1YRN
 
 | | CRYSTAL STRUCTURE OF THE MATA1/MATALPHA2 HOMEODOMAIN HETERODIMER BOUND TO DNA | | 分子名称: | DNA (5'-D(*TP*AP*CP*AP*TP*GP*TP*AP*AP*TP*TP*TP*AP*TP*TP*AP*C P*AP*TP*CP*A)-3'), DNA (5'-D(*TP*AP*TP*GP*AP*TP*GP*TP*AP*AP*TP*AP*AP*AP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MAT A1 HOMEODOMAIN), ... | | 著者 | Li, T, Stark, M.R, Johnson, A.D, Wolberger, C. | | 登録日 | 1995-11-02 | | 公開日 | 1996-01-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of the MATa1/MAT alpha 2 homeodomain heterodimer bound to DNA.
Science, 270, 1995
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8T3W
 | | Structure of Bre1-nucleosome complex - state2 | | 分子名称: | 601 DNA strand 1, 601 DNA strand 2, E3 ubiquitin-protein ligase BRE1, ... | | 著者 | Zhao, F, Hicks, C.W, Wolberger, C. | | 登録日 | 2023-06-07 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Mechanism of histone H2B monoubiquitination by Bre1.
Nat.Struct.Mol.Biol., 30, 2023
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8T3T
 | | Structure of Bre1-nucleosome complex - state3 | | 分子名称: | 601 DNA strand 1, 601 DNA strand 2, E3 ubiquitin-protein ligase BRE1, ... | | 著者 | Zhao, F, Hicks, C.W, Wolberger, C. | | 登録日 | 2023-06-07 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Mechanism of histone H2B monoubiquitination by Bre1.
Nat.Struct.Mol.Biol., 30, 2023
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8T3Y
 | | Structure of Bre1-nucleosome complex - state1 | | 分子名称: | 601 DNA Strand 1, 601 DNA Strand 2, E3 ubiquitin-protein ligase BRE1, ... | | 著者 | Zhao, F, Hicks, C.W, Wolberger, C. | | 登録日 | 2023-06-08 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Mechanism of histone H2B monoubiquitination by Bre1.
Nat.Struct.Mol.Biol., 30, 2023
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3MHH
 | | Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module | | 分子名称: | Protein SUS1, SAGA-associated factor 11, SAGA-associated factor 73, ... | | 著者 | Samara, N.L, Datta, A.B, Berndsen, C.E, Zhang, X, Yao, T, Cohen, R.E, Wolberger, C. | | 登録日 | 2010-04-08 | | 公開日 | 2010-04-21 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structural insights into the assembly and function of the SAGA deubiquitinating module.
Science, 328, 2010
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3MHS
 | | Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module bound to ubiquitin aldehyde | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Protein SUS1, ... | | 著者 | Samara, N.L, Datta, A.B, Berndsen, C.E, Zhang, X, Yao, T, Cohen, R.E, Wolberger, C. | | 登録日 | 2010-04-08 | | 公開日 | 2010-04-21 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Structural insights into the assembly and function of the SAGA deubiquitinating module.
Science, 328, 2010
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2CRO
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2ARC
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3HM3
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3JR3
 | | Sir2 bound to acetylated peptide | | 分子名称: | Acetylated Peptide, NAD-dependent deacetylase, ZINC ION | | 著者 | Hawse, W.F, Wolberger, C. | | 登録日 | 2009-09-08 | | 公開日 | 2009-09-29 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure-based mechanism of ADP-ribosylation by sirtuins.
J.Biol.Chem., 284, 2009
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4R62
 | | Structure of Rad6~Ub | | 分子名称: | ACETATE ION, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 2 | | 著者 | Kumar, P, Wolberger, C. | | 登録日 | 2014-08-22 | | 公開日 | 2015-09-02 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Role of a non-canonical surface of Rad6 in ubiquitin conjugating activity.
Nucleic Acids Res., 43, 2015
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4R7E
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8V25
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8V28
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8V26
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8V27
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6NOG
 | | Poised-state Dot1L bound to the H2B-Ubiquitinated nucleosome | | 分子名称: | 601 DNA Strand 1, 601 DNA Strand 2, Histone H2A type 1, ... | | 著者 | Worden, E.J, Hoffmann, N.A, Wolberger, C. | | 登録日 | 2019-01-16 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
Cell, 176, 2019
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6NJ9
 | | Active state Dot1L bound to the H2B-Ubiquitinated nucleosome, 2-to-1 complex | | 分子名称: | 601 DNA Strand 1, 601 DNA Strand 2, Histone H2A type 1, ... | | 著者 | Worden, E.J, Hoffmann, N.A, Wolberger, C. | | 登録日 | 2019-01-02 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | | 主引用文献 | Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
Cell, 176, 2019
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6NQA
 | | Active state Dot1L bound to the H2B-Ubiquitinated nucleosome, 1-to-1 complex | | 分子名称: | 601 DNA Strand 1, 601 DNA Strand 2, Histone H2A type 1, ... | | 著者 | Worden, E.J, Hoffmann, N.A, Wolberger, C. | | 登録日 | 2019-01-19 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
Cell, 176, 2019
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4DHI
 | | Structure of C. elegans OTUB1 bound to human UBC13 | | 分子名称: | Ubiquitin thioesterase otubain-like, Ubiquitin-conjugating enzyme E2 N | | 著者 | Wiener, R, Zhang, X, Wang, T, Wolberger, C. | | 登録日 | 2012-01-27 | | 公開日 | 2012-02-22 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The mechanism of OTUB1-mediated inhibition of ubiquitination.
Nature, 483, 2012
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1YC2
 | | Sir2Af2-NAD-ADPribose-nicotinamide | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5-DIPHOSPHORIBOSE, NAD-dependent deacetylase 2, ... | | 著者 | Avalos, J.L, Bever, M.K, Wolberger, C. | | 登録日 | 2004-12-21 | | 公開日 | 2005-03-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Mechanism of Sirtuin Inhibition by Nicotinamide: Altering the NAD(+) Cosubstrate Specificity of a Sir2 Enzyme.
Mol.Cell, 17, 2005
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1YC5
 | | Sir2-p53 peptide-nicotinamide | | 分子名称: | Cellular tumor antigen p53 peptide, NAD-dependent deacetylase, NICOTINAMIDE, ... | | 著者 | Avalos, J.L, Bever, M.K, Wolberger, C. | | 登録日 | 2004-12-21 | | 公開日 | 2005-04-26 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme.
Mol.Cell, 17, 2005
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4DHJ
 | | The structure of a ceOTUB1 ubiquitin aldehyde UBC13~Ub complex | | 分子名称: | Ubiquitin, Ubiquitin aldehyde, Ubiquitin thioesterase otubain-like, ... | | 著者 | Wiener, R, Zhang, X, Wang, T, Wolberger, C. | | 登録日 | 2012-01-27 | | 公開日 | 2012-02-22 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | The mechanism of OTUB1-mediated inhibition of ubiquitination.
Nature, 483, 2012
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4DHZ
 | | The structure of h/ceOTUB1-ubiquitin aldehyde-UBC13~Ub | | 分子名称: | Ubiquitin, Ubiquitin aldehyde, Ubiquitin thioesterase otubain-like, ... | | 著者 | Wiener, R, Zhang, X, Wang, T, Wolberger, C. | | 登録日 | 2012-01-30 | | 公開日 | 2012-02-22 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | | 主引用文献 | The mechanism of OTUB1-mediated inhibition of ubiquitination.
Nature, 483, 2012
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3D4B
 | | Crystal structure of Sir2Tm in complex with Acetyl p53 peptide and DADMe-NAD+ | | 分子名称: | 5'-O-[(R)-{[(R)-{[(3R,4R)-1-(3-carbamoylbenzyl)-4-hydroxypyrrolidin-3-yl]methoxy}(hydroxy)phosphoryl]methyl}(hydroxy)phosphoryl]adenosine, Acetyl P53 peptide, NAD-dependent deacetylase, ... | | 著者 | Hawse, W.F, Hoff, K.G, Fatkins, D, Daines, A, Zubkova, O.V, Schramm, V.L, Zheng, W, Wolberger, C. | | 登録日 | 2008-05-14 | | 公開日 | 2008-09-30 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural insights into intermediate steps in the Sir2 deacetylation reaction.
Structure, 16, 2008
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