6PBS

Structure of ClpC1-NTD in complex with Ecumicin

Summary for 6PBS

• Entry DOI: 10.2210/pdb6pbs/pdb
• Related PRD ID: PRD_002456
• Descriptor: ATP-dependent Clp protease ATP-binding subunit ClpC1, ecumicin, ACETATE ION, ... (4 entities in total)
• Functional Keywords: clpc1-ntd, ecumicin, atpase, mycobacterium tuberculosis, chaperone-antibiotic complex, chaperone/antibiotic
• Biological source: Mycobacterium tuberculosis; More
• Total number of polymer chains: 36
• Total formula weight: 250363.68

Authors

Abad-Zapatero, C.,Wolf, N.M. (deposition date: 2019-06-14, release date: 2020-05-13, Last modification date: 2023-11-15)

• Primary citation: Wolf, N.M.,Lee, H.,Zagal, D.,Nam, J.W.,Oh, D.C.,Lee, H.,Suh, J.W.,Pauli, G.F.,Cho, S.,Abad-Zapatero, C.; Structure of the N-terminal domain of ClpC1 in complex with the antituberculosis natural product ecumicin reveals unique binding interactions.; Acta Crystallogr D Struct Biol, 76:458-471, 2020; PubMed: 32355042; DOI: 10.1107/S2059798320004027

Experimental method

X-RAY DIFFRACTION (2.5 Å)