Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 379 件
2QB7
DownloadVisualize
BU of 2qb7 by Molmil
Saccharomyces cerevisiae cytosolic exopolyphosphatase, phosphate complex
分子名称: 1,2-ETHANEDIOL, ACETATE ION, COBALT (II) ION, ...
著者White, S.A, Ugochukwu, E.
登録日2007-06-16
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The crystal structure of the cytosolic exopolyphosphatase from Saccharomyces cerevisiae reveals the basis for substrate specificity.
J.Mol.Biol., 371, 2007
7Q0O
DownloadVisualize
BU of 7q0o by Molmil
E. coli NfsA
分子名称: FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NADPH nitroreductase
著者White, S.A, Grainger, A, Parr, R, Day, M.A, Jarrom, D, Graziano, A, Searle, P.F, Hyde, E.I.
登録日2021-10-15
公開日2022-06-22
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (0.96 Å)
主引用文献The 3D-structure, kinetics and dynamics of the E. coli nitroreductase NfsA with NADP + provide glimpses of its catalytic mechanism.
Febs Lett., 596, 2022
7P3H
DownloadVisualize
BU of 7p3h by Molmil
Peptide HC02 - Lanthanide Selectivity Engineered into Structurally Characterized Designed Coiled Coils
分子名称: Peptide HC02, TERBIUM(III) ION, ZINC ION
著者White, S.A, Peacock, A.F.A.
登録日2021-07-07
公開日2021-09-15
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Location-Dependent Lanthanide Selectivity Engineered into Structurally Characterized Designed Coiled Coils.
Angew.Chem.Int.Ed.Engl., 60, 2021
8GDT
DownloadVisualize
BU of 8gdt by Molmil
Heligmosomoides polygyrus TGF-beta Mimic 6 Domain 3 (TGM6-D3) Bound to Human TGF-beta Type II Receptor Extracellular Domain
分子名称: CACODYLATE ION, CHLORIDE ION, GLYCEROL, ...
著者White, S.E, Schwartze, T.A, Hinck, A.P.
登録日2023-03-06
公開日2024-09-11
実験手法X-RAY DIFFRACTION (1.401 Å)
主引用文献Heligmosomoides polygyrus TGF-beta Mimic 6 Domain 3 (TGM6-D3) Bound to Human TGF-beta Type II Receptor Extracellular Domain
To Be Published
7Z0W
DownloadVisualize
BU of 7z0w by Molmil
E. coli NfsA bound to NADP+
分子名称: 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, MAGNESIUM ION, ...
著者White, S.A, Grainger, A, Parr, R, Day, M.A, Jarrom, D, Graziano, A, Searle, P.F, Hyde, E.I.
登録日2022-02-23
公開日2022-07-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献The 3D-structure, kinetics and dynamics of the E. coli nitroreductase NfsA with NADP + provide glimpses of its catalytic mechanism.
Febs Lett., 596, 2022
3FIQ
DownloadVisualize
BU of 3fiq by Molmil
Odorant Binding Protein OBP1
分子名称: 1,2-ETHANEDIOL, Odorant-binding protein 1F
著者White, S.A.
登録日2008-12-12
公開日2009-05-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献Structure of rat odorant-binding protein OBP1 at 1.6 A resolution
Acta Crystallogr.,Sect.D, 65, 2009
6GOX
DownloadVisualize
BU of 6gox by Molmil
SecA
分子名称: Protein translocase subunit SecA
著者White, S.A, Huber, D.
登録日2018-06-04
公開日2019-06-19
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The C-terminal tail of the bacterial translocation ATPase SecA modulates its activity.
Elife, 8, 2019
7UER
DownloadVisualize
BU of 7uer by Molmil
PANK3 complex structure with compound PZ-4071
分子名称: 1,2-ETHANEDIOL, ACETATE ION, MAGNESIUM ION, ...
著者White, S.W, Yun, M, Lee, R.E.
登録日2022-03-22
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published
7UEQ
DownloadVisualize
BU of 7ueq by Molmil
PANK3 complex structure with compound PZ-4061
分子名称: 1-[4-(6-chloropyridazin-3-yl)piperazin-1-yl]-2-[4-(dimethylamino)phenyl]ethan-1-one, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者White, S.W, Yun, M, Lee, R.E.
登録日2022-03-22
公開日2023-03-29
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Development of Brain Penetrant Pyridazine Pantothenate Kinase Activators.
J.Med.Chem., 67, 2024
7UEY
DownloadVisualize
BU of 7uey by Molmil
PANK3 complex structure with compound PZ-4128
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, N-(4-{2-[4-(6-chloropyridazin-3-yl)piperazin-1-yl]-2-oxoethyl}phenyl)-2-hydroxyacetamide, ...
著者White, S.W, Yun, M, Lee, R.E.
登録日2022-03-22
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published
7UE6
DownloadVisualize
BU of 7ue6 by Molmil
PANK3 complex structure with compound PZ-3802
分子名称: 1,2-ETHANEDIOL, 6-(4-{[5-fluoro-6-(propan-2-yl)pyridin-3-yl]acetyl}piperazin-1-yl)pyridazine-3-carbonitrile, ACETATE ION, ...
著者White, S.W, Yun, M, Lee, R.E.
登録日2022-03-21
公開日2023-04-05
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Development of Brain Penetrant Pyridazine Pantothenate Kinase Activators.
J.Med.Chem., 67, 2024
7UEX
DownloadVisualize
BU of 7uex by Molmil
PANK3 complex structure with compound PZ-4127
分子名称: 1,2-ETHANEDIOL, 2-(4-{2-[4-(6-chloropyridazin-3-yl)piperazin-1-yl]-2-oxoethyl}anilino)-2-oxoethyl acetate, ACETATE ION, ...
著者White, S.W, Yun, M, Lee, R.E.
登録日2022-03-22
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published
7UES
DownloadVisualize
BU of 7ues by Molmil
PANK3 complex structure with compound PZ-4202
分子名称: MAGNESIUM ION, N-(4-{2-[4-(6-cyanopyridazin-3-yl)piperazin-1-yl]-2-oxoethyl}phenyl)methanesulfonamide, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者White, S.W, Yun, M, Lee, R.E.
登録日2022-03-22
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published
7UEV
DownloadVisualize
BU of 7uev by Molmil
PANK3 complex structure with compound PZ-4200
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ...
著者White, S.W, Yun, M, Lee, R.E.
登録日2022-03-22
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published
7UET
DownloadVisualize
BU of 7uet by Molmil
PANK3 complex structure with compound PZ-4140
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, N-(4-{2-[4-(6-chloropyridazin-3-yl)piperazin-1-yl]-2-oxoethyl}phenyl)methanesulfonamide, ...
著者White, S.W, Yun, M, Lee, R.E.
登録日2022-03-22
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published
7UEU
DownloadVisualize
BU of 7ueu by Molmil
PANK3 complex structure with compound PZ-4215
分子名称: 1,2-ETHANEDIOL, AMP PHOSPHORAMIDATE, MAGNESIUM ION, ...
著者White, S.W, Yun, M, Lee, R.E.
登録日2022-03-22
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published
6X4J
DownloadVisualize
BU of 6x4j by Molmil
PANK3 complex structure with compound PZ-2863
分子名称: 1,2-ETHANEDIOL, 6-(4-{[4-(propan-2-yl)phenyl]acetyl}piperazin-1-yl)pyridine-3-carbonitrile, MAGNESIUM ION, ...
著者White, S.W, Yun, M.
登録日2020-05-22
公開日2021-11-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献LipE guided discovery of isopropylphenyl pyridazines as pantothenate kinase modulators.
Bioorg.Med.Chem., 52, 2021
6X4L
DownloadVisualize
BU of 6x4l by Molmil
PANK3 complex structure with compound PZ-3565
分子名称: 1,2-ETHANEDIOL, 1-[4-(5-chloropyrazin-2-yl)piperazin-1-yl]-2-[4-(propan-2-yl)phenyl]ethan-1-one, CHLORIDE ION, ...
著者White, S.W, Yun, M.
登録日2020-05-22
公開日2021-11-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献LipE guided discovery of isopropylphenyl pyridazines as pantothenate kinase modulators.
Bioorg.Med.Chem., 52, 2021
6X4K
DownloadVisualize
BU of 6x4k by Molmil
PANK3 complex structure with compound PZ-2890
分子名称: 1,2-ETHANEDIOL, 4-(6-cyanopyridazin-3-yl)-N-[4-(propan-2-yl)phenyl]-3,4-dihydropyrazine-1(2H)-carboxamide, CHLORIDE ION, ...
著者White, S.W, Yun, M.
登録日2020-05-22
公開日2021-11-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献LipE guided discovery of isopropylphenyl pyridazines as pantothenate kinase modulators.
Bioorg.Med.Chem., 52, 2021
7TTD
DownloadVisualize
BU of 7ttd by Molmil
Tubulin-RB3_SLD in complex with compound 12e
分子名称: 7-methoxy-4-[2-(morpholin-4-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-3,4-dihydroquinoxalin-2(1H)-one, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者White, S.W, Yun, M.
登録日2022-02-01
公開日2023-04-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Design, Synthesis, and Biological Evaluation of Pyrimidine Dihydroquinoxalinone Derivatives as Tubulin Colchicine Site-Binding Agents That Displayed Potent Anticancer Activity Both In Vitro and In Vivo.
Acs Pharmacol Transl Sci, 6, 2023
7TTF
DownloadVisualize
BU of 7ttf by Molmil
Tubulin-RB3_SLD in complex with compound 12k
分子名称: 7-methoxy-4-[2-(methylamino)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-3,4-dihydroquinoxalin-2(1H)-one, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ...
著者White, S.W, Yun, M.
登録日2022-02-01
公開日2023-04-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Design, Synthesis, and Biological Evaluation of Pyrimidine Dihydroquinoxalinone Derivatives as Tubulin Colchicine Site-Binding Agents That Displayed Potent Anticancer Activity Both In Vitro and In Vivo.
Acs Pharmacol Transl Sci, 6, 2023
7TTE
DownloadVisualize
BU of 7tte by Molmil
Tubulin-RB3_SLD in complex with compound 12j
分子名称: 4-[2-(cyclopropylamino)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-7-methoxy-3,4-dihydroquinoxalin-2(1H)-one, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者White, S.W, Yun, M.
登録日2022-02-01
公開日2023-04-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Design, Synthesis, and Biological Evaluation of Pyrimidine Dihydroquinoxalinone Derivatives as Tubulin Colchicine Site-Binding Agents That Displayed Potent Anticancer Activity Both In Vitro and In Vivo.
Acs Pharmacol Transl Sci, 6, 2023
8DIQ
DownloadVisualize
BU of 8diq by Molmil
Tubulin-RB3_SLD-TTL in complex with SB226
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-[2-(ethylamino)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-7-methoxy-3,4-dihydroquinoxalin-2(1H)-one, CALCIUM ION, ...
著者White, S.W, Yun, M.
登録日2022-06-29
公開日2023-01-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.395 Å)
主引用文献SB226, an inhibitor of tubulin polymerization, inhibits paclitaxel-resistant melanoma growth and spontaneous metastasis.
Cancer Lett., 555, 2022
1ELH
DownloadVisualize
BU of 1elh by Molmil
NMR ANALYSIS OF HELIX I FROM THE 5S RNA OF ESCHERICHIA COLI
分子名称: RNA (5'-R(*AP*AP*CP*UP*GP*CP*CP*AP*GP*GP*CP*AP*U)-3'), RNA (5'-R(*UP*UP*GP*CP*CP*UP*GP*GP*CP*GP*GP*C)-3')
著者White, S, Moore, P.
登録日1993-06-23
公開日1994-01-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR analysis of helix I from the 5S RNA of Escherichia coli.
Biochemistry, 31, 1992
6XER
DownloadVisualize
BU of 6xer by Molmil
Tubulin-RB3_SLD in complex with colchicine
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者White, S.W, Yun, M.
登録日2020-06-13
公開日2021-08-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Design, Synthesis, and Biological Evaluation of Stable Colchicine-Binding Site Tubulin Inhibitors 6-Aryl-2-benzoyl-pyridines as Potential Anticancer Agents.
J.Med.Chem., 64, 2021

226707

件を2024-10-30に公開中

PDB statisticsPDBj update infoContact PDBjnumon