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PDB: 871 件
7LKA
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Crystal structure of SARS-CoV-2 RBD-targeting antibody COV107-23
分子名称: ACETATE ION, COV107-23 heavy chain, COV107-23 light chain
著者Yuan, M, Zhu, X, Wilson, I.A, Wu, N.C.
登録日2021-02-02
公開日2021-02-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.981 Å)
主引用文献Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain.
Nat Commun, 12, 2021
7LK9
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Crystal structure of SARS-CoV-2 RBD-targeting antibody COV107-23 HC + COVD21-C8 LC
分子名称: COV107-23 heavy chain, COVD21-C8 light chain
著者Yuan, M, Zhu, X, Wilson, I.A, Wu, N.C.
登録日2021-02-01
公開日2021-02-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain.
Nat Commun, 12, 2021
7LM8
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Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with two cross-neutralizing antibodies CV38-142 and COVA1-16 Fabs isolated from COVID-19 patients
分子名称: 1,2-ETHANEDIOL, COVA1-16 Fab heavy chain, COVA1-16 Fab light chain, ...
著者Liu, H, Wilson, I.A.
登録日2021-02-05
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.936 Å)
主引用文献A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection.
Cell Host Microbe, 29, 2021
7LM9
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Crystal structure of SARS-CoV spike protein receptor-binding domain in complex with a cross-neutralizing antibody CV38-142 Fab isolated from COVID-19 patient
分子名称: 1,2-ETHANEDIOL, CV38-142 Fab heavy chain, CV38-142 Fab light chain, ...
著者Liu, H, Yuan, M, Zhu, X, Wilson, I.A.
登録日2021-02-05
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection.
Cell Host Microbe, 29, 2021
1GGB
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BU of 1ggb by Molmil
MAJOR ANTIGEN-INDUCED DOMAIN REARRANGEMENTS IN AN ANTIBODY
分子名称: IGG2A-KAPPA 50.1 FAB (HEAVY CHAIN), IGG2A-KAPPA 50.1 FAB (LIGHT CHAIN)
著者Takimoto-Kamimura, M, Wilson, I.A.
登録日1993-07-19
公開日1993-10-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Major antigen-induced domain rearrangements in an antibody.
Structure, 1, 1993
1GGC
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BU of 1ggc by Molmil
MAJOR ANTIGEN-INDUCED DOMAIN REARRANGEMENTS IN AN ANTIBODY
分子名称: IGG2A-KAPPA 50.1 FAB (HEAVY CHAIN), IGG2A-KAPPA 50.1 FAB (LIGHT CHAIN)
著者Takimoto-Kamimura, M, Wilson, I.A.
登録日1993-07-19
公開日1993-10-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Major antigen-induced domain rearrangements in an antibody.
Structure, 1, 1993
1GGI
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BU of 1ggi by Molmil
CRYSTAL STRUCTURE OF AN HIV-1 NEUTRALIZING ANTIBODY 50.1 IN COMPLEX WITH ITS V3 LOOP PEPTIDE ANTIGEN
分子名称: HIV-1 V3 LOOP PEPTIDE ANTIGEN, IGG2A 50.1 FAB (HEAVY CHAIN), IGG2A 50.1 FAB (LIGHT CHAIN)
著者Stanfield, R.L, Rini, J.M, Wilson, I.A.
登録日1993-04-02
公開日1993-10-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of a human immunodeficiency virus type 1 neutralizing antibody, 50.1, in complex with its V3 loop peptide antigen.
Proc.Natl.Acad.Sci.USA, 90, 1993
5E30
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BU of 5e30 by Molmil
Crystal structure of H5 hemagglutinin Q226L mutant from the influenza virus A/duck/Egypt/10185SS/2010 (H5N1) with LSTc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, ...
著者Zhu, X, Wilson, I.A.
登録日2015-10-01
公開日2015-12-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants.
Cell Rep, 13, 2015
5E35
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Crystal structure of H5 hemagglutinin mutant (N224K, Q226L, N158D and L133a deletion) from the influenza virus A/chicken/Vietnam/NCVD-093/2008 (H5N1) with LSTc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Zhu, X, Wilson, I.A.
登録日2015-10-01
公開日2015-12-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants.
Cell Rep, 13, 2015
5E2Z
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Crystal structure of H5 hemagglutinin Q226L mutant from the influenza virus A/duck/Egypt/10185SS/2010 (H5N1) with LSTa
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, ...
著者Zhu, X, Wilson, I.A.
登録日2015-10-01
公開日2015-12-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.624 Å)
主引用文献Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants.
Cell Rep, 13, 2015
5E34
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BU of 5e34 by Molmil
Crystal structure of H5 hemagglutinin mutant (N224K, Q226L, N158D and L133a deletion) from the influenza virus A/chicken/Vietnam/NCVD-093/2008 (H5N1) with LSTa
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Zhu, X, Wilson, I.A.
登録日2015-10-01
公開日2015-12-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants.
Cell Rep, 13, 2015
5E2Y
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BU of 5e2y by Molmil
Crystal structure of H5 hemagglutinin Q226L mutant from the influenza virus A/duck/Egypt/10185SS/2010 (H5N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, beta-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhu, X, Wilson, I.A.
登録日2015-10-01
公開日2015-12-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants.
Cell Rep, 13, 2015
5E32
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BU of 5e32 by Molmil
Crystal structure of H5 hemagglutinin mutant (N224K, Q226L, N158D and L133a deletion) from the influenza virus A/chicken/Vietnam/NCVD-093/2008 (H5N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin
著者Zhu, X, Wilson, I.A.
登録日2015-10-01
公開日2015-12-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants.
Cell Rep, 13, 2015
5E99
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BU of 5e99 by Molmil
Bovine Fab fragment F08_B11
分子名称: Fab F08_B11 heavy chain, Fab F08_B11 light chain
著者Stanfield, R.L, Wilson, I.A.
登録日2015-10-14
公開日2016-08-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies.
Sci Immunol, 1, 2016
1VAD
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BU of 1vad by Molmil
MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND YEAST ALPHA-GLUCOSIDASE
分子名称: BETA-2 MICROGLOBULIN, MHC CLASS I H-2KB HEAVY CHAIN, YEAST ALPHA-GLUCOSIDASE
著者Fremont, D.H, Wilson, I.A.
登録日1994-11-01
公開日1996-06-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of an H-2Kb-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove.
Proc.Natl.Acad.Sci.USA, 92, 1995
5FEH
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BU of 5feh by Molmil
Crystal structure of PCT64_35B, a broadly neutralizing anti-HIV antibody
分子名称: 1,2-ETHANEDIOL, PCT64_26 Fab heavy chain, PCT64_26 Fab light chain, ...
著者Murrell, S, Wilson, I.A.
登録日2015-12-17
公開日2017-08-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage.
Immunity, 47, 2017
5HZQ
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BU of 5hzq by Molmil
Crystal structure of cellular retinoic acid binding protein 2 (CRABP2)-aryl fluorosulfate covalent conjugate
分子名称: 4'-[(3,6,9,12-tetraoxapentadec-14-yn-1-yl)oxy][1,1'-biphenyl]-4-yl sulfurofluoridate, Cellular retinoic acid-binding protein 2, GLYCEROL
著者Chen, W, Mortenson, D.E, Wilson, I.A, Kelly, J.W.
登録日2016-02-02
公開日2016-06-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue.
J.Am.Chem.Soc., 138, 2016
5ILT
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BU of 5ilt by Molmil
Crystal structure of bovine Fab A01
分子名称: bovine Fab A01 heavy chain, bovine Fab A01 light chain
著者Stanfield, R.L, Wilson, I.A.
登録日2016-03-04
公開日2016-08-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies.
Sci Immunol, 1, 2016
5IF0
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Crystal structure of VRC01c-HuGL2 Fab from an HIV-1 naive donor in complex with with a germline-targeting gp120 engineered outer domain eOD-GT8 at 2.44 A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Germline-targeting HIV-1 gp120 engineered outer domain eOD-GT8, PHOSPHATE ION, ...
著者Sarkar, A, Wilson, I.A.
登録日2016-02-25
公開日2016-04-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen.
Science, 351, 2016
5IJV
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BU of 5ijv by Molmil
Crystal structure of bovine Fab E03
分子名称: bovine Fab E03 heavy chain, bovine Fab E03 light chain
著者Stanfield, R.L, Wilson, I.A.
登録日2016-03-02
公開日2016-10-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies.
Sci Immunol, 1, 2016
5IDL
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BU of 5idl by Molmil
Crystal structure of the germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT8
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT8
著者Julien, J.P, Ereno-Orbea, J, Jardine, J.G, Schief, W.R, Wilson, I.A.
登録日2016-02-24
公開日2016-10-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen.
Science, 351, 2016
5IES
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BU of 5ies by Molmil
Crystal structure of VRC01c-HuGL2 Fab from an HIV-1 naive donor in complex with with a germline-targeting gp120 engineered outer domain eOD-GT8 at 2.16 A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Germline-targeting HIV-1 gp120 engineered outer domain eOD-GT8, ...
著者Sarkar, A, Wilson, I.A.
登録日2016-02-25
公開日2016-04-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen.
Science, 351, 2016
6OO0
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BU of 6oo0 by Molmil
Crystal structure of bovine Fab NC-Cow1
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, NC-Cow1 heavy chain, NC-Cow1 light chain
著者Stanfield, R.L, Wilson, I.A.
登録日2019-04-22
公開日2020-04-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of broad HIV neutralization by a vaccine-induced cow antibody.
Sci Adv, 6, 2020
6O3U
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Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3 in complex with 06:0 PA
分子名称: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, GLYCEROL, PGZL1.H4K3 heavy chain, ...
著者Irimia, A, Wilson, I.A.
登録日2019-02-27
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.105 Å)
主引用文献An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nat Commun, 10, 2019
6OPA
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BU of 6opa by Molmil
Crystal structure of bovine Fab NC-Cow1 in complex with HIV-1 BG505 SOSIP.664, and human Fabs 35022 and PGT128
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
著者Stanfield, R.L, Wilson, I.A.
登録日2019-04-24
公開日2020-04-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.084 Å)
主引用文献Structural basis of broad HIV neutralization by a vaccine-induced cow antibody.
Sci Adv, 6, 2020

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