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PDB: 121 results

6TC8
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2'-F-arabinoguanosine and 2'-F-riboguanosine modified hybrid type G-quadruplex with V-loop
Descriptor: DNA (5'-D(*GP*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*(GFL)P*(GF2)P*GP*GP*AP*CP*GP*GP*G)-3')
Authors:Haase, L, Weisz, K.
Deposit date:2019-11-05
Release date:2020-03-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Switching the type of V-loop in sugar-modified G-quadruplexes through altered fluorine interactions.
Chem.Commun.(Camb.), 56, 2020
6TCG
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2'-F-riboguanosine and 2'-F-arabinoguanosine modified G-quadruplex with V-loop and all-syn G-tract
Descriptor: DNA (5'-D(*GP*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*(GF2)P*(GFL)P*GP*GP*AP*CP*GP*GP*G)-3')
Authors:Haase, L, Weisz, K.
Deposit date:2019-11-06
Release date:2020-03-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Switching the type of V-loop in sugar-modified G-quadruplexes through altered fluorine interactions.
Chem.Commun.(Camb.), 56, 2020
1E09
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Solution Structure of the Major Cherry Allergen Pru av 1
Descriptor: PRU AV 1
Authors:Neudecker, P, Nerkamp, J, Schweimer, K, Sticht, H, Boehm, M, Scheurer, S, Vieths, S, Roesch, P.
Deposit date:2000-03-15
Release date:2001-03-15
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Allergic Cross-Reactivity Made Visible: The Solution Structure of the Major Cherry Allergen Pru Av 1
J.Biol.Chem., 276, 2001
6TF4
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Solution structure of RfaH C-terminal domain from Vibrio cholerae
Descriptor: Transcription/translation regulatory transformer protein RfaH
Authors:Zuber, P.K, Schweimer, K, Knauer, S.H.
Deposit date:2019-11-13
Release date:2021-11-24
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structural and thermodynamic analyses of the beta-to-alpha transformation in RfaH reveal principles of fold-switching proteins.
Elife, 11, 2022
6RS3
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2'-F-riboguanosine modified G-quadruplex with V-loop
Descriptor: F1415
Authors:Haase, L, Weisz, K.
Deposit date:2019-05-21
Release date:2019-11-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Sugar Puckering Drives G-Quadruplex Refolding: Implications for V-Shaped Loops.
Chemistry, 26, 2020
8A8U
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Mycobacterium tuberculosis ClpC1 hexamer structure
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide
Authors:Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K.
Deposit date:2022-06-24
Release date:2022-10-26
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action.
J.Biol.Chem., 298, 2022
8A8V
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Mycobacterium tuberculosis ClpC1 hexamer structure bound to the natural product antibiotic Cyclomarin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide
Authors:Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K.
Deposit date:2022-06-24
Release date:2022-10-26
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action.
J.Biol.Chem., 298, 2022
8A8W
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Mycobacterium tuberculosis ClpC1 hexamer structure bound to the natural product antibiotic Ecumycin (class 1)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide
Authors:Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K.
Deposit date:2022-06-24
Release date:2022-10-26
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (4.29 Å)
Cite:Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action.
J.Biol.Chem., 298, 2022
8PSE
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(3+1) hybrid G-quadruplex from a G-rich sequence with five G-runs
Descriptor: DNA (5'-D(*AP*GP*GP*GP*TP*AP*GP*GP*GP*CP*GP*GP*CP*GP*(BG)P*GP*TP*AP*CP*GP*GP*GP*T)-3')
Authors:Jana, J, Vianney, Y.M, Schroder, N, Weisz, K.
Deposit date:2023-07-13
Release date:2023-09-27
Last modified:2023-10-18
Method:SOLUTION NMR
Cite:Showcasing Different G-Quadruplex Folds of a G-Rich Sequence: Between Rule-Based Prediction and Butterfly Effect.
J.Am.Chem.Soc., 145, 2023
8PSI
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G-quadruplex with a 1-nt V-shaped loop from a G-rich sequence with five G-runs
Descriptor: DNA (5'-D(*GP*GP*GP*TP*AP*GP*GP*GP*CP*GP*GP*CP*GP*GP*GP*GP*CP*AP*GP*GP*GP*T)-3')
Authors:Vianney, Y.M, Schroeder, N, Jana, J, Weisz, K.
Deposit date:2023-07-13
Release date:2023-09-27
Last modified:2023-10-18
Method:SOLUTION NMR
Cite:Showcasing Different G-Quadruplex Folds of a G-Rich Sequence: Between Rule-Based Prediction and Butterfly Effect.
J.Am.Chem.Soc., 145, 2023
8PSC
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Three-layered basket-type G-quadruplex from a G-rich sequence with five G-runs
Descriptor: DNA (5'-D(*AP*GP*(BG)P*GP*TP*AP*GP*GP*GP*CP*GP*GP*CP*GP*GP*GP*GP*CP*AP*GP*GP*GP*T)-3')
Authors:Vianney, Y.M, Schroeder, N, Jana, J, Weisz, K.
Deposit date:2023-07-13
Release date:2023-09-27
Last modified:2023-10-18
Method:SOLUTION NMR
Cite:Showcasing Different G-Quadruplex Folds of a G-Rich Sequence: Between Rule-Based Prediction and Butterfly Effect.
J.Am.Chem.Soc., 145, 2023
6GQ9
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Solution structure of the hazel allergen Cor a 1.0401
Descriptor: Major allergen Cor a 1.0401
Authors:Jacob, T.P, Schweimer, K, Seutter von Loetzen, C, Woehrl, B.M.
Deposit date:2018-06-07
Release date:2019-06-19
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Identification of a natural ligand of the hazel allergen Cor a 1.
Sci Rep, 9, 2019
8PSB
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Three-layered parallel G-quadruplex with snapback loop from a G-rich sequence with five G-runs
Descriptor: DNA (5'-D(*AP*GP*GP*GP*TP*AP*GP*GP*GP*CP*GP*GP*CP*GP*GP*GP*GP*AP*CP*GP*GP*GP*T)-3')
Authors:Vianney, Y.M, Schroeder, N, Jana, J, Chojetzki, G, Weisz, K.
Deposit date:2023-07-13
Release date:2023-09-27
Last modified:2023-10-25
Method:SOLUTION NMR
Cite:Showcasing Different G-Quadruplex Folds of a G-Rich Sequence: Between Rule-Based Prediction and Butterfly Effect.
J.Am.Chem.Soc., 145, 2023
8R4E
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Hybrid-1R G-quadruplex with a +(lpp) loop progression
Descriptor: DNA (27-MER)
Authors:Jana, J, Vianney, Y.M, Weisz, K.
Deposit date:2023-11-13
Release date:2023-12-27
Last modified:2024-01-31
Method:SOLUTION NMR
Cite:Impact of loop length and duplex extensions on the design of hybrid-type G-quadruplexes.
Chem.Commun.(Camb.), 60, 2024
8R4W
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(3+1) hybrid-2 G-quadruplex with a -(llp) loop progression
Descriptor: DNA (25-MER)
Authors:Jana, J, Vianney, Y.M, Weisz, K.
Deposit date:2023-11-14
Release date:2023-12-27
Last modified:2024-01-31
Method:SOLUTION NMR
Cite:Impact of loop length and duplex extensions on the design of hybrid-type G-quadruplexes.
Chem.Commun.(Camb.), 60, 2024
8QKX
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Solution structure of a bimolecular quadruplex-duplex hybrid containing a V-shaped loop
Descriptor: DNA (5'-D(*CP*TP*CP*CP*AP*GP*CP*TP*GP*GP*GP*TP*GP*AP*GP*GP*GP*GP*CP*TP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*GP*GP*AP*GP*CP*TP*GP*GP*AP*GP*TP*T)-3')
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2023-09-18
Release date:2024-02-07
Method:SOLUTION NMR
Cite:Structural Aspects of Split G-Quadruplexes in Quadruplex-Duplex Hybrid Systems
Chemistryselect, 2024
1E10
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[2Fe-2S]-Ferredoxin from Halobacterium salinarum
Descriptor: ACETYL GROUP, FE2/S2 (INORGANIC) CLUSTER, FERREDOXIN
Authors:Marg, B.-L, Schweimer, K, Oesterhelt, D, Roesch, P, Sticht, H.
Deposit date:2000-04-12
Release date:2001-04-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A Two-Alpha-Helix Extra Domain Mediates the Halophilic Character of a Plant-Type Ferredoxin from Halophilic Archaea.
Biochemistry, 44, 2005
4GQB
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Crystal Structure of the human PRMT5:MEP50 Complex
Descriptor: (2S,5S,6E)-2,5-diamino-6-[(3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxydihydrofuran-2(3H)-ylidene]hexanoic acid, Histone H4 peptide, Methylosome protein 50, ...
Authors:Antonysamy, S, Bonday, Z, Campbell, R, Doyle, B, Druzina, Z, Gheyi, T, Han, B, Jungheim, L.N, Qian, Y, Rauch, C, Russell, M, Sauder, J.M, Wasserman, S.R, Weichert, K, Willard, F.S, Zhang, A, Emtage, S.
Deposit date:2012-08-22
Release date:2012-10-17
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal structure of the human PRMT5:MEP50 complex.
Proc.Natl.Acad.Sci.USA, 109, 2012
8ABD
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Solution structure of Phen-DC3 intercalating into a quadruplex-duplex hybrid
Descriptor: DNA (36-MER), N2,N9-bis(1-methylquinolin-3-yl)-1,10-phenanthroline-2,9-dicarboxamide
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2022-07-04
Release date:2022-11-02
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:High-affinity binding at quadruplex-duplex junctions: rather the rule than the exception.
Nucleic Acids Res., 50, 2022
8ABN
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Solution structure of a phenyl-indoloquinoline intercalating into a quadruplex-duplex hybrid
Descriptor: DNA (27-MER), diethyl-[3-[[4-(4,5,9-trimethyl-10H-indolo[3,2-b]quinolin-5-ium-11-yl)phenyl]carbonylamino]propyl]azanium
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2022-07-04
Release date:2022-11-16
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:High-affinity binding at quadruplex-duplex junctions: rather the rule than the exception.
Nucleic Acids Res., 50, 2022
1WCN
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NMR structure of the carboxyterminal domains of Escherichia coli NusA
Descriptor: TRANSCRIPTION ELONGATION PROTEIN NUSA
Authors:Eisenmann, A, Schwarz, S, Schweimer, K, Roesch, P.
Deposit date:2004-11-18
Release date:2005-08-31
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The E. Coli Nusa Carboxy-Terminal Domains are Structurally Similar and Show Specific Rnap- and Lambdan Interactions
Protein Sci., 14, 2005
1WCL
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NMR structure of the carboxyterminal domains of Escherichia coli NusA
Descriptor: TRANSCRIPTION ELONGATION PROTEIN NUSA
Authors:Eisenmann, A, Schwarz, S, Schweimer, K, Roesch, P.
Deposit date:2004-11-17
Release date:2005-08-31
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The E. Coli Nusa Carboxy-Terminal Domains are Structurally Similar and Show Specific Rnap- and Lambdan Interactions
Protein Sci., 14, 2005
1W1F
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SH3 DOMAIN OF HUMAN LYN TYROSINE KINASE
Descriptor: TYROSINE-PROTEIN KINASE LYN
Authors:Bauer, F, Schweimer, K, Hoffmann, S, Roesch, P, Sticht, H.
Deposit date:2004-06-17
Release date:2005-07-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Characterization of Lyn-SH3 Domain in Complex with a Herpesviral Protein Reveals an Extended Recognition Motif that Enhances Binding Affinity.
Protein Sci., 14, 2005
1WA7
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SH3 DOMAIN OF HUMAN LYN TYROSINE KINASE IN COMPLEX WITH A HERPESVIRAL LIGAND
Descriptor: HYPOTHETICAL 28.7 KDA PROTEIN IN DHFR 3'REGION (ORF1), TYROSINE-PROTEIN KINASE LYN
Authors:Bauer, F, Schweimer, K, Hoffmann, S, Roesch, P, Sticht, H.
Deposit date:2004-10-25
Release date:2005-07-07
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Investigation of the Binding of a Herpesviral Protein to the SH3 Domain of Tyrosine Kinase Lck.
Biochemistry, 41, 2002
8V8Z
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Lipoprotein(a) Kringle IV domain 8 - Lp(a) KIV8 in complex with LY3473329
Descriptor: Apolipoprotein(a), muvalaplin
Authors:Hendle, J, Weichert, K, Sauder, J.M.
Deposit date:2023-12-06
Release date:2024-05-08
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Discovery of potent small-molecule inhibitors of lipoprotein(a) formation.
Nature, 629, 2024

225158

數據於2024-09-18公開中

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