8IW5
| Crystal structure of liprin-beta H2H3 dimer | 分子名称: | CALCIUM ION, Liprin-beta-1 | 著者 | Zhang, J, Chen, S, Wei, Z. | 登録日 | 2023-03-29 | 公開日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | KANK1 shapes focal adhesions by orchestrating protein binding, mechanical force sensing, and phase separation. Cell Rep, 42, 2023
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8IW0
| Crystal structure of the KANK1/liprin-beta1 complex | 分子名称: | Liprin-beta-1,KN motif and ankyrin repeat domain-containing protein 1 | 著者 | Zhang, J, Chen, S, Wei, Z, Yu, C. | 登録日 | 2023-03-29 | 公開日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | KANK1 shapes focal adhesions by orchestrating protein binding, mechanical force sensing, and phase separation. Cell Rep, 42, 2023
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5XQ1
| Structural basis of kindlin-mediated integrin recognition and activation | 分子名称: | Fermitin family homolog 2,Integrin beta-3 | 著者 | Li, H, Yang, H, Sun, K, Zhang, Z, Yu, C, Wei, Z. | 登録日 | 2017-06-05 | 公開日 | 2017-07-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.954 Å) | 主引用文献 | Structural basis of kindlin-mediated integrin recognition and activation Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5XPY
| Structural basis of kindlin-mediated integrin recognition and activation | 分子名称: | ACETATE ION, Fermitin family homolog 2, GLYCEROL | 著者 | Li, H, Yang, H, Sun, K, Zhang, Z, Yu, C, Wei, Z. | 登録日 | 2017-06-05 | 公開日 | 2017-07-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | 主引用文献 | Structural basis of kindlin-mediated integrin recognition and activation Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5XPZ
| Structural basis of kindlin-mediated integrin recognition and activation | 分子名称: | Fermitin family homolog 2, GLYCEROL | 著者 | Li, H, Yang, H, Sun, K, Zhang, Z, Yu, C, Wei, Z. | 登録日 | 2017-06-05 | 公開日 | 2017-07-26 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.601 Å) | 主引用文献 | Structural basis of kindlin-mediated integrin recognition and activation Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5XQ0
| Structural basis of kindlin-mediated integrin recognition and activation | 分子名称: | Fermitin family homolog 2,Integrin beta-1, GLYCEROL | 著者 | Li, H, Yang, H, Sun, K, Zhang, Z, Yu, C, Wei, Z. | 登録日 | 2017-06-05 | 公開日 | 2017-07-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural basis of kindlin-mediated integrin recognition and activation Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6KR4
| Crystal structure of the liprin-alpha3_SAM123/LAR_D1D2 complex | 分子名称: | HEXAETHYLENE GLYCOL, Liprin-alpha-3, PHOSPHATE ION, ... | 著者 | Xie, X, Liang, M, Luo, L, Wei, Z. | 登録日 | 2019-08-20 | 公開日 | 2020-01-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structural basis of liprin-alpha-promoted LAR-RPTP clustering for modulation of phosphatase activity. Nat Commun, 11, 2020
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8CYI
| Cryo-EM structures and computational analysis for enhanced potency in MTA-synergic inhibition of human protein arginine methyltransferase 5 | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, Methylosome protein 50, N-[(2-aminoquinolin-7-yl)methyl]-9-(2-hydroxyethyl)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamide, ... | 著者 | Yadav, G.P, Wei, Z, Xiaozhi, Y, Chenglong, L, Jiang, Q. | 登録日 | 2022-05-23 | 公開日 | 2023-04-12 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Cryo-EM structure-based selection of computed ligand poses enables design of MTA-synergic PRMT5 inhibitors of better potency. Commun Biol, 5, 2022
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7Y8W
| Crystal structure of DLC-1/SAO-1 complex | 分子名称: | Dynein light chain 1, cytoplasmic, GLYCEROL, ... | 著者 | Yan, H, Zhao, C, Wei, Z, Yu, C. | 登録日 | 2022-06-24 | 公開日 | 2023-07-26 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Interaction between DLC-1 and SAO-1 facilitates CED-4 translocation during apoptosis in the Caenorhabditis elegans germline. Cell Death Discov, 8, 2022
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6C1R
| Crystal structure of human C5a receptor in complex with an orthosteric antagonist PMX53 and an allosteric antagonist avacopan | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, MALONATE ION, OLEIC ACID, ... | 著者 | Liu, H, Wang, L, Wei, Z, Zhang, C. | 登録日 | 2018-01-05 | 公開日 | 2018-05-30 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Orthosteric and allosteric action of the C5a receptor antagonists. Nat. Struct. Mol. Biol., 25, 2018
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6C1Q
| Crystal structure of human C5a receptor in complex with an orthosteric antagonist PMX53 and an allosteric antagonist NDT9513727 | 分子名称: | 1-(1,3-benzodioxol-5-yl)-~{N}-(1,3-benzodioxol-5-ylmethyl)-~{N}-[(3-butyl-2,5-diphenyl-imidazol-4-yl)methyl]methanamine, PMX53, Soluble cytochrome b562, ... | 著者 | Liu, H, Wang, L, Wei, Z, Zhang, C. | 登録日 | 2018-01-05 | 公開日 | 2018-05-30 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Orthosteric and allosteric action of the C5a receptor antagonists. Nat. Struct. Mol. Biol., 25, 2018
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5Y4E
| Crystal Structure of AnkB Ankyrin Repeats R8-14 in complex with autoinhibition segment AI-b | 分子名称: | Ankyrin-2,Ankyrin-2, GLYCEROL, SULFATE ION | 著者 | Chen, K, Li, J, Wang, C, Wei, Z, Zhang, M. | 登録日 | 2017-08-03 | 公開日 | 2017-09-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.341 Å) | 主引用文献 | Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions. Elife, 6, 2017
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5Y4D
| Crystal Structure of AnkB Ankyrin Repeats in Complex with AnkR/AnkB Chimeric Autoinhibition Segment | 分子名称: | Ankyrin-1,Ankyrin-2,Ankyrin-2, SULFATE ION | 著者 | Chen, K, Li, J, Wang, C, Wei, Z, Zhang, M. | 登録日 | 2017-08-03 | 公開日 | 2017-09-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions. Elife, 6, 2017
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5Y4F
| Crystal Structure of AnkB Ankyrin Repeats R13-24 in complex with autoinhibition segment AI-c | 分子名称: | ACETATE ION, Ankyrin-2, CALCIUM ION | 著者 | Chen, K, Li, J, Wang, C, Wei, Z, Zhang, M. | 登録日 | 2017-08-03 | 公開日 | 2017-09-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.953 Å) | 主引用文献 | Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions. Elife, 6, 2017
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4AFX
| Crystal structure of the reactive loop cleaved ZPI in I2 space group | 分子名称: | CALCIUM ION, PHOSPHATE ION, PROTEIN Z DEPENDENT PROTEASE INHIBITOR, ... | 著者 | Zhou, A, Yan, Y, Wei, Z. | 登録日 | 2012-01-23 | 公開日 | 2013-01-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Structural Basis for Catalytic Activation of Protein Z-Dependent Protease Inhibitor (Zpi) by Protein Z. Blood, 120, 2012
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4AJU
| Crystal structure of the reactive loop cleaved ZPI in P41 space group | 分子名称: | 1,2-ETHANEDIOL, PROTEIN Z-DEPENDENT PROTEASE INHIBITOR, SULFATE ION | 著者 | Zhou, A, Yan, Y, Wei, Z. | 登録日 | 2012-02-19 | 公開日 | 2013-01-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structural Basis for Catalytic Activation of Protein Z-Dependent Protease Inhibitor (Zpi) by Protein Z. Blood, 120, 2012
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7D2T
| Crystal structure of Rsu1/PINCH1_LIM45C complex | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, LIM and senescent cell antigen-like-containing domain protein 1, ... | 著者 | Yang, H, Wei, Z, Yu, C. | 登録日 | 2020-09-17 | 公開日 | 2021-02-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics. Elife, 10, 2021
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7D2S
| Crystal structure of Rsu1/PINCH1_LIM5C complex | 分子名称: | GLYCEROL, LIM and senescent cell antigen-like-containing domain protein 1, Ras suppressor protein 1, ... | 著者 | Yang, H, Wei, Z, Cong, Y. | 登録日 | 2020-09-17 | 公開日 | 2021-02-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.653 Å) | 主引用文献 | Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics. Elife, 10, 2021
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7D2U
| Crystal structure of Rsu1/PINCH1_LIM45C complex | 分子名称: | GLYCEROL, LIM and senescent cell antigen-like-containing domain protein 1, MALONATE ION, ... | 著者 | Yang, H, Wei, Z, Cong, Y. | 登録日 | 2020-09-17 | 公開日 | 2021-02-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics. Elife, 10, 2021
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7D2E
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7D2H
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7D2G
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7DDX
| Crystal structure of KANK1 S1179F mutant in complex wtih eIF4A1 | 分子名称: | Eukaryotic initiation factor 4A-I, GLYCEROL, KN motif and ankyrin repeat domains 1, ... | 著者 | Pan, W, Xu, Y, Wei, Z. | 登録日 | 2020-10-30 | 公開日 | 2021-09-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Nephrotic-syndrome-associated mutation of KANK2 induces pathologic binding competition with physiological interactor KIF21A. J.Biol.Chem., 297, 2021
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7YV9
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2HNK
| Crystal structure of SAM-dependent O-methyltransferase from pathogenic bacterium Leptospira interrogans | 分子名称: | DI(HYDROXYETHYL)ETHER, S-ADENOSYL-L-HOMOCYSTEINE, SAM-dependent O-methyltransferase, ... | 著者 | Hou, X, Wei, Z, Gong, W. | 登録日 | 2006-07-13 | 公開日 | 2007-09-04 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of SAM-dependent O-methyltransferase from pathogenic bacterium Leptospira interrogans. J.Struct.Biol., 159, 2007
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