with AIR, ADP, Asp and Mg2+ | Descriptor: | 5-AMINOIMIDAZOLE RIBONUCLEOTIDE, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Wolf, N, Abad-Zapatero, C, Johnson, M.E, Fung, L.M.-W. | Deposit date: | 2012-05-29 | Release date: | 2013-05-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.288 Å) | Cite: | Structures of SAICAR synthetase (PurC) from Streptococcus pneumoniae with ADP, Mg(2+), AIR and Asp. Acta Crystallogr.,Sect.D, 70, 2014
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1JEI
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![BU of 1jei by Molmil](/molmil-images/mine/1jei) | LEM DOMAIN OF HUMAN INNER NUCLEAR MEMBRANE PROTEIN EMERIN | Descriptor: | EMERIN | Authors: | Wolff, N, Gilquin, B, Courchay, K, Callebaut, I, Zinn-Justin, S. | Deposit date: | 2001-06-18 | Release date: | 2001-07-04 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural analysis of emerin, an inner nuclear membrane protein mutated in X-linked Emery-Dreifuss muscular dystrophy FEBS LETT., 501, 2001
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1YBJ
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![BU of 1ybj by Molmil](/molmil-images/mine/1ybj) | Structural and Dynamics studies of both apo and holo forms of the hemophore HasA | Descriptor: | Hemophore HasA | Authors: | Wolff, N, Izadi-Pruneyre, N, Couprie, J, Habeck, M, Linge, J, Rieping, W, Wandersman, C, Nilges, M, Delepierre, M, Lecroisey, A. | Deposit date: | 2004-12-21 | Release date: | 2005-12-27 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Comparative analysis of structural and dynamic properties of the loaded and unloaded hemophore HasA: functional implications. J.Mol.Biol., 376, 2008
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4FGR
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![BU of 4fgr by Molmil](/molmil-images/mine/4fgr) | X-Ray Structure of SAICAR Synthetase (PurC) from Streptococcus pneumoniae complexed with ADP and Mg2+ | Descriptor: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | Authors: | Fung, L.W.-M, Johnson, M.E, Abad-Zapatero, C, Wolf, N.W. | Deposit date: | 2012-06-04 | Release date: | 2013-06-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.597 Å) | Cite: |
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6UCR
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![BU of 6ucr by Molmil](/molmil-images/mine/6ucr) | Structure of ClpC1-NTD L92S L96P | Descriptor: | ACETATE ION, Negative regulator of genetic competence ClpC/mecB | Authors: | Abad-Zapatero, C, Wolf, N.M. | Deposit date: | 2019-09-17 | Release date: | 2020-05-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the N-terminal domain of ClpC1 in complex with the antituberculosis natural product ecumicin reveals unique binding interactions. Acta Crystallogr D Struct Biol, 76, 2020
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6CN8
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![BU of 6cn8 by Molmil](/molmil-images/mine/6cn8) | High-resolution structure of ClpC1-NTD binding to Rufomycin-I | Descriptor: | ATP-dependent Clp protease ATP-binding subunit ClpC1, CHLORIDE ION, PHOSPHATE ION, ... | Authors: | Abad-Zapatero, C, Wolf, N.W. | Deposit date: | 2018-03-07 | Release date: | 2019-06-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | High-Resolution Structure of ClpC1-Rufomycin and Ligand Binding Studies Provide a Framework to Design and Optimize Anti-Tuberculosis Leads. Acs Infect Dis., 5, 2019
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6AYV
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![BU of 6ayv by Molmil](/molmil-images/mine/6ayv) | Crystal structure of fructose-1,6-bisphosphatase T84A from Mycobacterium tuberculosis | Descriptor: | 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase class 2, GLYCEROL, ... | Authors: | Abad-Zapatero, C, Wolf, N, Gutka, H.J, Movahedzadeh, F. | Deposit date: | 2017-09-08 | Release date: | 2018-03-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of the Mycobacterium tuberculosis GlpX protein (class II fructose-1,6-bisphosphatase): implications for the active oligomeric state, catalytic mechanism and citrate inhibition. Acta Crystallogr D Struct Biol, 74, 2018
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6PBS
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![BU of 6pbs by Molmil](/molmil-images/mine/6pbs) | Structure of ClpC1-NTD in complex with Ecumicin | Descriptor: | ACETATE ION, ATP-dependent Clp protease ATP-binding subunit ClpC1, ecumicin | Authors: | Abad-Zapatero, C, Wolf, N.M. | Deposit date: | 2019-06-14 | Release date: | 2020-05-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the N-terminal domain of ClpC1 in complex with the antituberculosis natural product ecumicin reveals unique binding interactions. Acta Crystallogr D Struct Biol, 76, 2020
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6AYU
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![BU of 6ayu by Molmil](/molmil-images/mine/6ayu) | Crystal structure of fructose-1,6-bisphosphatase T84S from Mycobacterium tuberculosis | Descriptor: | 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase class 2, GLYCEROL, ... | Authors: | Abad-Zapatero, C, Wolf, N, Gutka, H.J, Movahedzadeh, F. | Deposit date: | 2017-09-08 | Release date: | 2018-03-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structures of the Mycobacterium tuberculosis GlpX protein (class II fructose-1,6-bisphosphatase): implications for the active oligomeric state, catalytic mechanism and citrate inhibition. Acta Crystallogr D Struct Biol, 74, 2018
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6AYY
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![BU of 6ayy by Molmil](/molmil-images/mine/6ayy) | Crystal structure of Apo fructose-1,6-bisphosphatase from Mycobacterium tuberculosis | Descriptor: | CITRIC ACID, Fructose-1,6-bisphosphatase class 2, GLYCEROL, ... | Authors: | Abad-Zapatero, C, Wolf, N, Gutka, H.J, Movahedzadeh, F. | Deposit date: | 2017-09-08 | Release date: | 2018-03-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Structures of the Mycobacterium tuberculosis GlpX protein (class II fructose-1,6-bisphosphatase): implications for the active oligomeric state, catalytic mechanism and citrate inhibition. Acta Crystallogr D Struct Biol, 74, 2018
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6PBA
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![BU of 6pba by Molmil](/molmil-images/mine/6pba) | Structure of ClpC1-NTD | Descriptor: | ATP-dependent Clp protease ATP-binding subunit ClpC1 | Authors: | Abad-Zapatero, C, Wolf, N.M. | Deposit date: | 2019-06-13 | Release date: | 2020-05-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structure of the N-terminal domain of ClpC1 in complex with the antituberculosis natural product ecumicin reveals unique binding interactions. Acta Crystallogr D Struct Biol, 76, 2020
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6PBQ
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![BU of 6pbq by Molmil](/molmil-images/mine/6pbq) | Structure of ClpC1-NTD | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ATP-dependent Clp protease ATP-binding subunit ClpC1, PHOSPHATE ION | Authors: | Abad-Zapatero, C, Wolf, N.M. | Deposit date: | 2019-06-14 | Release date: | 2020-05-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of the N-terminal domain of ClpC1 in complex with the antituberculosis natural product ecumicin reveals unique binding interactions. Acta Crystallogr D Struct Biol, 76, 2020
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7JS3
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![BU of 7js3 by Molmil](/molmil-images/mine/7js3) | Structure of the Class II Fructose-1,6-Bisphophatase from Francisella tularensis | Descriptor: | Fructose-1,6-bisphosphatase, GLYCEROL, MAGNESIUM ION | Authors: | Abad-Zapatero, C, Wolf, N.M, Movahedzadeh, F, Gutka, H, Selezneva, A. | Deposit date: | 2020-08-13 | Release date: | 2020-11-04 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural and biochemical characterization of the class II fructose-1,6-bisphosphatase from Francisella tularensis. Acta Crystallogr.,Sect.F, 76, 2020
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4NYE
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![BU of 4nye by Molmil](/molmil-images/mine/4nye) | Structures of SAICAR Synthetase (PurC) from Streptococcus pneumoniae with ADP, Mg2+, AIR and L-Asp | Descriptor: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | Authors: | Fung, L.W.-M, Johnson, M.E, Abad-Zapatero, C, Wolf, N.M. | Deposit date: | 2013-12-10 | Release date: | 2014-04-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Structures of SAICAR synthetase (PurC) from Streptococcus pneumoniae with ADP, Mg(2+), AIR and Asp. Acta Crystallogr.,Sect.D, 70, 2014
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5EYZ
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![BU of 5eyz by Molmil](/molmil-images/mine/5eyz) | CRYSTAL STRUCTURE OF THE PTPN4 PDZ DOMAIN COMPLEXED WITH THE TAILORED PEPTIDE CYTO8-RETEV | Descriptor: | CHLORIDE ION, CYTO8-RETEV, Tyrosine-protein phosphatase non-receptor type 4 | Authors: | Maisonneuve, P, Vaney, M.C, Babault, B, Caillet-Saguy, C, Lafon, M, Delepierre, M, Cordier, F, Wolff, N. | Deposit date: | 2015-11-26 | Release date: | 2016-06-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38 gamma. J.Biol.Chem., 291, 2016
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5EZ0
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![BU of 5ez0 by Molmil](/molmil-images/mine/5ez0) | CRYSTAL STRUCTURE OF THE PTPN4 PDZ DOMAIN COMPLEXED WITH THE PDZ BINDING MOTIF OF THE MITOGEN ACTIVATED PROTEIN KINASE P38GAMMA. | Descriptor: | Mitogen-activated protein kinase 12, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 4 | Authors: | Maisonneuve, P, Vaney, M.C, Caillet-Saguy, C, Lafon, M, Delepierre, M, Cordier, F, Wolff, N. | Deposit date: | 2015-11-26 | Release date: | 2016-06-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38 gamma. J.Biol.Chem., 291, 2016
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6Y38
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![BU of 6y38 by Molmil](/molmil-images/mine/6y38) | Crystal structure of Whirlin PDZ3 in complex with Myosin 15a C-terminal PDZ binding motif peptide | Descriptor: | Chains: C,D, Whirlin | Authors: | Zhu, Y, Delhommel, F, Haouz, A, Caillet-Saguy, C, Vaney, M, Mechaly, A.E, Wolff, N. | Deposit date: | 2020-02-17 | Release date: | 2020-10-07 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.697 Å) | Cite: | Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners. J.Mol.Biol., 432, 2020
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6Y9P
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![BU of 6y9p by Molmil](/molmil-images/mine/6y9p) | Crystal structure of Whirlin PDZ3_C-ter in complex with Harmonin a1 C-terminal PDZ binding motif peptide | Descriptor: | Harmonin a1, Whirlin | Authors: | Zhu, Y, Delhommel, F, Haouz, A, Caillet-Saguy, C, Vaney, M, Mechaly, A.E, Wolff, N. | Deposit date: | 2020-03-10 | Release date: | 2020-10-07 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.169 Å) | Cite: | Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners. J.Mol.Biol., 432, 2020
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6Y9N
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![BU of 6y9n by Molmil](/molmil-images/mine/6y9n) | Crystal structure of Whirlin PDZ3_C-ter in complex with Myosin 15a C-terminal PDZ binding motif peptide | Descriptor: | Unconventional myosin-XV, Whirlin | Authors: | Zhu, Y, Delhommel, F, Haouz, A, Caillet-Saguy, C, Vaney, M, Mechaly, A.E, Wolff, N. | Deposit date: | 2020-03-10 | Release date: | 2020-10-07 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners. J.Mol.Biol., 432, 2020
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6Y9O
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![BU of 6y9o by Molmil](/molmil-images/mine/6y9o) | Crystal structure of Whirlin PDZ3_C-ter in complex with CASK internal PDZ binding motif peptide | Descriptor: | Peripheral plasma membrane protein CASK, Whirlin | Authors: | Zhu, Y, Delhommel, F, Haouz, A, Caillet-Saguy, C, Vaney, M, Mechaly, A.E, Wolff, N. | Deposit date: | 2020-03-10 | Release date: | 2020-10-07 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.632 Å) | Cite: | Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners. J.Mol.Biol., 432, 2020
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6Y9Q
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![BU of 6y9q by Molmil](/molmil-images/mine/6y9q) | Crystal structure of Whirlin PDZ3_C-ter in complex with Taperin internal PDZ binding motif peptide | Descriptor: | Taperin, Whirlin | Authors: | Zhu, Y, Delhommel, F, Haouz, A, Caillet-Saguy, C, Vaney, M, Mechaly, A.E, Wolff, N. | Deposit date: | 2020-03-10 | Release date: | 2020-10-07 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.315 Å) | Cite: | Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners. J.Mol.Biol., 432, 2020
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8CQY
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![BU of 8cqy by Molmil](/molmil-images/mine/8cqy) | Crystal structure of the PTPN3 PDZ domain bound to the PBM TACE C-terminal peptide | Descriptor: | Disintegrin and metalloproteinase domain-containing protein 17, SODIUM ION, Tyrosine-protein phosphatase non-receptor type 3 | Authors: | Genera, M, Colcombet-Cazenave, B, Croitoru, A, Raynal, B, Mechaly, A, Caillet, J, Haouz, A, Wolff, N, Caillet-Saguy, C. | Deposit date: | 2023-03-07 | Release date: | 2023-05-10 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity. Front Mol Biosci, 10, 2023
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6FDE
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![BU of 6fde by Molmil](/molmil-images/mine/6fde) | Crystal Structure of the HHD2 Domain of Whirlin : 3-helix conformation | Descriptor: | Whirlin | Authors: | Delhommel, F, Cordier, F, Saul, F, Haouz, A, Wolff, N. | Deposit date: | 2017-12-22 | Release date: | 2018-08-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural plasticity of the HHD2 domain of whirlin. FEBS J., 285, 2018
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6FDD
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![BU of 6fdd by Molmil](/molmil-images/mine/6fdd) | Crystal Structure of the HHD2 Domain of Whirlin | Descriptor: | SULFATE ION, Whirlin | Authors: | Delhommel, F, Cordier, F, Saul, F, Haouz, A, Wolff, N. | Deposit date: | 2017-12-22 | Release date: | 2018-08-08 | Last modified: | 2018-10-31 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural plasticity of the HHD2 domain of whirlin. FEBS J., 285, 2018
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8OEP
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![BU of 8oep by Molmil](/molmil-images/mine/8oep) | Crystal structure of the PTPN3 PDZ domain bound to the HPV18 E6 oncoprotein C-terminal peptide | Descriptor: | Protein E6, SODIUM ION, Tyrosine-protein phosphatase non-receptor type 3 | Authors: | Genera, M, Colcombet-Cazenave, B, Croitoru, A, Raynal, B, Mechaly, A, Caillet, J, Haouz, A, Wolff, N, Caillet-Saguy, C. | Deposit date: | 2023-03-11 | Release date: | 2023-05-10 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity. Front Mol Biosci, 10, 2023
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