3KPQ
 
 | | Crystal Structure of HLA B*4405 in complex with EEYLKAWTF, a mimotope | | 分子名称: | Beta-2-microglobulin, EEYLKAWTF, mimotope peptide, ... | | 著者 | Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J. | | 登録日 | 2009-11-16 | | 公開日 | 2009-12-22 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
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2AK4
 | | Crystal Structure of SB27 TCR in complex with HLA-B*3508-13mer peptide | | 分子名称: | Beta-2-microglobulin, EBV peptide LPEPLPQGQLTAY, HLA-B35 variant, ... | | 著者 | Tynan, F.E, Burrows, S.R, Buckle, A.M, Clements, C.S, Borg, N.A, Miles, J.J, Beddoe, T, Whisstock, J.C, Wilce, M.C, Silins, S.L, Burrows, J.M, Kjer-Nielsen, L, Konstenko, L, Purcell, A.W, McCluskey, J, Rossjohn, J. | | 登録日 | 2005-08-03 | | 公開日 | 2005-10-11 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide
Nat.Immunol., 6, 2005
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7MP3
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1MJ5
 | | LINB (haloalkane dehalogenase) from sphingomonas paucimobilis UT26 at atomic resolution | | 分子名称: | 1,3,4,6-tetrachloro-1,4-cyclohexadiene hydrolase, CHLORIDE ION, MAGNESIUM ION | | 著者 | Oakley, A.J, Damborsky, J, Wilce, M.C. | | 登録日 | 2002-08-27 | | 公開日 | 2003-08-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | | 主引用文献 | Crystal structure of haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26 at 0.95 A resolution: dynamics of catalytic residues.
Biochemistry, 43, 2004
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1JLW
 | | Anopheles dirus species B glutathione S-transferases 1-4 | | 分子名称: | glutathione transferase GST1-4 | | 著者 | Oakley, A.J, Harnnoi, T, Udomsinprasert, R, Jirajaroenrat, K, Ketterman, A.J, Wilce, M.C. | | 登録日 | 2001-07-16 | | 公開日 | 2002-07-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | The crystal structures of glutathione S-transferases isozymes 1-3 and 1-4 from Anopheles dirus species B.
Protein Sci., 10, 2001
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1JLV
 | | Anopheles dirus species B glutathione S-transferases 1-3 | | 分子名称: | GLUTATHIONE, glutathione transferase GST1-3 | | 著者 | Oakley, A.J, Harnnoi, T, Udomsinprasert, R, Jirajaroenrat, K, Ketterman, A.J, Wilce, M.C. | | 登録日 | 2001-07-16 | | 公開日 | 2002-07-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | The crystal structures of glutathione S-transferases isozymes 1-3 and 1-4 from Anopheles dirus species B.
Protein Sci., 10, 2001
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5D0J
 | | Grb7 SH2 with inhibitor peptide | | 分子名称: | G7-TEdFP peptide, Growth factor receptor-bound protein 7, PHOSPHATE ION | | 著者 | Gunzburg, M.J, Watson, G.M, Wilce, J.A, Wilce, M.C.J. | | 登録日 | 2015-08-03 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
Sci Rep, 6, 2016
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7S5A
 | | Crystal structure of human chemokine CCL8 | | 分子名称: | C-C motif chemokine 8 | | 著者 | Bhusal, R.P, Devkota, S.R, Aryal, P, Wilce, M.C.J, Stone, M.J. | | 登録日 | 2021-09-10 | | 公開日 | 2021-09-29 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | Structure-guided engineering of tick evasins for targeting chemokines in inflammatory diseases.
Proc.Natl.Acad.Sci.USA, 119, 2022
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4TZG
 | | Crystal structure of eCGP123, an extremely thermostable green fluorescent protein | | 分子名称: | Fluorescent Protein | | 著者 | Close, D.W, Don Paul, C, Traore, D.A.K, Wilce, M.C.J, Prescott, M, Bradbury, A.R.M. | | 登録日 | 2014-07-10 | | 公開日 | 2014-10-22 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Thermal green protein, an extremely stable, nonaggregating fluorescent protein created by structure-guided surface engineering.
Proteins, 83, 2015
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5EEQ
 | | Grb7 SH2 with the G7-B1 bicyclic peptide inhibitor | | 分子名称: | Bicyclic Peptide Inhibitor, Growth factor receptor-bound protein 7, PHOSPHATE ION | | 著者 | Ambaye, N.D, Watson, G.M, Wilce, M.C.J, Wilce, G.M. | | 登録日 | 2015-10-23 | | 公開日 | 2016-06-15 | | 最終更新日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
Sci Rep, 6, 2016
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8SKK
 | | Crystal Structure of the Tick Evasin EVA-AAM1001(L39P) Complexed to Human Chemokine CCL17 | | 分子名称: | C-C motif chemokine 17, Evasin P1243 | | 著者 | Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J. | | 登録日 | 2023-04-19 | | 公開日 | 2023-05-03 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure of the Tick Evasin EVA-AAM1001(L39P) Complexed to Human Chemokine CCL7
To be Published
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5EEL
 | | Grb7 SH2 with bicyclic peptide inhibitor | | 分子名称: | Bicyclic Peptide Inhibitor, FORMIC ACID, Growth factor receptor-bound protein 7, ... | | 著者 | Watson, G.M, Gunzburg, M.J, Wilce, M.C.J, Wilce, J.A. | | 登録日 | 2015-10-23 | | 公開日 | 2016-06-15 | | 最終更新日 | 2018-12-26 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
Sci Rep, 6, 2016
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6APW
 | | Crystal structure of Staphylococcus aureus biotin protein ligase in complex with inhibitor | | 分子名称: | 4-[(4-{5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentyl}-1H-1,2,3-triazol-1-yl)methyl]benzoic acid, Bifunctional ligase/repressor BirA | | 著者 | Cini, D.A, Wilce, M.C.J. | | 登録日 | 2017-08-18 | | 公開日 | 2018-02-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.614 Å) | | 主引用文献 | Halogenation of Biotin Protein Ligase Inhibitors Improves Whole Cell Activity against Staphylococcus aureus.
ACS Infect Dis, 4, 2018
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6AQQ
 | | Crystal structure of Staphylococcus aureus biotin protein ligase in complex with inhibitor | | 分子名称: | (3aS,4S,6aR)-4-(5-{1-[(3-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl}pentyl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one, Bifunctional ligase/repressor BirA | | 著者 | Cini, D.A, Wilce, M.C.J. | | 登録日 | 2017-08-21 | | 公開日 | 2018-02-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Halogenation of Biotin Protein Ligase Inhibitors Improves Whole Cell Activity against Staphylococcus aureus.
ACS Infect Dis, 4, 2018
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5U1Q
 | | Grb7-SH2 with bicyclic peptide inhibitor | | 分子名称: | CHLORIDE ION, Growth factor receptor-bound protein 7, LYS-PHE-GLU-GLY-TYR-ASP-ASN-GLU-CST | | 著者 | Watson, G.M, Wilce, M.C.J, Wilce, J.A. | | 登録日 | 2016-11-28 | | 公開日 | 2017-11-15 | | 最終更新日 | 2020-01-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Discovery, Development, and Cellular Delivery of Potent and Selective Bicyclic Peptide Inhibitors of Grb7 Cancer Target.
J. Med. Chem., 60, 2017
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5TYI
 | | Grb7 SH2 with bicyclic peptide containing pY mimetic | | 分子名称: | Growth factor receptor-bound protein 7, Peptide inhibitor | | 著者 | Watson, G.M, Wilce, M.C.J, Wilce, J.A. | | 登録日 | 2016-11-20 | | 公開日 | 2017-11-15 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Discovery, Development, and Cellular Delivery of Potent and Selective Bicyclic Peptide Inhibitors of Grb7 Cancer Target.
J. Med. Chem., 60, 2017
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1T3W
 | | Crystal Structure of the E.coli DnaG C-terminal domain (residues 434 to 581) | | 分子名称: | ACETIC ACID, DNA primase | | 著者 | Oakley, A.J, Loscha, K.V, Schaeffer, P.M, Liepinsh, E, Wilce, M.C.J, Otting, G, Dixon, N.E. | | 登録日 | 2004-04-28 | | 公開日 | 2004-11-02 | | 最終更新日 | 2016-09-28 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal and solution structures of the helicase-binding domain of Escherichia coli primase
J.Biol.Chem., 280, 2005
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1RH9
 | | Family GH5 endo-beta-mannanase from Lycopersicon esculentum (tomato) | | 分子名称: | endo-beta-mannanase | | 著者 | Oakley, A.J, Bourgault, R, Bewley, J.D, Wilce, M.C.J. | | 登録日 | 2003-11-14 | | 公開日 | 2005-04-19 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Three-dimensional structure of (1,4)-beta-D-mannan mannanohydrolase from tomato fruit.
Protein Sci., 14, 2005
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8FK6
 | | Crystal Structure of the Tick Evasin EVA-AAM1001(Y44A) Complexed to Human Chemokine CCL7 | | 分子名称: | C-C motif chemokine 7, Evasin P1243 | | 著者 | Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J. | | 登録日 | 2022-12-20 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins.
Nat Commun, 14, 2023
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1F4K
 | | CRYSTAL STRUCTURE OF THE REPLICATION TERMINATOR PROTEIN/B-SITE DNA COMPLEX | | 分子名称: | 5'-D(*CP*TP*AP*TP*GP*AP*AP*CP*AP*TP*AP*AP*TP*GP*TP*TP*CP*AP*TP*AP*G)-3', 5'-D(*CP*TP*AP*TP*GP*AP*AP*CP*AP*TP*TP*AP*TP*GP*TP*TP*CP*AP*TP*AP*G)-3', REPLICATION TERMINATION PROTEIN | | 著者 | Wilce, J.A, Vivian, J.P, Hastings, A.F, Otting, G, Folmer, R.H.A, Duggin, I.G, Wake, R.G, Wilce, M.C.J. | | 登録日 | 2000-06-08 | | 公開日 | 2001-06-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of the RTP-DNA complex and the mechanism of polar replication fork arrest
Nat.Struct.Biol., 8, 2001
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2DPU
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2DPD
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2EFW
 | | Crystal structure of the RTP:nRB complex from Bacillus subtilis | | 分子名称: | DNA (5'-D(*DCP*DT*DAP*DTP*DGP*DTP*DAP*DCP*DCP*DAP*DAP*DAP*DTP*DGP*DTP*DTP*DCP*DAP*DGP*DTP*DC)-3'), DNA (5'-D(*DGP*DAP*DCP*DTP*DGP*DAP*DAP*DCP*DAP*DTP*DTP*DTP*DGP*DGP*DTP*DAP*DCP*DAP*DTP*DAP*DG)-3'), Replication termination protein | | 著者 | Vivian, J.P, Porter, C.J, Wilce, J.A, Wilce, M.C.J. | | 登録日 | 2007-02-26 | | 公開日 | 2008-02-26 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | An asymmetric structure of the Bacillus subtilis replication terminator protein in complex with DNA
J.Mol.Biol., 370, 2007
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2DQR
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1ZTG
 | | human alpha polyC binding protein KH1 | | 分子名称: | 5'-D(P*CP*CP*CP*TP*CP*CP*CP*T)-3', POLY(RC)-BINDING PROTEIN 1 | | 著者 | Sidiqi, M, Wilce, J.A, Barker, A, Schmidgerger, J, Leedman, P.J, Wilce, M.C.J. | | 登録日 | 2005-05-27 | | 公開日 | 2006-05-27 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Contribution of the first K-homology domain of poly(C)-binding protein 1 to its affinity and specificity for C-rich oligonucleotides
Nucleic Acids Res., 40, 2012
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