7MP3
Grb7-SH2 domain in complex with bicyclic peptide B8
Summary for 7MP3
| Entry DOI | 10.2210/pdb7mp3/pdb |
| Descriptor | Growth factor receptor-bound protein 7, bicyclic peptide B8 (3 entities in total) |
| Functional Keywords | grb7, sh2, bicyclic-peptide, inhibitor, signaling protein |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 6 |
| Total formula weight | 57575.83 |
| Authors | Colson, R.,Wilce, M.C.J.,Wilce, J.A. (deposition date: 2021-05-04, release date: 2022-02-02, Last modification date: 2024-04-17) |
| Primary citation | Sturre, N.P.,Colson, R.N.,Shah, N.,Watson, G.M.,Yang, X.,Wilce, M.C.J.,Price, J.T.,Wilce, J.A. Enhancing the Bioactivity of Bicyclic Peptides Targeted to Grb7-SH2 by Restoring Cell Permeability. Biomedicines, 10:-, 2022 Cited by PubMed: 35625882DOI: 10.3390/biomedicines10051145 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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