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7YV9

Cryo-EM structure of full-length Myosin Va in the autoinhibited state

Functional Information from GO Data
ChainGOidnamespacecontents
A0000146molecular_functionmicrofilament motor activity
A0000166molecular_functionnucleotide binding
A0001750cellular_componentphotoreceptor outer segment
A0003774molecular_functioncytoskeletal motor activity
A0003779molecular_functionactin binding
A0005509molecular_functioncalcium ion binding
A0005515molecular_functionprotein binding
A0005516molecular_functioncalmodulin binding
A0005524molecular_functionATP binding
A0005737cellular_componentcytoplasm
A0005790cellular_componentsmooth endoplasmic reticulum
A0005794cellular_componentGolgi apparatus
A0005829cellular_componentcytosol
A0005882cellular_componentintermediate filament
A0006582biological_processmelanin metabolic process
A0006887biological_processexocytosis
A0006897biological_processendocytosis
A0007015biological_processactin filament organization
A0007268biological_processchemical synaptic transmission
A0007601biological_processvisual perception
A0015031biological_processprotein transport
A0015629cellular_componentactin cytoskeleton
A0016020cellular_componentmembrane
A0016192biological_processvesicle-mediated transport
A0016459cellular_componentmyosin complex
A0016461cellular_componentunconventional myosin complex
A0016887molecular_functionATP hydrolysis activity
A0018958biological_processphenol-containing compound metabolic process
A0019899molecular_functionenzyme binding
A0030048biological_processactin filament-based movement
A0030050biological_processvesicle transport along actin filament
A0030073biological_processinsulin secretion
A0030141cellular_componentsecretory granule
A0030318biological_processmelanocyte differentiation
A0031267molecular_functionsmall GTPase binding
A0031987biological_processlocomotion involved in locomotory behavior
A0032252biological_processsecretory granule localization
A0032400biological_processmelanosome localization
A0032402biological_processmelanosome transport
A0032593cellular_componentinsulin-responsive compartment
A0032869biological_processcellular response to insulin stimulus
A0042438biological_processmelanin biosynthetic process
A0042470cellular_componentmelanosome
A0042476biological_processodontogenesis
A0042552biological_processmyelination
A0042641cellular_componentactomyosin
A0042759biological_processlong-chain fatty acid biosynthetic process
A0042802molecular_functionidentical protein binding
A0043025cellular_componentneuronal cell body
A0043473biological_processpigmentation
A0048066biological_processdevelopmental pigmentation
A0048820biological_processhair follicle maturation
A0050808biological_processsynapse organization
A0051015molecular_functionactin filament binding
A0051643biological_processendoplasmic reticulum localization
A0072659biological_processprotein localization to plasma membrane
A0097718molecular_functiondisordered domain specific binding
A0098794cellular_componentpostsynapse
A0098978cellular_componentglutamatergic synapse
A0099089biological_processestablishment of endoplasmic reticulum localization to postsynapse
A0099566biological_processregulation of postsynaptic cytosolic calcium ion concentration
B0000086biological_processG2/M transition of mitotic cell cycle
B0000922cellular_componentspindle pole
B0001975biological_processresponse to amphetamine
B0002027biological_processregulation of heart rate
B0005246molecular_functioncalcium channel regulator activity
B0005509molecular_functioncalcium ion binding
B0005513biological_processdetection of calcium ion
B0005515molecular_functionprotein binding
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005813cellular_componentcentrosome
B0005819cellular_componentspindle
B0005829cellular_componentcytosol
B0005856cellular_componentcytoskeleton
B0005876cellular_componentspindle microtubule
B0005929cellular_componentcilium
B0006897biological_processendocytosis
B0008076cellular_componentvoltage-gated potassium channel complex
B0008179molecular_functionadenylate cyclase binding
B0010856molecular_functionadenylate cyclase activator activity
B0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
B0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
B0016240biological_processautophagosome membrane docking
B0019855molecular_functioncalcium channel inhibitor activity
B0019901molecular_functionprotein kinase binding
B0019904molecular_functionprotein domain specific binding
B0030017cellular_componentsarcomere
B0030235molecular_functionnitric-oxide synthase regulator activity
B0030426cellular_componentgrowth cone
B0030672cellular_componentsynaptic vesicle membrane
B0031432molecular_functiontitin binding
B0031514cellular_componentmotile cilium
B0031800molecular_functiontype 3 metabotropic glutamate receptor binding
B0031966cellular_componentmitochondrial membrane
B0032465biological_processregulation of cytokinesis
B0032991cellular_componentprotein-containing complex
B0034704cellular_componentcalcium channel complex
B0035458biological_processcellular response to interferon-beta
B0042995cellular_componentcell projection
B0043209cellular_componentmyelin sheath
B0043539molecular_functionprotein serine/threonine kinase activator activity
B0043548molecular_functionphosphatidylinositol 3-kinase binding
B0044305cellular_componentcalyx of Held
B0044325molecular_functiontransmembrane transporter binding
B0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
B0046872molecular_functionmetal ion binding
B0048306molecular_functioncalcium-dependent protein binding
B0050998molecular_functionnitric-oxide synthase binding
B0051412biological_processresponse to corticosterone
B0051592biological_processresponse to calcium ion
B0051649biological_processestablishment of localization in cell
B0055117biological_processregulation of cardiac muscle contraction
B0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
B0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
B0071346biological_processcellular response to type II interferon
B0072542molecular_functionprotein phosphatase activator activity
B0090150biological_processestablishment of protein localization to membrane
B0090151biological_processestablishment of protein localization to mitochondrial membrane
B0097225cellular_componentsperm midpiece
B0097720biological_processcalcineurin-mediated signaling
B0098685cellular_componentSchaffer collateral - CA1 synapse
B0098901biological_processregulation of cardiac muscle cell action potential
B0099523cellular_componentpresynaptic cytosol
B0099524cellular_componentpostsynaptic cytosol
B0140056biological_processorganelle localization by membrane tethering
B0140238biological_processpresynaptic endocytosis
B0150034cellular_componentdistal axon
B1900242biological_processregulation of synaptic vesicle endocytosis
B1902494cellular_componentcatalytic complex
B1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
B2000300biological_processregulation of synaptic vesicle exocytosis
C0000086biological_processG2/M transition of mitotic cell cycle
C0000922cellular_componentspindle pole
C0001975biological_processresponse to amphetamine
C0002027biological_processregulation of heart rate
C0005246molecular_functioncalcium channel regulator activity
C0005509molecular_functioncalcium ion binding
C0005513biological_processdetection of calcium ion
C0005515molecular_functionprotein binding
C0005654cellular_componentnucleoplasm
C0005737cellular_componentcytoplasm
C0005739cellular_componentmitochondrion
C0005813cellular_componentcentrosome
C0005819cellular_componentspindle
C0005829cellular_componentcytosol
C0005856cellular_componentcytoskeleton
C0005876cellular_componentspindle microtubule
C0005929cellular_componentcilium
C0006897biological_processendocytosis
C0008076cellular_componentvoltage-gated potassium channel complex
C0008179molecular_functionadenylate cyclase binding
C0010856molecular_functionadenylate cyclase activator activity
C0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
C0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
C0016240biological_processautophagosome membrane docking
C0019855molecular_functioncalcium channel inhibitor activity
C0019901molecular_functionprotein kinase binding
C0019904molecular_functionprotein domain specific binding
C0030017cellular_componentsarcomere
C0030235molecular_functionnitric-oxide synthase regulator activity
C0030426cellular_componentgrowth cone
C0030672cellular_componentsynaptic vesicle membrane
C0031432molecular_functiontitin binding
C0031514cellular_componentmotile cilium
C0031800molecular_functiontype 3 metabotropic glutamate receptor binding
C0031966cellular_componentmitochondrial membrane
C0032465biological_processregulation of cytokinesis
C0032991cellular_componentprotein-containing complex
C0034704cellular_componentcalcium channel complex
C0035458biological_processcellular response to interferon-beta
C0042995cellular_componentcell projection
C0043209cellular_componentmyelin sheath
C0043539molecular_functionprotein serine/threonine kinase activator activity
C0043548molecular_functionphosphatidylinositol 3-kinase binding
C0044305cellular_componentcalyx of Held
C0044325molecular_functiontransmembrane transporter binding
C0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
C0046872molecular_functionmetal ion binding
C0048306molecular_functioncalcium-dependent protein binding
C0050998molecular_functionnitric-oxide synthase binding
C0051412biological_processresponse to corticosterone
C0051592biological_processresponse to calcium ion
C0051649biological_processestablishment of localization in cell
C0055117biological_processregulation of cardiac muscle contraction
C0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
C0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
C0071346biological_processcellular response to type II interferon
C0072542molecular_functionprotein phosphatase activator activity
C0090150biological_processestablishment of protein localization to membrane
C0090151biological_processestablishment of protein localization to mitochondrial membrane
C0097225cellular_componentsperm midpiece
C0097720biological_processcalcineurin-mediated signaling
C0098685cellular_componentSchaffer collateral - CA1 synapse
C0098901biological_processregulation of cardiac muscle cell action potential
C0099523cellular_componentpresynaptic cytosol
C0099524cellular_componentpostsynaptic cytosol
C0140056biological_processorganelle localization by membrane tethering
C0140238biological_processpresynaptic endocytosis
C0150034cellular_componentdistal axon
C1900242biological_processregulation of synaptic vesicle endocytosis
C1902494cellular_componentcatalytic complex
C1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
C2000300biological_processregulation of synaptic vesicle exocytosis
D0000086biological_processG2/M transition of mitotic cell cycle
D0000922cellular_componentspindle pole
D0001975biological_processresponse to amphetamine
D0002027biological_processregulation of heart rate
D0005246molecular_functioncalcium channel regulator activity
D0005509molecular_functioncalcium ion binding
D0005513biological_processdetection of calcium ion
D0005515molecular_functionprotein binding
D0005654cellular_componentnucleoplasm
D0005737cellular_componentcytoplasm
D0005739cellular_componentmitochondrion
D0005813cellular_componentcentrosome
D0005819cellular_componentspindle
D0005829cellular_componentcytosol
D0005856cellular_componentcytoskeleton
D0005876cellular_componentspindle microtubule
D0005929cellular_componentcilium
D0006897biological_processendocytosis
D0008076cellular_componentvoltage-gated potassium channel complex
D0008179molecular_functionadenylate cyclase binding
D0010856molecular_functionadenylate cyclase activator activity
D0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
D0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
D0016240biological_processautophagosome membrane docking
D0019855molecular_functioncalcium channel inhibitor activity
D0019901molecular_functionprotein kinase binding
D0019904molecular_functionprotein domain specific binding
D0030017cellular_componentsarcomere
D0030235molecular_functionnitric-oxide synthase regulator activity
D0030426cellular_componentgrowth cone
D0030672cellular_componentsynaptic vesicle membrane
D0031432molecular_functiontitin binding
D0031514cellular_componentmotile cilium
D0031800molecular_functiontype 3 metabotropic glutamate receptor binding
D0031966cellular_componentmitochondrial membrane
D0032465biological_processregulation of cytokinesis
D0032991cellular_componentprotein-containing complex
D0034704cellular_componentcalcium channel complex
D0035458biological_processcellular response to interferon-beta
D0042995cellular_componentcell projection
D0043209cellular_componentmyelin sheath
D0043539molecular_functionprotein serine/threonine kinase activator activity
D0043548molecular_functionphosphatidylinositol 3-kinase binding
D0044305cellular_componentcalyx of Held
D0044325molecular_functiontransmembrane transporter binding
D0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
D0046872molecular_functionmetal ion binding
D0048306molecular_functioncalcium-dependent protein binding
D0050998molecular_functionnitric-oxide synthase binding
D0051412biological_processresponse to corticosterone
D0051592biological_processresponse to calcium ion
D0051649biological_processestablishment of localization in cell
D0055117biological_processregulation of cardiac muscle contraction
D0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
D0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
D0071346biological_processcellular response to type II interferon
D0072542molecular_functionprotein phosphatase activator activity
D0090150biological_processestablishment of protein localization to membrane
D0090151biological_processestablishment of protein localization to mitochondrial membrane
D0097225cellular_componentsperm midpiece
D0097720biological_processcalcineurin-mediated signaling
D0098685cellular_componentSchaffer collateral - CA1 synapse
D0098901biological_processregulation of cardiac muscle cell action potential
D0099523cellular_componentpresynaptic cytosol
D0099524cellular_componentpostsynaptic cytosol
D0140056biological_processorganelle localization by membrane tethering
D0140238biological_processpresynaptic endocytosis
D0150034cellular_componentdistal axon
D1900242biological_processregulation of synaptic vesicle endocytosis
D1902494cellular_componentcatalytic complex
D1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
D2000300biological_processregulation of synaptic vesicle exocytosis
E0000086biological_processG2/M transition of mitotic cell cycle
E0000922cellular_componentspindle pole
E0001975biological_processresponse to amphetamine
E0002027biological_processregulation of heart rate
E0005246molecular_functioncalcium channel regulator activity
E0005509molecular_functioncalcium ion binding
E0005513biological_processdetection of calcium ion
E0005515molecular_functionprotein binding
E0005654cellular_componentnucleoplasm
E0005737cellular_componentcytoplasm
E0005739cellular_componentmitochondrion
E0005813cellular_componentcentrosome
E0005819cellular_componentspindle
E0005829cellular_componentcytosol
E0005856cellular_componentcytoskeleton
E0005876cellular_componentspindle microtubule
E0005929cellular_componentcilium
E0006897biological_processendocytosis
E0008076cellular_componentvoltage-gated potassium channel complex
E0008179molecular_functionadenylate cyclase binding
E0010856molecular_functionadenylate cyclase activator activity
E0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
E0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
E0016240biological_processautophagosome membrane docking
E0019855molecular_functioncalcium channel inhibitor activity
E0019901molecular_functionprotein kinase binding
E0019904molecular_functionprotein domain specific binding
E0030017cellular_componentsarcomere
E0030235molecular_functionnitric-oxide synthase regulator activity
E0030426cellular_componentgrowth cone
E0030672cellular_componentsynaptic vesicle membrane
E0031432molecular_functiontitin binding
E0031514cellular_componentmotile cilium
E0031800molecular_functiontype 3 metabotropic glutamate receptor binding
E0031966cellular_componentmitochondrial membrane
E0032465biological_processregulation of cytokinesis
E0032991cellular_componentprotein-containing complex
E0034704cellular_componentcalcium channel complex
E0035458biological_processcellular response to interferon-beta
E0042995cellular_componentcell projection
E0043209cellular_componentmyelin sheath
E0043539molecular_functionprotein serine/threonine kinase activator activity
E0043548molecular_functionphosphatidylinositol 3-kinase binding
E0044305cellular_componentcalyx of Held
E0044325molecular_functiontransmembrane transporter binding
E0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
E0046872molecular_functionmetal ion binding
E0048306molecular_functioncalcium-dependent protein binding
E0050998molecular_functionnitric-oxide synthase binding
E0051412biological_processresponse to corticosterone
E0051592biological_processresponse to calcium ion
E0051649biological_processestablishment of localization in cell
E0055117biological_processregulation of cardiac muscle contraction
E0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
E0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
E0071346biological_processcellular response to type II interferon
E0072542molecular_functionprotein phosphatase activator activity
E0090150biological_processestablishment of protein localization to membrane
E0090151biological_processestablishment of protein localization to mitochondrial membrane
E0097225cellular_componentsperm midpiece
E0097720biological_processcalcineurin-mediated signaling
E0098685cellular_componentSchaffer collateral - CA1 synapse
E0098901biological_processregulation of cardiac muscle cell action potential
E0099523cellular_componentpresynaptic cytosol
E0099524cellular_componentpostsynaptic cytosol
E0140056biological_processorganelle localization by membrane tethering
E0140238biological_processpresynaptic endocytosis
E0150034cellular_componentdistal axon
E1900242biological_processregulation of synaptic vesicle endocytosis
E1902494cellular_componentcatalytic complex
E1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
E2000300biological_processregulation of synaptic vesicle exocytosis
F0000086biological_processG2/M transition of mitotic cell cycle
F0000922cellular_componentspindle pole
F0001975biological_processresponse to amphetamine
F0002027biological_processregulation of heart rate
F0005246molecular_functioncalcium channel regulator activity
F0005509molecular_functioncalcium ion binding
F0005513biological_processdetection of calcium ion
F0005515molecular_functionprotein binding
F0005654cellular_componentnucleoplasm
F0005737cellular_componentcytoplasm
F0005739cellular_componentmitochondrion
F0005813cellular_componentcentrosome
F0005819cellular_componentspindle
F0005829cellular_componentcytosol
F0005856cellular_componentcytoskeleton
F0005876cellular_componentspindle microtubule
F0005929cellular_componentcilium
F0006897biological_processendocytosis
F0008076cellular_componentvoltage-gated potassium channel complex
F0008179molecular_functionadenylate cyclase binding
F0010856molecular_functionadenylate cyclase activator activity
F0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
F0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
F0016240biological_processautophagosome membrane docking
F0019855molecular_functioncalcium channel inhibitor activity
F0019901molecular_functionprotein kinase binding
F0019904molecular_functionprotein domain specific binding
F0030017cellular_componentsarcomere
F0030235molecular_functionnitric-oxide synthase regulator activity
F0030426cellular_componentgrowth cone
F0030672cellular_componentsynaptic vesicle membrane
F0031432molecular_functiontitin binding
F0031514cellular_componentmotile cilium
F0031800molecular_functiontype 3 metabotropic glutamate receptor binding
F0031966cellular_componentmitochondrial membrane
F0032465biological_processregulation of cytokinesis
F0032991cellular_componentprotein-containing complex
F0034704cellular_componentcalcium channel complex
F0035458biological_processcellular response to interferon-beta
F0042995cellular_componentcell projection
F0043209cellular_componentmyelin sheath
F0043539molecular_functionprotein serine/threonine kinase activator activity
F0043548molecular_functionphosphatidylinositol 3-kinase binding
F0044305cellular_componentcalyx of Held
F0044325molecular_functiontransmembrane transporter binding
F0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
F0046872molecular_functionmetal ion binding
F0048306molecular_functioncalcium-dependent protein binding
F0050998molecular_functionnitric-oxide synthase binding
F0051412biological_processresponse to corticosterone
F0051592biological_processresponse to calcium ion
F0051649biological_processestablishment of localization in cell
F0055117biological_processregulation of cardiac muscle contraction
F0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
F0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
F0071346biological_processcellular response to type II interferon
F0072542molecular_functionprotein phosphatase activator activity
F0090150biological_processestablishment of protein localization to membrane
F0090151biological_processestablishment of protein localization to mitochondrial membrane
F0097225cellular_componentsperm midpiece
F0097720biological_processcalcineurin-mediated signaling
F0098685cellular_componentSchaffer collateral - CA1 synapse
F0098901biological_processregulation of cardiac muscle cell action potential
F0099523cellular_componentpresynaptic cytosol
F0099524cellular_componentpostsynaptic cytosol
F0140056biological_processorganelle localization by membrane tethering
F0140238biological_processpresynaptic endocytosis
F0150034cellular_componentdistal axon
F1900242biological_processregulation of synaptic vesicle endocytosis
F1902494cellular_componentcatalytic complex
F1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
F2000300biological_processregulation of synaptic vesicle exocytosis
G0000086biological_processG2/M transition of mitotic cell cycle
G0000922cellular_componentspindle pole
G0001975biological_processresponse to amphetamine
G0002027biological_processregulation of heart rate
G0005246molecular_functioncalcium channel regulator activity
G0005509molecular_functioncalcium ion binding
G0005513biological_processdetection of calcium ion
G0005515molecular_functionprotein binding
G0005654cellular_componentnucleoplasm
G0005737cellular_componentcytoplasm
G0005739cellular_componentmitochondrion
G0005813cellular_componentcentrosome
G0005819cellular_componentspindle
G0005829cellular_componentcytosol
G0005856cellular_componentcytoskeleton
G0005876cellular_componentspindle microtubule
G0005929cellular_componentcilium
G0006897biological_processendocytosis
G0008076cellular_componentvoltage-gated potassium channel complex
G0008179molecular_functionadenylate cyclase binding
G0010856molecular_functionadenylate cyclase activator activity
G0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
G0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
G0016240biological_processautophagosome membrane docking
G0019855molecular_functioncalcium channel inhibitor activity
G0019901molecular_functionprotein kinase binding
G0019904molecular_functionprotein domain specific binding
G0030017cellular_componentsarcomere
G0030235molecular_functionnitric-oxide synthase regulator activity
G0030426cellular_componentgrowth cone
G0030672cellular_componentsynaptic vesicle membrane
G0031432molecular_functiontitin binding
G0031514cellular_componentmotile cilium
G0031800molecular_functiontype 3 metabotropic glutamate receptor binding
G0031966cellular_componentmitochondrial membrane
G0032465biological_processregulation of cytokinesis
G0032991cellular_componentprotein-containing complex
G0034704cellular_componentcalcium channel complex
G0035458biological_processcellular response to interferon-beta
G0042995cellular_componentcell projection
G0043209cellular_componentmyelin sheath
G0043539molecular_functionprotein serine/threonine kinase activator activity
G0043548molecular_functionphosphatidylinositol 3-kinase binding
G0044305cellular_componentcalyx of Held
G0044325molecular_functiontransmembrane transporter binding
G0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
G0046872molecular_functionmetal ion binding
G0048306molecular_functioncalcium-dependent protein binding
G0050998molecular_functionnitric-oxide synthase binding
G0051412biological_processresponse to corticosterone
G0051592biological_processresponse to calcium ion
G0051649biological_processestablishment of localization in cell
G0055117biological_processregulation of cardiac muscle contraction
G0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
G0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
G0071346biological_processcellular response to type II interferon
G0072542molecular_functionprotein phosphatase activator activity
G0090150biological_processestablishment of protein localization to membrane
G0090151biological_processestablishment of protein localization to mitochondrial membrane
G0097225cellular_componentsperm midpiece
G0097720biological_processcalcineurin-mediated signaling
G0098685cellular_componentSchaffer collateral - CA1 synapse
G0098901biological_processregulation of cardiac muscle cell action potential
G0099523cellular_componentpresynaptic cytosol
G0099524cellular_componentpostsynaptic cytosol
G0140056biological_processorganelle localization by membrane tethering
G0140238biological_processpresynaptic endocytosis
G0150034cellular_componentdistal axon
G1900242biological_processregulation of synaptic vesicle endocytosis
G1902494cellular_componentcatalytic complex
G1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
G2000300biological_processregulation of synaptic vesicle exocytosis
H0000146molecular_functionmicrofilament motor activity
H0000166molecular_functionnucleotide binding
H0001750cellular_componentphotoreceptor outer segment
H0003774molecular_functioncytoskeletal motor activity
H0003779molecular_functionactin binding
H0005509molecular_functioncalcium ion binding
H0005515molecular_functionprotein binding
H0005516molecular_functioncalmodulin binding
H0005524molecular_functionATP binding
H0005737cellular_componentcytoplasm
H0005790cellular_componentsmooth endoplasmic reticulum
H0005794cellular_componentGolgi apparatus
H0005829cellular_componentcytosol
H0005882cellular_componentintermediate filament
H0006582biological_processmelanin metabolic process
H0006887biological_processexocytosis
H0006897biological_processendocytosis
H0007015biological_processactin filament organization
H0007268biological_processchemical synaptic transmission
H0007601biological_processvisual perception
H0015031biological_processprotein transport
H0015629cellular_componentactin cytoskeleton
H0016020cellular_componentmembrane
H0016192biological_processvesicle-mediated transport
H0016459cellular_componentmyosin complex
H0016461cellular_componentunconventional myosin complex
H0016887molecular_functionATP hydrolysis activity
H0018958biological_processphenol-containing compound metabolic process
H0019899molecular_functionenzyme binding
H0030048biological_processactin filament-based movement
H0030050biological_processvesicle transport along actin filament
H0030073biological_processinsulin secretion
H0030141cellular_componentsecretory granule
H0030318biological_processmelanocyte differentiation
H0031267molecular_functionsmall GTPase binding
H0031987biological_processlocomotion involved in locomotory behavior
H0032252biological_processsecretory granule localization
H0032400biological_processmelanosome localization
H0032402biological_processmelanosome transport
H0032593cellular_componentinsulin-responsive compartment
H0032869biological_processcellular response to insulin stimulus
H0042438biological_processmelanin biosynthetic process
H0042470cellular_componentmelanosome
H0042476biological_processodontogenesis
H0042552biological_processmyelination
H0042641cellular_componentactomyosin
H0042759biological_processlong-chain fatty acid biosynthetic process
H0042802molecular_functionidentical protein binding
H0043025cellular_componentneuronal cell body
H0043473biological_processpigmentation
H0048066biological_processdevelopmental pigmentation
H0048820biological_processhair follicle maturation
H0050808biological_processsynapse organization
H0051015molecular_functionactin filament binding
H0051643biological_processendoplasmic reticulum localization
H0072659biological_processprotein localization to plasma membrane
H0097718molecular_functiondisordered domain specific binding
H0098794cellular_componentpostsynapse
H0098978cellular_componentglutamatergic synapse
H0099089biological_processestablishment of endoplasmic reticulum localization to postsynapse
H0099566biological_processregulation of postsynaptic cytosolic calcium ion concentration
I0000086biological_processG2/M transition of mitotic cell cycle
I0000922cellular_componentspindle pole
I0001975biological_processresponse to amphetamine
I0002027biological_processregulation of heart rate
I0005246molecular_functioncalcium channel regulator activity
I0005509molecular_functioncalcium ion binding
I0005513biological_processdetection of calcium ion
I0005515molecular_functionprotein binding
I0005654cellular_componentnucleoplasm
I0005737cellular_componentcytoplasm
I0005739cellular_componentmitochondrion
I0005813cellular_componentcentrosome
I0005819cellular_componentspindle
I0005829cellular_componentcytosol
I0005856cellular_componentcytoskeleton
I0005876cellular_componentspindle microtubule
I0005929cellular_componentcilium
I0006897biological_processendocytosis
I0008076cellular_componentvoltage-gated potassium channel complex
I0008179molecular_functionadenylate cyclase binding
I0010856molecular_functionadenylate cyclase activator activity
I0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
I0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
I0016240biological_processautophagosome membrane docking
I0019855molecular_functioncalcium channel inhibitor activity
I0019901molecular_functionprotein kinase binding
I0019904molecular_functionprotein domain specific binding
I0030017cellular_componentsarcomere
I0030235molecular_functionnitric-oxide synthase regulator activity
I0030426cellular_componentgrowth cone
I0030672cellular_componentsynaptic vesicle membrane
I0031432molecular_functiontitin binding
I0031514cellular_componentmotile cilium
I0031800molecular_functiontype 3 metabotropic glutamate receptor binding
I0031966cellular_componentmitochondrial membrane
I0032465biological_processregulation of cytokinesis
I0032991cellular_componentprotein-containing complex
I0034704cellular_componentcalcium channel complex
I0035458biological_processcellular response to interferon-beta
I0042995cellular_componentcell projection
I0043209cellular_componentmyelin sheath
I0043539molecular_functionprotein serine/threonine kinase activator activity
I0043548molecular_functionphosphatidylinositol 3-kinase binding
I0044305cellular_componentcalyx of Held
I0044325molecular_functiontransmembrane transporter binding
I0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
I0046872molecular_functionmetal ion binding
I0048306molecular_functioncalcium-dependent protein binding
I0050998molecular_functionnitric-oxide synthase binding
I0051412biological_processresponse to corticosterone
I0051592biological_processresponse to calcium ion
I0051649biological_processestablishment of localization in cell
I0055117biological_processregulation of cardiac muscle contraction
I0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
I0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
I0071346biological_processcellular response to type II interferon
I0072542molecular_functionprotein phosphatase activator activity
I0090150biological_processestablishment of protein localization to membrane
I0090151biological_processestablishment of protein localization to mitochondrial membrane
I0097225cellular_componentsperm midpiece
I0097720biological_processcalcineurin-mediated signaling
I0098685cellular_componentSchaffer collateral - CA1 synapse
I0098901biological_processregulation of cardiac muscle cell action potential
I0099523cellular_componentpresynaptic cytosol
I0099524cellular_componentpostsynaptic cytosol
I0140056biological_processorganelle localization by membrane tethering
I0140238biological_processpresynaptic endocytosis
I0150034cellular_componentdistal axon
I1900242biological_processregulation of synaptic vesicle endocytosis
I1902494cellular_componentcatalytic complex
I1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
I2000300biological_processregulation of synaptic vesicle exocytosis
J0000086biological_processG2/M transition of mitotic cell cycle
J0000922cellular_componentspindle pole
J0001975biological_processresponse to amphetamine
J0002027biological_processregulation of heart rate
J0005246molecular_functioncalcium channel regulator activity
J0005509molecular_functioncalcium ion binding
J0005513biological_processdetection of calcium ion
J0005515molecular_functionprotein binding
J0005654cellular_componentnucleoplasm
J0005737cellular_componentcytoplasm
J0005739cellular_componentmitochondrion
J0005813cellular_componentcentrosome
J0005819cellular_componentspindle
J0005829cellular_componentcytosol
J0005856cellular_componentcytoskeleton
J0005876cellular_componentspindle microtubule
J0005929cellular_componentcilium
J0006897biological_processendocytosis
J0008076cellular_componentvoltage-gated potassium channel complex
J0008179molecular_functionadenylate cyclase binding
J0010856molecular_functionadenylate cyclase activator activity
J0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
J0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
J0016240biological_processautophagosome membrane docking
J0019855molecular_functioncalcium channel inhibitor activity
J0019901molecular_functionprotein kinase binding
J0019904molecular_functionprotein domain specific binding
J0030017cellular_componentsarcomere
J0030235molecular_functionnitric-oxide synthase regulator activity
J0030426cellular_componentgrowth cone
J0030672cellular_componentsynaptic vesicle membrane
J0031432molecular_functiontitin binding
J0031514cellular_componentmotile cilium
J0031800molecular_functiontype 3 metabotropic glutamate receptor binding
J0031966cellular_componentmitochondrial membrane
J0032465biological_processregulation of cytokinesis
J0032991cellular_componentprotein-containing complex
J0034704cellular_componentcalcium channel complex
J0035458biological_processcellular response to interferon-beta
J0042995cellular_componentcell projection
J0043209cellular_componentmyelin sheath
J0043539molecular_functionprotein serine/threonine kinase activator activity
J0043548molecular_functionphosphatidylinositol 3-kinase binding
J0044305cellular_componentcalyx of Held
J0044325molecular_functiontransmembrane transporter binding
J0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
J0046872molecular_functionmetal ion binding
J0048306molecular_functioncalcium-dependent protein binding
J0050998molecular_functionnitric-oxide synthase binding
J0051412biological_processresponse to corticosterone
J0051592biological_processresponse to calcium ion
J0051649biological_processestablishment of localization in cell
J0055117biological_processregulation of cardiac muscle contraction
J0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
J0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
J0071346biological_processcellular response to type II interferon
J0072542molecular_functionprotein phosphatase activator activity
J0090150biological_processestablishment of protein localization to membrane
J0090151biological_processestablishment of protein localization to mitochondrial membrane
J0097225cellular_componentsperm midpiece
J0097720biological_processcalcineurin-mediated signaling
J0098685cellular_componentSchaffer collateral - CA1 synapse
J0098901biological_processregulation of cardiac muscle cell action potential
J0099523cellular_componentpresynaptic cytosol
J0099524cellular_componentpostsynaptic cytosol
J0140056biological_processorganelle localization by membrane tethering
J0140238biological_processpresynaptic endocytosis
J0150034cellular_componentdistal axon
J1900242biological_processregulation of synaptic vesicle endocytosis
J1902494cellular_componentcatalytic complex
J1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
J2000300biological_processregulation of synaptic vesicle exocytosis
K0000086biological_processG2/M transition of mitotic cell cycle
K0000922cellular_componentspindle pole
K0001975biological_processresponse to amphetamine
K0002027biological_processregulation of heart rate
K0005246molecular_functioncalcium channel regulator activity
K0005509molecular_functioncalcium ion binding
K0005513biological_processdetection of calcium ion
K0005515molecular_functionprotein binding
K0005654cellular_componentnucleoplasm
K0005737cellular_componentcytoplasm
K0005739cellular_componentmitochondrion
K0005813cellular_componentcentrosome
K0005819cellular_componentspindle
K0005829cellular_componentcytosol
K0005856cellular_componentcytoskeleton
K0005876cellular_componentspindle microtubule
K0005929cellular_componentcilium
K0006897biological_processendocytosis
K0008076cellular_componentvoltage-gated potassium channel complex
K0008179molecular_functionadenylate cyclase binding
K0010856molecular_functionadenylate cyclase activator activity
K0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
K0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
K0016240biological_processautophagosome membrane docking
K0019855molecular_functioncalcium channel inhibitor activity
K0019901molecular_functionprotein kinase binding
K0019904molecular_functionprotein domain specific binding
K0030017cellular_componentsarcomere
K0030235molecular_functionnitric-oxide synthase regulator activity
K0030426cellular_componentgrowth cone
K0030672cellular_componentsynaptic vesicle membrane
K0031432molecular_functiontitin binding
K0031514cellular_componentmotile cilium
K0031800molecular_functiontype 3 metabotropic glutamate receptor binding
K0031966cellular_componentmitochondrial membrane
K0032465biological_processregulation of cytokinesis
K0032991cellular_componentprotein-containing complex
K0034704cellular_componentcalcium channel complex
K0035458biological_processcellular response to interferon-beta
K0042995cellular_componentcell projection
K0043209cellular_componentmyelin sheath
K0043539molecular_functionprotein serine/threonine kinase activator activity
K0043548molecular_functionphosphatidylinositol 3-kinase binding
K0044305cellular_componentcalyx of Held
K0044325molecular_functiontransmembrane transporter binding
K0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
K0046872molecular_functionmetal ion binding
K0048306molecular_functioncalcium-dependent protein binding
K0050998molecular_functionnitric-oxide synthase binding
K0051412biological_processresponse to corticosterone
K0051592biological_processresponse to calcium ion
K0051649biological_processestablishment of localization in cell
K0055117biological_processregulation of cardiac muscle contraction
K0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
K0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
K0071346biological_processcellular response to type II interferon
K0072542molecular_functionprotein phosphatase activator activity
K0090150biological_processestablishment of protein localization to membrane
K0090151biological_processestablishment of protein localization to mitochondrial membrane
K0097225cellular_componentsperm midpiece
K0097720biological_processcalcineurin-mediated signaling
K0098685cellular_componentSchaffer collateral - CA1 synapse
K0098901biological_processregulation of cardiac muscle cell action potential
K0099523cellular_componentpresynaptic cytosol
K0099524cellular_componentpostsynaptic cytosol
K0140056biological_processorganelle localization by membrane tethering
K0140238biological_processpresynaptic endocytosis
K0150034cellular_componentdistal axon
K1900242biological_processregulation of synaptic vesicle endocytosis
K1902494cellular_componentcatalytic complex
K1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
K2000300biological_processregulation of synaptic vesicle exocytosis
L0000086biological_processG2/M transition of mitotic cell cycle
L0000922cellular_componentspindle pole
L0001975biological_processresponse to amphetamine
L0002027biological_processregulation of heart rate
L0005246molecular_functioncalcium channel regulator activity
L0005509molecular_functioncalcium ion binding
L0005513biological_processdetection of calcium ion
L0005515molecular_functionprotein binding
L0005654cellular_componentnucleoplasm
L0005737cellular_componentcytoplasm
L0005739cellular_componentmitochondrion
L0005813cellular_componentcentrosome
L0005819cellular_componentspindle
L0005829cellular_componentcytosol
L0005856cellular_componentcytoskeleton
L0005876cellular_componentspindle microtubule
L0005929cellular_componentcilium
L0006897biological_processendocytosis
L0008076cellular_componentvoltage-gated potassium channel complex
L0008179molecular_functionadenylate cyclase binding
L0010856molecular_functionadenylate cyclase activator activity
L0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
L0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
L0016240biological_processautophagosome membrane docking
L0019855molecular_functioncalcium channel inhibitor activity
L0019901molecular_functionprotein kinase binding
L0019904molecular_functionprotein domain specific binding
L0030017cellular_componentsarcomere
L0030235molecular_functionnitric-oxide synthase regulator activity
L0030426cellular_componentgrowth cone
L0030672cellular_componentsynaptic vesicle membrane
L0031432molecular_functiontitin binding
L0031514cellular_componentmotile cilium
L0031800molecular_functiontype 3 metabotropic glutamate receptor binding
L0031966cellular_componentmitochondrial membrane
L0032465biological_processregulation of cytokinesis
L0032991cellular_componentprotein-containing complex
L0034704cellular_componentcalcium channel complex
L0035458biological_processcellular response to interferon-beta
L0042995cellular_componentcell projection
L0043209cellular_componentmyelin sheath
L0043539molecular_functionprotein serine/threonine kinase activator activity
L0043548molecular_functionphosphatidylinositol 3-kinase binding
L0044305cellular_componentcalyx of Held
L0044325molecular_functiontransmembrane transporter binding
L0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
L0046872molecular_functionmetal ion binding
L0048306molecular_functioncalcium-dependent protein binding
L0050998molecular_functionnitric-oxide synthase binding
L0051412biological_processresponse to corticosterone
L0051592biological_processresponse to calcium ion
L0051649biological_processestablishment of localization in cell
L0055117biological_processregulation of cardiac muscle contraction
L0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
L0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
L0071346biological_processcellular response to type II interferon
L0072542molecular_functionprotein phosphatase activator activity
L0090150biological_processestablishment of protein localization to membrane
L0090151biological_processestablishment of protein localization to mitochondrial membrane
L0097225cellular_componentsperm midpiece
L0097720biological_processcalcineurin-mediated signaling
L0098685cellular_componentSchaffer collateral - CA1 synapse
L0098901biological_processregulation of cardiac muscle cell action potential
L0099523cellular_componentpresynaptic cytosol
L0099524cellular_componentpostsynaptic cytosol
L0140056biological_processorganelle localization by membrane tethering
L0140238biological_processpresynaptic endocytosis
L0150034cellular_componentdistal axon
L1900242biological_processregulation of synaptic vesicle endocytosis
L1902494cellular_componentcatalytic complex
L1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
L2000300biological_processregulation of synaptic vesicle exocytosis
M0000086biological_processG2/M transition of mitotic cell cycle
M0000922cellular_componentspindle pole
M0001975biological_processresponse to amphetamine
M0002027biological_processregulation of heart rate
M0005246molecular_functioncalcium channel regulator activity
M0005509molecular_functioncalcium ion binding
M0005513biological_processdetection of calcium ion
M0005515molecular_functionprotein binding
M0005654cellular_componentnucleoplasm
M0005737cellular_componentcytoplasm
M0005739cellular_componentmitochondrion
M0005813cellular_componentcentrosome
M0005819cellular_componentspindle
M0005829cellular_componentcytosol
M0005856cellular_componentcytoskeleton
M0005876cellular_componentspindle microtubule
M0005929cellular_componentcilium
M0006897biological_processendocytosis
M0008076cellular_componentvoltage-gated potassium channel complex
M0008179molecular_functionadenylate cyclase binding
M0010856molecular_functionadenylate cyclase activator activity
M0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
M0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
M0016240biological_processautophagosome membrane docking
M0019855molecular_functioncalcium channel inhibitor activity
M0019901molecular_functionprotein kinase binding
M0019904molecular_functionprotein domain specific binding
M0030017cellular_componentsarcomere
M0030235molecular_functionnitric-oxide synthase regulator activity
M0030426cellular_componentgrowth cone
M0030672cellular_componentsynaptic vesicle membrane
M0031432molecular_functiontitin binding
M0031514cellular_componentmotile cilium
M0031800molecular_functiontype 3 metabotropic glutamate receptor binding
M0031966cellular_componentmitochondrial membrane
M0032465biological_processregulation of cytokinesis
M0032991cellular_componentprotein-containing complex
M0034704cellular_componentcalcium channel complex
M0035458biological_processcellular response to interferon-beta
M0042995cellular_componentcell projection
M0043209cellular_componentmyelin sheath
M0043539molecular_functionprotein serine/threonine kinase activator activity
M0043548molecular_functionphosphatidylinositol 3-kinase binding
M0044305cellular_componentcalyx of Held
M0044325molecular_functiontransmembrane transporter binding
M0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
M0046872molecular_functionmetal ion binding
M0048306molecular_functioncalcium-dependent protein binding
M0050998molecular_functionnitric-oxide synthase binding
M0051412biological_processresponse to corticosterone
M0051592biological_processresponse to calcium ion
M0051649biological_processestablishment of localization in cell
M0055117biological_processregulation of cardiac muscle contraction
M0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
M0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
M0071346biological_processcellular response to type II interferon
M0072542molecular_functionprotein phosphatase activator activity
M0090150biological_processestablishment of protein localization to membrane
M0090151biological_processestablishment of protein localization to mitochondrial membrane
M0097225cellular_componentsperm midpiece
M0097720biological_processcalcineurin-mediated signaling
M0098685cellular_componentSchaffer collateral - CA1 synapse
M0098901biological_processregulation of cardiac muscle cell action potential
M0099523cellular_componentpresynaptic cytosol
M0099524cellular_componentpostsynaptic cytosol
M0140056biological_processorganelle localization by membrane tethering
M0140238biological_processpresynaptic endocytosis
M0150034cellular_componentdistal axon
M1900242biological_processregulation of synaptic vesicle endocytosis
M1902494cellular_componentcatalytic complex
M1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
M2000300biological_processregulation of synaptic vesicle exocytosis
N0000086biological_processG2/M transition of mitotic cell cycle
N0000922cellular_componentspindle pole
N0001975biological_processresponse to amphetamine
N0002027biological_processregulation of heart rate
N0005246molecular_functioncalcium channel regulator activity
N0005509molecular_functioncalcium ion binding
N0005513biological_processdetection of calcium ion
N0005515molecular_functionprotein binding
N0005654cellular_componentnucleoplasm
N0005737cellular_componentcytoplasm
N0005739cellular_componentmitochondrion
N0005813cellular_componentcentrosome
N0005819cellular_componentspindle
N0005829cellular_componentcytosol
N0005856cellular_componentcytoskeleton
N0005876cellular_componentspindle microtubule
N0005929cellular_componentcilium
N0006897biological_processendocytosis
N0008076cellular_componentvoltage-gated potassium channel complex
N0008179molecular_functionadenylate cyclase binding
N0010856molecular_functionadenylate cyclase activator activity
N0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
N0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
N0016240biological_processautophagosome membrane docking
N0019855molecular_functioncalcium channel inhibitor activity
N0019901molecular_functionprotein kinase binding
N0019904molecular_functionprotein domain specific binding
N0030017cellular_componentsarcomere
N0030235molecular_functionnitric-oxide synthase regulator activity
N0030426cellular_componentgrowth cone
N0030672cellular_componentsynaptic vesicle membrane
N0031432molecular_functiontitin binding
N0031514cellular_componentmotile cilium
N0031800molecular_functiontype 3 metabotropic glutamate receptor binding
N0031966cellular_componentmitochondrial membrane
N0032465biological_processregulation of cytokinesis
N0032991cellular_componentprotein-containing complex
N0034704cellular_componentcalcium channel complex
N0035458biological_processcellular response to interferon-beta
N0042995cellular_componentcell projection
N0043209cellular_componentmyelin sheath
N0043539molecular_functionprotein serine/threonine kinase activator activity
N0043548molecular_functionphosphatidylinositol 3-kinase binding
N0044305cellular_componentcalyx of Held
N0044325molecular_functiontransmembrane transporter binding
N0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
N0046872molecular_functionmetal ion binding
N0048306molecular_functioncalcium-dependent protein binding
N0050998molecular_functionnitric-oxide synthase binding
N0051412biological_processresponse to corticosterone
N0051592biological_processresponse to calcium ion
N0051649biological_processestablishment of localization in cell
N0055117biological_processregulation of cardiac muscle contraction
N0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
N0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
N0071346biological_processcellular response to type II interferon
N0072542molecular_functionprotein phosphatase activator activity
N0090150biological_processestablishment of protein localization to membrane
N0090151biological_processestablishment of protein localization to mitochondrial membrane
N0097225cellular_componentsperm midpiece
N0097720biological_processcalcineurin-mediated signaling
N0098685cellular_componentSchaffer collateral - CA1 synapse
N0098901biological_processregulation of cardiac muscle cell action potential
N0099523cellular_componentpresynaptic cytosol
N0099524cellular_componentpostsynaptic cytosol
N0140056biological_processorganelle localization by membrane tethering
N0140238biological_processpresynaptic endocytosis
N0150034cellular_componentdistal axon
N1900242biological_processregulation of synaptic vesicle endocytosis
N1902494cellular_componentcatalytic complex
N1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
N2000300biological_processregulation of synaptic vesicle exocytosis
X0000146molecular_functionmicrofilament motor activity
X0000166molecular_functionnucleotide binding
X0001750cellular_componentphotoreceptor outer segment
X0003774molecular_functioncytoskeletal motor activity
X0003779molecular_functionactin binding
X0005509molecular_functioncalcium ion binding
X0005515molecular_functionprotein binding
X0005516molecular_functioncalmodulin binding
X0005524molecular_functionATP binding
X0005737cellular_componentcytoplasm
X0005790cellular_componentsmooth endoplasmic reticulum
X0005794cellular_componentGolgi apparatus
X0005829cellular_componentcytosol
X0005882cellular_componentintermediate filament
X0006582biological_processmelanin metabolic process
X0006887biological_processexocytosis
X0006897biological_processendocytosis
X0007015biological_processactin filament organization
X0007268biological_processchemical synaptic transmission
X0007601biological_processvisual perception
X0015031biological_processprotein transport
X0015629cellular_componentactin cytoskeleton
X0016020cellular_componentmembrane
X0016192biological_processvesicle-mediated transport
X0016459cellular_componentmyosin complex
X0016461cellular_componentunconventional myosin complex
X0016887molecular_functionATP hydrolysis activity
X0018958biological_processphenol-containing compound metabolic process
X0019899molecular_functionenzyme binding
X0030048biological_processactin filament-based movement
X0030050biological_processvesicle transport along actin filament
X0030073biological_processinsulin secretion
X0030141cellular_componentsecretory granule
X0030318biological_processmelanocyte differentiation
X0031267molecular_functionsmall GTPase binding
X0031987biological_processlocomotion involved in locomotory behavior
X0032252biological_processsecretory granule localization
X0032400biological_processmelanosome localization
X0032402biological_processmelanosome transport
X0032593cellular_componentinsulin-responsive compartment
X0032869biological_processcellular response to insulin stimulus
X0042438biological_processmelanin biosynthetic process
X0042470cellular_componentmelanosome
X0042476biological_processodontogenesis
X0042552biological_processmyelination
X0042641cellular_componentactomyosin
X0042759biological_processlong-chain fatty acid biosynthetic process
X0042802molecular_functionidentical protein binding
X0043025cellular_componentneuronal cell body
X0043473biological_processpigmentation
X0048066biological_processdevelopmental pigmentation
X0048820biological_processhair follicle maturation
X0050808biological_processsynapse organization
X0051015molecular_functionactin filament binding
X0051643biological_processendoplasmic reticulum localization
X0072659biological_processprotein localization to plasma membrane
X0097718molecular_functiondisordered domain specific binding
X0098794cellular_componentpostsynapse
X0098978cellular_componentglutamatergic synapse
X0099089biological_processestablishment of endoplasmic reticulum localization to postsynapse
X0099566biological_processregulation of postsynaptic cytosolic calcium ion concentration
Y0000146molecular_functionmicrofilament motor activity
Y0000166molecular_functionnucleotide binding
Y0001750cellular_componentphotoreceptor outer segment
Y0003774molecular_functioncytoskeletal motor activity
Y0003779molecular_functionactin binding
Y0005509molecular_functioncalcium ion binding
Y0005515molecular_functionprotein binding
Y0005516molecular_functioncalmodulin binding
Y0005524molecular_functionATP binding
Y0005737cellular_componentcytoplasm
Y0005790cellular_componentsmooth endoplasmic reticulum
Y0005794cellular_componentGolgi apparatus
Y0005829cellular_componentcytosol
Y0005882cellular_componentintermediate filament
Y0006582biological_processmelanin metabolic process
Y0006887biological_processexocytosis
Y0006897biological_processendocytosis
Y0007015biological_processactin filament organization
Y0007268biological_processchemical synaptic transmission
Y0007601biological_processvisual perception
Y0015031biological_processprotein transport
Y0015629cellular_componentactin cytoskeleton
Y0016020cellular_componentmembrane
Y0016192biological_processvesicle-mediated transport
Y0016459cellular_componentmyosin complex
Y0016461cellular_componentunconventional myosin complex
Y0016887molecular_functionATP hydrolysis activity
Y0018958biological_processphenol-containing compound metabolic process
Y0019899molecular_functionenzyme binding
Y0030048biological_processactin filament-based movement
Y0030050biological_processvesicle transport along actin filament
Y0030073biological_processinsulin secretion
Y0030141cellular_componentsecretory granule
Y0030318biological_processmelanocyte differentiation
Y0031267molecular_functionsmall GTPase binding
Y0031987biological_processlocomotion involved in locomotory behavior
Y0032252biological_processsecretory granule localization
Y0032400biological_processmelanosome localization
Y0032402biological_processmelanosome transport
Y0032593cellular_componentinsulin-responsive compartment
Y0032869biological_processcellular response to insulin stimulus
Y0042438biological_processmelanin biosynthetic process
Y0042470cellular_componentmelanosome
Y0042476biological_processodontogenesis
Y0042552biological_processmyelination
Y0042641cellular_componentactomyosin
Y0042759biological_processlong-chain fatty acid biosynthetic process
Y0042802molecular_functionidentical protein binding
Y0043025cellular_componentneuronal cell body
Y0043473biological_processpigmentation
Y0048066biological_processdevelopmental pigmentation
Y0048820biological_processhair follicle maturation
Y0050808biological_processsynapse organization
Y0051015molecular_functionactin filament binding
Y0051643biological_processendoplasmic reticulum localization
Y0072659biological_processprotein localization to plasma membrane
Y0097718molecular_functiondisordered domain specific binding
Y0098794cellular_componentpostsynapse
Y0098978cellular_componentglutamatergic synapse
Y0099089biological_processestablishment of endoplasmic reticulum localization to postsynapse
Y0099566biological_processregulation of postsynaptic cytosolic calcium ion concentration
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: BINDING => ECO:0000255
ChainResidueDetails
AGLY163
BGLN68
FGLN141
GASP21
GASP23
GASP25
GTHR27
GGLN32
GASP57
GASP59
GASN61
GTHR63
BASP94
GGLN68
GASP94
GASP96
GASN98
GTYR100
GGLN105
GASP130
GASP132
GASP134
GGLN136
BASP96
GGLN141
IASP21
IASP23
IASP25
ITHR27
IGLN32
IASP57
IASP59
IASN61
ITHR63
BASN98
IGLN68
IASP94
IASP96
IASN98
ITYR100
IGLN105
IASP130
IASP132
IASP134
IGLN136
BTYR100
IGLN141
JASP21
JASP23
JASP25
JTHR27
JGLN32
JASP57
JASP59
JASN61
JTHR63
BGLN105
JGLN68
JASP94
JASP96
JASN98
JTYR100
JGLN105
JASP130
JASP132
JASP134
JGLN136
BASP130
JGLN141
KASP21
KASP23
KASP25
KTHR27
KGLN32
KASP57
KASP59
KASN61
KTHR63
BASP132
KGLN68
KASP94
KASP96
KASN98
KTYR100
KGLN105
KASP130
KASP132
KASP134
KGLN136
BASP134
KGLN141
LASP21
LASP23
LASP25
LTHR27
LGLN32
LASP57
LASP59
LASN61
LTHR63
BGLN136
LGLN68
LASP94
LASP96
LASN98
LTYR100
LGLN105
LASP130
LASP132
LASP134
LGLN136
HGLY163
BGLN141
LGLN141
MASP21
MASP23
MASP25
MTHR27
MGLN32
MASP57
MASP59
MASN61
MTHR63
CASP21
MGLN68
MASP94
MASP96
MASN98
MTYR100
MGLN105
MASP130
MASP132
MASP134
MGLN136
CASP23
MGLN141
NASP21
NASP23
NASP25
NTHR27
NGLN32
NASP57
NASP59
NASN61
NTHR63
CASP25
NGLN68
NASP94
NASP96
NASN98
NTYR100
NGLN105
NASP130
NASP132
NASP134
NGLN136
CTHR27
NGLN141
CGLN32
CASP57
CASP59
CASN61
CTHR63
XGLY163
CGLN68
CASP94
CASP96
CASN98
CTYR100
CGLN105
CASP130
CASP132
CASP134
CGLN136
YGLY163
CGLN141
DASP21
DASP23
DASP25
DTHR27
DGLN32
DASP57
DASP59
DASN61
DTHR63
BGLN32
DGLN68
DASP94
DASP96
DASN98
DTYR100
DGLN105
DASP130
DASP132
DASP134
DGLN136
BASP57
DGLN141
EASP21
EASP23
EASP25
ETHR27
EGLN32
EASP57
EASP59
EASN61
ETHR63
BASP59
EGLN68
EASP94
EASP96
EASN98
ETYR100
EGLN105
EASP130
EASP132
EASP134
EGLN136
BASN61
EGLN141
FASP21
FASP23
FASP25
FTHR27
FGLN32
FASP57
FASP59
FASN61
FTHR63
BTHR63
FGLN68
FASP94
FASP96
FASN98
FTYR100
FGLN105
FASP130
FASP132
FASP134
FGLN136

site_idSWS_FT_FI2
Number of Residues4
DetailsMOD_RES: N-acetylalanine => ECO:0000250|UniProtKB:Q9Y4I1
ChainResidueDetails
AALA2
LALA2
MALA2
NALA2
HALA2
XALA2
YALA2
FALA2
GALA2
IALA2
JALA2
KALA2

site_idSWS_FT_FI3
Number of Residues4
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:19144319, ECO:0007744|PubMed:21183079
ChainResidueDetails
ASER600
LLYS22
MLYS22
NLYS22
HSER600
XSER600
YSER600
FLYS22
GLYS22
ILYS22
JLYS22
KLYS22

site_idSWS_FT_FI4
Number of Residues4
DetailsMOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q9QYF3
ChainResidueDetails
ATHR1032
LTHR45
MTHR45
NTHR45
HTHR1032
XTHR1032
YTHR1032
FTHR45
GTHR45
ITHR45
JTHR45
KTHR45

site_idSWS_FT_FI5
Number of Residues8
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:21183079
ChainResidueDetails
ALEU1450
LSER82
MSER82
NSER82
AGLN1650
HLEU1450
HGLN1650
XLEU1450
XGLN1650
YLEU1450
YGLN1650
KSER82

site_idSWS_FT_FI6
Number of Residues4
DetailsMOD_RES: Phosphothreonine => ECO:0000255
ChainResidueDetails
ALEU1758
LLYS95
MLYS95
NLYS95
HLEU1758
XLEU1758
YLEU1758
FLYS95
GLYS95
ILYS95
JLYS95
KLYS95

site_idSWS_FT_FI7
Number of Residues12
DetailsMOD_RES: Phosphotyrosine => ECO:0007744|PubMed:18034455, ECO:0007744|PubMed:21183079
ChainResidueDetails
BTYR100
LTYR100
MTYR100
NTYR100
CTYR100
DTYR100
ETYR100
FTYR100
GTYR100
ITYR100
JTYR100
KTYR100

site_idSWS_FT_FI8
Number of Residues12
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:21183079
ChainResidueDetails
BSER102
LSER102
MSER102
NSER102
CSER102
DSER102
ESER102
FSER102
GSER102
ISER102
JSER102
KSER102

site_idSWS_FT_FI9
Number of Residues12
DetailsMOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P0DP23
ChainResidueDetails
BTHR111
LTHR111
MTHR111
NTHR111
CTHR111
DTHR111
ETHR111
FTHR111
GTHR111
ITHR111
JTHR111
KTHR111

site_idSWS_FT_FI10
Number of Residues12
DetailsMOD_RES: N6-methyllysine; alternate => ECO:0000250|UniProtKB:P0DP23
ChainResidueDetails
BLYS116
LLYS116
MLYS116
NLYS116
CLYS116
DLYS116
ELYS116
FLYS116
GLYS116
ILYS116
JLYS116
KLYS116

site_idSWS_FT_FI11
Number of Residues12
DetailsMOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P0DP23
ChainResidueDetails
BTYR139
LTYR139
MTYR139
NTYR139
CTYR139
DTYR139
ETYR139
FTYR139
GTYR139
ITYR139
JTYR139
KTYR139

site_idSWS_FT_FI12
Number of Residues24
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000250|UniProtKB:P62157
ChainResidueDetails
BLYS22
GLYS22
ILYS22
JLYS22
KLYS22
LLYS22
MLYS22
NLYS22
CLYS22
DLYS22
ELYS22
FLYS22

237423

PDB entries from 2025-06-11

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