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PDB: 86 件

1GG6
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CRYSTAL STRUCTURE OF GAMMA CHYMOTRYPSIN WITH N-ACETYL-PHENYLALANINE TRIFLUOROMETHYL KETONE BOUND AT THE ACTIVE SITE
分子名称: 1,1,1-TRIFLUORO-3-ACETAMIDO-4-PHENYL BUTAN-2-ONE(N-ACETYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE), 1,2-ETHANEDIOL, GAMMA CHYMOTRYPSIN, ...
著者Neidhart, D, Wei, Y, Cassidy, C, Lin, J, Cleland, W.W, Frey, P.A.
登録日2000-07-31
公開日2000-09-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Correlation of low-barrier hydrogen bonding and oxyanion binding in transition state analogue complexes of chymotrypsin.
Biochemistry, 40, 2001
1TIB
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CONFORMATIONAL LABILITY OF LIPASES OBSERVED IN THE ABSENCE OF AN OIL-WATER INTERFACE: CRYSTALLOGRAPHIC STUDIES OF ENZYMES FROM THE FUNGI HUMICOLA LANUGINOSA AND RHIZOPUS DELEMAR
分子名称: LIPASE
著者Derewenda, U, Swenson, L, Wei, Y, Derewenda, Z.S.
登録日1993-12-06
公開日1995-01-26
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Conformational lability of lipases observed in the absence of an oil-water interface: crystallographic studies of enzymes from the fungi Humicola lanuginosa and Rhizopus delemar.
J.Lipid Res., 35, 1994
5GOL
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Structure of acetyl-Coenzyme A synthase Alpha subunit C-terminal domain F598H mutant
分子名称: Carbon monoxide dehydrogenase/acetyl-CoA synthase subunit alpha, NICKEL (II) ION, SULFATE ION
著者Yuan, H, Wei, Y.Z, Tan, X.S.
登録日2016-07-27
公開日2017-09-06
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structure of acetyl-Coenzyme A synthase Alpha subunit C-terminal domain F598H mutant
To Be Published
5MV1
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Crystal structure of the E protein of the Japanese encephalitis virulent virus
分子名称: E protein
著者Liu, X, Zhao, X, Na, R, Li, L, Warkentin, E, Witt, J, Lu, X, Wei, Y, Peng, G, Li, Y, Wang, J.
登録日2017-01-14
公開日2018-05-23
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The structure differences of Japanese encephalitis virus SA14 and SA14-14-2 E proteins elucidate the virulence attenuation mechanism.
Protein Cell, 10, 2019
4XO2
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crystal structure of GnsA from E.coli
分子名称: Protein GnsA
著者Zhan, L.H, Gao, Z.Q, Wei, Y, Dong, Y.H.
登録日2015-01-16
公開日2015-06-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.952 Å)
主引用文献Crystal structure of GnsA from Escherichia coli
Biochem.Biophys.Res.Commun., 462, 2015
4F1R
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Structure analysis of the global metabolic regulator Crc from Pseudomonas aeruginos
分子名称: Catabolite repression control protein
著者Zhang, H, Wei, Y, Gao, Z.Q, Dong, Y.H.
登録日2012-05-07
公開日2013-02-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Structure analysis of the global metabolic regulator Crc from Pseudomonas aeruginosa.
Iubmb Life, 65, 2013
4EEQ
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Crystal structure of E. faecalis DNA ligase with inhibitor
分子名称: 4-amino-2-(cyclopentyloxy)pyrimidine-5-carboxamide, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DNA ligase, ...
著者Wang, T, Charifson, P, Wei, Y.
登録日2012-03-28
公開日2013-04-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Design, Synthesis and Activity Evaluation of Potent NAD+ DNA Ligase Inhibitors as Potential Antibacterial Agents.
To be Published
1TLH
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T4 AsiA bound to sigma70 region 4
分子名称: 10 kDa anti-sigma factor, RNA polymerase sigma factor rpoD
著者Lambert, L.J, Wei, Y, Schirf, V, Demeler, B, Werner, M.H.
登録日2004-06-09
公開日2004-11-23
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献T4 AsiA blocks DNA recognition by remodeling sigma(70) region 4
Embo J., 23, 2004
1THT
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STRUCTURE OF A MYRISTOYL-ACP-SPECIFIC THIOESTERASE FROM VIBRIO HARVEYI
分子名称: THIOESTERASE
著者Lawson, D.M, Derewenda, U, Serre, L, Ferri, S, Szitter, R, Wei, Y, Meighen, E.A, Derewenda, Z.S.
登録日1994-04-19
公開日1995-06-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of a myristoyl-ACP-specific thioesterase from Vibrio harveyi.
Biochemistry, 33, 1994
1TL6
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Solution structure of T4 bacteriphage AsiA monomer
分子名称: 10 kDa anti-sigma factor
著者Lambert, L.J, Wei, Y, Schirf, V, Demeler, B, Werner, M.H.
登録日2004-06-09
公開日2005-06-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献T4 AsiA blocks DNA recognition by remodeling sigma70 region 4
Embo J., 23, 2004
3TKA
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BU of 3tka by Molmil
crystal structure and solution saxs of methyltransferase rsmh from E.coli
分子名称: 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, Ribosomal RNA small subunit methyltransferase H, S-ADENOSYLMETHIONINE, ...
著者Gao, Z.Q, Wei, Y, Zhang, H, Dong, Y.H.
登録日2011-08-25
公開日2012-05-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal and solution structures of methyltransferase RsmH provide basis for methylation of C1402 in 16S rRNA.
J.Struct.Biol., 179, 2012
2GF5
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Structure of intact FADD (MORT1)
分子名称: FADD protein
著者Carrington, P.E, Sandu, C, Wei, Y, Hill, J.M, Morisawa, G, Huang, T, Gavathiotis, E, Wei, Y, Werner, M.H.
登録日2006-03-21
公開日2006-06-27
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The Structure of FADD and Its Mode of Interaction with Procaspase-8
Mol.Cell, 22, 2006
6LGW
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Structure of Rabies virus glycoprotein in complex with neutralizing antibody 523-11 at acidic pH
分子名称: Glycoprotein, scFv 523-11
著者Yang, F.L, Lin, S, Ye, F, Yang, J, Qi, J.X, Chen, Z.J, Lin, X, Wang, J.C, Yue, D, Cheng, Y.W, Chen, Z.M, Chen, H, You, Y, Zhang, Z.L, Yang, Y, Yang, M, Sun, H.L, Li, Y.H, Cao, Y, Yang, S.Y, Wei, Y.Q, Gao, G.F, Lu, G.W.
登録日2019-12-06
公開日2020-02-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.9037 Å)
主引用文献Structural Analysis of Rabies Virus Glycoprotein Reveals pH-Dependent Conformational Changes and Interactions with a Neutralizing Antibody.
Cell Host Microbe, 27, 2020
6LGX
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Structure of Rabies virus glycoprotein at basic pH
分子名称: Glycoprotein,Glycoprotein,Glycoprotein
著者Yang, F.L, Lin, S, Ye, F, Yang, J, Qi, J.X, Chen, Z.J, Lin, X, Wang, J.C, Yue, D, Cheng, Y.W, Chen, Z.M, Chen, H, You, Y, Zhang, Z.L, Yang, Y, Yang, M, Sun, H.L, Li, Y.H, Cao, Y, Yang, S.Y, Wei, Y.Q, Gao, G.F, Lu, G.W.
登録日2019-12-06
公開日2020-02-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.097 Å)
主引用文献Structural Analysis of Rabies Virus Glycoprotein Reveals pH-Dependent Conformational Changes and Interactions with a Neutralizing Antibody.
Cell Host Microbe, 27, 2020
7Y5N
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BU of 7y5n by Molmil
Structure of 1:1 PAPP-A.ProMBP complex(half map)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Bone marrow proteoglycan, ...
著者Zhong, Q.H, Chu, H.L, Wang, G.P, Zhang, C, Wei, Y, Qiao, J, Hang, J.
登録日2022-06-17
公開日2023-01-11
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2.
Cell Discov, 8, 2022
7Y5Q
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Structure of 1:1 PAPP-A.STC2 complex(half map)
分子名称: Maltose/maltodextrin-binding periplasmic protein,Pappalysin-1, Stanniocalcin-2, ZINC ION
著者Zhong, Q.H, Chu, H.L, Wang, G.P, Zhang, C, Wei, Y, Qiao, J, Hang, J.
登録日2022-06-17
公開日2023-01-11
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2.
Cell Discov, 8, 2022
7XLQ
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Structure of human R-type voltage-gated CaV2.3-alpha2/delta1-beta1 channel complex in the ligand-free (apo) state
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Gao, Y, Qiu, Y, Wei, Y, Dong, Y, Zhang, X.C, Zhao, Y.
登録日2022-04-22
公開日2023-02-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Molecular insights into the gating mechanisms of voltage-gated calcium channel Ca V 2.3.
Nat Commun, 14, 2023
6CVZ
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BU of 6cvz by Molmil
Crystal structure of the WD40-repeat of RFWD3
分子名称: E3 ubiquitin-protein ligase RFWD3, MAGNESIUM ION
著者DONG, A, LOPPNAU, P, SEITOVA, A, HUTCHINSON, A, TEMPEL, W, WEI, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, TONG, Y, Structural Genomics Consortium (SGC)
登録日2018-03-29
公開日2018-06-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Target highlights in CASP13: Experimental target structures through the eyes of their authors.
Proteins, 87, 2019
5YMR
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BU of 5ymr by Molmil
The Crystal Structure of IseG
分子名称: 2-hydroxyethylsulfonic acid, Formate acetyltransferase, GLYCEROL
著者Lin, L, Zhang, J, Xing, M, Hua, G, Guo, C, Hu, Y, Wei, Y, Ang, E, Zhao, H, Zhang, Y, Yuchi, Z.
登録日2017-10-22
公開日2019-03-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria.
Nat Commun, 10, 2019
8HGH
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Structure of 2:2 PAPP-A.STC2 complex
分子名称: Maltose/maltodextrin-binding periplasmic protein,Pappalysin-1, Stanniocalcin-2, ZINC ION
著者Zhong, Q.H, Chu, H.L, Wang, G.P, Zhang, C, Wei, Y, Qiao, J, Hang, J.
登録日2022-11-14
公開日2023-01-11
実験手法ELECTRON MICROSCOPY (4.16 Å)
主引用文献Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2.
Cell Discov, 8, 2022
8HGG
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Structure of 2:2 PAPP-A.ProMBP complex
分子名称: Bone marrow proteoglycan, Pappalysin-1, ZINC ION
著者Zhong, Q.H, Chu, H.L, Wang, G.P, Zhang, C, Wei, Y, Qiao, J, Hang, J.
登録日2022-11-14
公開日2023-01-11
実験手法ELECTRON MICROSCOPY (3.64 Å)
主引用文献Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2.
Cell Discov, 8, 2022
7E88
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Crystal structure of the SARS-CoV-2 S RBD in complex with BD-515 Fab
分子名称: BD-515 Fab Heavy Chain, BD-515 Fab Light Chain, Spike protein S1
著者Gao, C, Wei, Y, Xiao, J.
登録日2021-03-01
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
6JHB
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Crystal structure of NADPH and 4-hydroxyphenylpyruvic acid bound AerF from Microcystis aeruginosa
分子名称: 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short chain dehydrogenase family protein
著者Qiu, X, Wei, Y, Zhu, W.
登録日2019-02-17
公開日2019-11-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structural and functional investigation of AerF, a NADPH-dependent alkenal double bond reductase participating in the biosynthesis of Choi moiety of aeruginosin
J.Struct.Biol., 2019
6LM3
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Neutralization mechanism of a monoclonal antibody targeting a porcine circovirus type 2 Cap protein conformational epitope
分子名称: Capsid protein
著者Sun, Z, Huang, L, Xia, D, Wei, Y, Sun, E, Zhu, H, Bian, H, Wu, H, Feng, L, Wang, J, Liu, C.
登録日2019-12-24
公開日2020-02-12
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (6.7 Å)
主引用文献Neutralization Mechanism of a Monoclonal Antibody Targeting a Porcine Circovirus Type 2 Cap Protein Conformational Epitope.
J.Virol., 94, 2020
6L62
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Neutralization mechanism of a monoclonal antibody targeting a porcine circovirus type 2 Cap protein conformational epitope
分子名称: Capsid protein, Heavy chain of Fab fragment, Light chain of Fab fragment
著者Sun, Z, Huang, L, Xia, D, Wei, Y, Sun, E, Zhu, H, Bian, H, Wu, H, Feng, L, Wang, J, Liu, C.
登録日2019-10-25
公開日2020-02-12
最終更新日2020-04-29
実験手法ELECTRON MICROSCOPY (7.2 Å)
主引用文献Neutralization Mechanism of a Monoclonal Antibody Targeting a Porcine Circovirus Type 2 Cap Protein Conformational Epitope.
J.Virol., 94, 2020

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