7XLQ

Structure of human R-type voltage-gated CaV2.3-alpha2/delta1-beta1 channel complex in the ligand-free (apo) state

Summary for 7XLQ

• Entry DOI: 10.2210/pdb7xlq/pdb
• EMDB information: 33285
• Descriptor: Voltage-dependent R-type calcium channel subunit alpha-1E, 2-acetamido-2-deoxy-beta-D-glucopyranose, Voltage-dependent calcium channel subunit alpha-2/delta-1, ... (10 entities in total)
• Functional Keywords: voltage-gated calcium channel, cav2.3, complex, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 458752.88

Authors

Gao, Y.,Qiu, Y.,Wei, Y.,Dong, Y.,Zhang, X.C.,Zhao, Y. (deposition date: 2022-04-22, release date: 2023-02-08)

• Primary citation: Gao, Y.,Xu, S.,Cui, X.,Xu, H.,Qiu, Y.,Wei, Y.,Dong, Y.,Zhu, B.,Peng, C.,Liu, S.,Zhang, X.C.,Sun, J.,Huang, Z.,Zhao, Y.; Molecular insights into the gating mechanisms of voltage-gated calcium channel Ca V 2.3.; Nat Commun, 14:516-516, 2023; PubMed: 36720859; DOI: 10.1038/s41467-023-36260-2

Experimental method

ELECTRON MICROSCOPY (3.1 Å)