7YV9

Cryo-EM structure of full-length Myosin Va in the autoinhibited state

Summary for 7YV9

• Entry DOI: 10.2210/pdb7yv9/pdb
• EMDB information: 34121
• Descriptor: Unconventional myosin-Va, Calmodulin-1 (2 entities in total)
• Functional Keywords: intracellular trafficking, molecular motor, myosin, autoinhibition, motor protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 16
• Total formula weight: 1052812.70

Authors

Niu, F.,Wei, Z. (deposition date: 2022-08-19, release date: 2022-12-21)

• Primary citation: Niu, F.,Liu, Y.,Sun, K.,Xu, S.,Dong, J.,Yu, C.,Yan, K.,Wei, Z.; Autoinhibition and activation mechanisms revealed by the triangular-shaped structure of myosin Va.; Sci Adv, 8:eadd4187-eadd4187, 2022; PubMed: 36490350; DOI: 10.1126/sciadv.add4187

Experimental method

ELECTRON MICROSCOPY (4.78 Å)