8HGG

Structure of 2:2 PAPP-A.ProMBP complex

Summary for 8HGG

• Entry DOI: 10.2210/pdb8hgg/pdb
• EMDB information: 34738
• Descriptor: Bone marrow proteoglycan, Pappalysin-1, ZINC ION (3 entities in total)
• Functional Keywords: hydrolase, metal binding protein, complex
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 412955.16

Authors

Zhong, Q.H.,Chu, H.L.,Wang, G.P.,Zhang, C.,Wei, Y.,Qiao, J.,Hang, J. (deposition date: 2022-11-14, release date: 2023-01-11)

• Primary citation: Zhong, Q.,Chu, H.,Wang, G.,Zhang, C.,Li, R.,Guo, F.,Meng, X.,Lei, X.,Zhou, Y.,Ren, R.,Tao, L.,Li, N.,Gao, N.,Wei, Y.,Qiao, J.,Hang, J.; Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2.; Cell Discov, 8:137-137, 2022; PubMed: 36550107; DOI: 10.1038/s41421-022-00502-2

Experimental method

ELECTRON MICROSCOPY (3.64 Å)