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7XLQ

Structure of human R-type voltage-gated CaV2.3-alpha2/delta1-beta1 channel complex in the ligand-free (apo) state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Voltage-dependent R-type calcium channel subunit alpha-1Epolymer2313262056.01UniProt (Q15878)
Pfam (PF00520)
Pfam (PF08016)
Pfam (PF16905)
Pfam (PF08763)
Homo sapiens (human)Brain calcium channel II,BII,Calcium channel,L type,alpha-1 polypeptide,isoform 6,Voltage-gated calcium channel subunit alpha Cav2.3
2B
(D)
Voltage-dependent calcium channel subunit alpha-2/delta-1polymer1077122034.41UniProt (P54289)
Pfam (PF08399)
Pfam (PF00092)
Pfam (PF08473)
Homo sapiens (human)Voltage-gated calcium channel subunit alpha-2/delta-1
3C
(B)
Voltage-dependent L-type calcium channel subunit beta-1polymer59865799.61UniProt (Q02641)
Pfam (PF00625)
Pfam (PF12052)
Homo sapiens (human)CAB1,Calcium channel voltage-dependent subunit beta 1
4D, E
(C, E)
beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched586.52In PDB
GlyTouCan (G15407YE)
5F
(F)
beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched586.51In PDB
GlyTouCan (G44266EX)
6G, J, L, N, P...
(A)
CHOLESTEROL HEMISUCCINATEnon-polymer486.76Chemie (Y01)
7H, I, K, M, Q...
(A)
HEXADECANEnon-polymer226.47Chemie (R16)
8O
(A)
1,2-Distearoyl-sn-glycerophosphoethanolaminenon-polymer748.11Chemie (3PE)
9AA, S
(D, A)
CALCIUM IONnon-polymer40.12Chemie (CA)
10BA, CA, DA, V, W...
(D)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.28Chemie (NAG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight449889.9
BranchedNumber of molecules3
Total formula weight1759.6
Non-Polymers*Number of molecules24
Total formula weight7103.3
All*Total formula weight458752.9
*Water molecules are not included.

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PDB entries from 2026-01-14

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