1KSI
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![BU of 1ksi by Molmil](/molmil-images/mine/1ksi) | CRYSTAL STRUCTURE OF A EUKARYOTIC (PEA SEEDLING) COPPER-CONTAINING AMINE OXIDASE AT 2.2A RESOLUTION | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ... | Authors: | Wilce, M.C.J, Kumar, V, Freeman, H.C, Guss, J.M. | Deposit date: | 1996-07-20 | Release date: | 1997-12-24 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a eukaryotic (pea seedling) copper-containing amine oxidase at 2.2 A resolution. Structure, 4, 1996
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8ENI
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![BU of 8eni by Molmil](/molmil-images/mine/8eni) | Crystal structure of Staphylococcus aureus biotin protein ligase in complex with inhibitor | Descriptor: | 3-[4-(5-fluoro-4-{5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentyl}-1H-1,2,3-triazol-1-yl)butyl]-5-methyl-1,3-benzoxazol-2(3H)-one, Bifunctional ligase/repressor BirA | Authors: | Wilce, M.C.J, Cini, D.A. | Deposit date: | 2022-09-30 | Release date: | 2022-11-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Halogenation of Biotin Protein Ligase Inhibitors Improves Whole Cell Activity against Staphylococcus aureus. ACS Infect Dis, 4, 2018
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4DQ2
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![BU of 4dq2 by Molmil](/molmil-images/mine/4dq2) | Structure of staphylococcus aureus biotin protein ligase in complex with biotinol-5'-amp | Descriptor: | ((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHYL 5-((3AS,4S,6AR)-2-OXO-HEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL)PENTYL HYDROGEN PHOSPHATE, Biotin-[acetyl-CoA-carboxylase] ligase | Authors: | Wilce, M, Yap, M, Pendini, N, Soares de Costa, T, Polyak, S, Tieu, W, Booker, G, Wallace, J. | Deposit date: | 2012-02-14 | Release date: | 2012-04-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Selective inhibition of biotin protein ligase from Staphylococcus aureus. J.Biol.Chem., 287, 2012
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1A16
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![BU of 1a16 by Molmil](/molmil-images/mine/1a16) | AMINOPEPTIDASE P FROM E. COLI WITH THE INHIBITOR PRO-LEU | Descriptor: | AMINOPEPTIDASE P, LEUCINE, MANGANESE (II) ION, ... | Authors: | Wilce, M.C, Bond, C.S, Lilley, P.E, Dixon, N.E, Freeman, H.C, Guss, J.M. | Deposit date: | 1997-12-22 | Release date: | 1999-04-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and mechanism of a proline-specific aminopeptidase from Escherichia coli. Proc.Natl.Acad.Sci.USA, 95, 1998
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1WVN
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![BU of 1wvn by Molmil](/molmil-images/mine/1wvn) | |
3RKW
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![BU of 3rkw by Molmil](/molmil-images/mine/3rkw) | |
3RKY
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![BU of 3rky by Molmil](/molmil-images/mine/3rky) | |
3RKX
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![BU of 3rkx by Molmil](/molmil-images/mine/3rkx) | |
1AV4
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![BU of 1av4 by Molmil](/molmil-images/mine/1av4) | |
1AVK
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![BU of 1avk by Molmil](/molmil-images/mine/1avk) | CRYSTAL STRUCTURES OF THE COPPER-CONTAINING AMINE OXIDASE FROM ARTHROBACTER GLOBIFORMIS IN THE HOLO-AND APO-FORMS: IMPLICATIONS FOR THE BIOGENESIS OF TOPA QUINONE | Descriptor: | AMINE OXIDASE | Authors: | Wilce, M.C.J, Guss, J.M, Freeman, H.C, Tanizawa, K, Yamaguchi, H. | Deposit date: | 1997-09-16 | Release date: | 1998-03-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of the copper-containing amine oxidase from Arthrobacter globiformis in the holo and apo forms: implications for the biogenesis of topaquinone. Biochemistry, 36, 1997
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1AVL
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![BU of 1avl by Molmil](/molmil-images/mine/1avl) | |
1JAW
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![BU of 1jaw by Molmil](/molmil-images/mine/1jaw) | AMINOPEPTIDASE P FROM E. COLI LOW PH FORM | Descriptor: | ACETATE ION, AMINOPEPTIDASE P, MANGANESE (II) ION | Authors: | Wilce, M.C.J, Bond, C.S, Lilley, P.E, Dixon, N.E, Freeman, H.C, Guss, J.M. | Deposit date: | 1997-12-22 | Release date: | 1999-04-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure and mechanism of a proline-specific aminopeptidase from Escherichia coli. Proc.Natl.Acad.Sci.USA, 95, 1998
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3RIR
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![BU of 3rir by Molmil](/molmil-images/mine/3rir) | |
1FS0
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![BU of 1fs0 by Molmil](/molmil-images/mine/1fs0) | |
6ORU
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![BU of 6oru by Molmil](/molmil-images/mine/6oru) | |
5ITH
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![BU of 5ith by Molmil](/molmil-images/mine/5ith) | |
7MP3
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![BU of 7mp3 by Molmil](/molmil-images/mine/7mp3) | |
4WWQ
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![BU of 4wwq by Molmil](/molmil-images/mine/4wwq) | Apo structure of the Grb7 SH2 domain | Descriptor: | Growth factor receptor-bound protein 7, MALONIC ACID | Authors: | Watson, G.M, Ambaye, N.D, Wilce, M.C, Wilce, J.A. | Deposit date: | 2014-11-12 | Release date: | 2015-09-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target. J.Med.Chem., 58, 2015
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4X6S
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![BU of 4x6s by Molmil](/molmil-images/mine/4x6s) | Grb7 SH2 domain with phosphotyrosine mimetic inhibitor peptide | Descriptor: | Growth factor receptor-bound protein 7, Phosphotyrosine mimetic inhibitor peptide G7-TEM1 | Authors: | Watson, G.M, Panjikar, S, Wilce, M.C, Wilce, J.A. | Deposit date: | 2014-12-09 | Release date: | 2015-09-23 | Last modified: | 2015-10-28 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target. J.Med.Chem., 58, 2015
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2EFW
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![BU of 2efw by Molmil](/molmil-images/mine/2efw) | Crystal structure of the RTP:nRB complex from Bacillus subtilis | Descriptor: | DNA (5'-D(*DCP*DT*DAP*DTP*DGP*DTP*DAP*DCP*DCP*DAP*DAP*DAP*DTP*DGP*DTP*DTP*DCP*DAP*DGP*DTP*DC)-3'), DNA (5'-D(*DGP*DAP*DCP*DTP*DGP*DAP*DAP*DCP*DAP*DTP*DTP*DTP*DGP*DGP*DTP*DAP*DCP*DAP*DTP*DAP*DG)-3'), Replication termination protein | Authors: | Vivian, J.P, Porter, C.J, Wilce, J.A, Wilce, M.C.J. | Deposit date: | 2007-02-26 | Release date: | 2008-02-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | An asymmetric structure of the Bacillus subtilis replication terminator protein in complex with DNA J.Mol.Biol., 370, 2007
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5EEQ
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![BU of 5eeq by Molmil](/molmil-images/mine/5eeq) | Grb7 SH2 with the G7-B1 bicyclic peptide inhibitor | Descriptor: | Bicyclic Peptide Inhibitor, Growth factor receptor-bound protein 7, PHOSPHATE ION | Authors: | Ambaye, N.D, Watson, G.M, Wilce, M.C.J, Wilce, G.M. | Deposit date: | 2015-10-23 | Release date: | 2016-06-15 | Last modified: | 2024-04-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7. Sci Rep, 6, 2016
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5EEL
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![BU of 5eel by Molmil](/molmil-images/mine/5eel) | Grb7 SH2 with bicyclic peptide inhibitor | Descriptor: | Bicyclic Peptide Inhibitor, FORMIC ACID, Growth factor receptor-bound protein 7, ... | Authors: | Watson, G.M, Gunzburg, M.J, Wilce, M.C.J, Wilce, J.A. | Deposit date: | 2015-10-23 | Release date: | 2016-06-15 | Last modified: | 2018-12-26 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7. Sci Rep, 6, 2016
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2DPU
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![BU of 2dpu by Molmil](/molmil-images/mine/2dpu) | |
2DPD
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![BU of 2dpd by Molmil](/molmil-images/mine/2dpd) | |
2DQR
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![BU of 2dqr by Molmil](/molmil-images/mine/2dqr) | |