Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 120 results

8R6G
DownloadVisualize
BU of 8r6g by Molmil
A quadruplex-duplex hybrid with a three-layered chair G-quadruplex topology
Descriptor: DNA (33-MER)
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2023-11-22
Release date:2024-03-13
Last modified:2024-03-27
Method:SOLUTION NMR
Cite:Structural Differences at Quadruplex-Duplex Interfaces Enable Ligand-Induced Topological Transitions.
Adv Sci, 2024
6RS3
DownloadVisualize
BU of 6rs3 by Molmil
2'-F-riboguanosine modified G-quadruplex with V-loop
Descriptor: F1415
Authors:Haase, L, Weisz, K.
Deposit date:2019-05-21
Release date:2019-11-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Sugar Puckering Drives G-Quadruplex Refolding: Implications for V-Shaped Loops.
Chemistry, 26, 2020
6ERL
DownloadVisualize
BU of 6erl by Molmil
Quadruplex with flipped tetrad formed by the c-myc promoter sequence
Descriptor: cmbr-481317
Authors:Karg, B, Weisz, K.
Deposit date:2017-10-18
Release date:2018-06-13
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Loop Length Affects Syn-Anti Conformational Rearrangements in Parallel G-Quadruplexes.
Chemistry, 2018
6EQY
DownloadVisualize
BU of 6eqy by Molmil
4th KOW domain of human hSpt5
Descriptor: Transcription elongation factor SPT5
Authors:Zuber, P.K, Schweimer, K, Roesch, P, Woehrl, B.M.
Deposit date:2017-10-16
Release date:2018-10-17
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure and nucleic acid binding properties of KOW domains 4 and 6-7 of human transcription elongation factor DSIF.
Sci Rep, 8, 2018
6GQ9
DownloadVisualize
BU of 6gq9 by Molmil
Solution structure of the hazel allergen Cor a 1.0401
Descriptor: Major allergen Cor a 1.0401
Authors:Jacob, T.P, Schweimer, K, Seutter von Loetzen, C, Woehrl, B.M.
Deposit date:2018-06-07
Release date:2019-06-19
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Identification of a natural ligand of the hazel allergen Cor a 1.
Sci Rep, 9, 2019
6ER0
DownloadVisualize
BU of 6er0 by Molmil
6th KOW domain of human hSpt5
Descriptor: Transcription elongation factor SPT5
Authors:Hahn, L, Schweimer, K, Roesch, P, Woehrl, B.M.
Deposit date:2017-10-16
Release date:2018-10-31
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure and nucleic acid binding properties of KOW domains 4 and 6-7 of human transcription elongation factor DSIF.
Sci Rep, 8, 2018
6F4Z
DownloadVisualize
BU of 6f4z by Molmil
2'F-araG modified quadruplex with flipped G-tract and central tetrad
Descriptor: DNA (5'-D(*GP*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*GP*(GFL)P*GP*GP*AP*CP*GP*GP*G)-3')
Authors:Dickerhoff, J, Weisz, K.
Deposit date:2017-11-30
Release date:2018-04-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Fluorine-Mediated Editing of a G-Quadruplex Folding Pathway.
Chembiochem, 19, 2018
6FFR
DownloadVisualize
BU of 6ffr by Molmil
DNA-RNA Hybrid Quadruplex with Flipped Tetrad
Descriptor: DNA/RNA (5'-R(*G)-D(P*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*GP*GP*GP*GP*AP*C)-R(P*G)-D(P*GP*G)-3')
Authors:Haase, L, Dickerhoff, J, Weisz, K.
Deposit date:2018-01-09
Release date:2018-09-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:DNA-RNA Hybrid Quadruplexes Reveal Interactions that Favor RNA Parallel Topologies.
Chemistry, 24, 2018
4LCT
DownloadVisualize
BU of 4lct by Molmil
Crystal Structure and Versatile Functional Roles of the COP9 Signalosome Subunit 1
Descriptor: COP9 signalosome complex subunit 1, SULFATE ION
Authors:Lee, J.-H, Yi, L, Li, J, Schweitzer, K, Borgmann, M, Naumann, M, Wu, H.
Deposit date:2013-06-23
Release date:2013-07-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure and versatile functional roles of the COP9 signalosome subunit 1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GQB
DownloadVisualize
BU of 4gqb by Molmil
Crystal Structure of the human PRMT5:MEP50 Complex
Descriptor: (2S,5S,6E)-2,5-diamino-6-[(3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxydihydrofuran-2(3H)-ylidene]hexanoic acid, Histone H4 peptide, Methylosome protein 50, ...
Authors:Antonysamy, S, Bonday, Z, Campbell, R, Doyle, B, Druzina, Z, Gheyi, T, Han, B, Jungheim, L.N, Qian, Y, Rauch, C, Russell, M, Sauder, J.M, Wasserman, S.R, Weichert, K, Willard, F.S, Zhang, A, Emtage, S.
Deposit date:2012-08-22
Release date:2012-10-17
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal structure of the human PRMT5:MEP50 complex.
Proc.Natl.Acad.Sci.USA, 109, 2012
6BIT
DownloadVisualize
BU of 6bit by Molmil
SIRPalpha antibody complex
Descriptor: KWAR23 Fab heavy chain, KWAR23 Fab light chain, Tyrosine-protein phosphatase non-receptor type substrate 1
Authors:Ring, N.G, Herndler-Brandstetter, D, Weiskopf, K, Shan, L, Volkmer, J.P, George, B.M, Lietzenmayer, M, McKenna, K.M, Naik, T.J, McCarty, A, Zheng, Y, Ring, A.M, Flavell, R.A, Weissman, I.L.
Deposit date:2017-11-03
Release date:2017-12-06
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.191 Å)
Cite:Anti-SIRP alpha antibody immunotherapy enhances neutrophil and macrophage antitumor activity.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1WCN
DownloadVisualize
BU of 1wcn by Molmil
NMR structure of the carboxyterminal domains of Escherichia coli NusA
Descriptor: TRANSCRIPTION ELONGATION PROTEIN NUSA
Authors:Eisenmann, A, Schwarz, S, Schweimer, K, Roesch, P.
Deposit date:2004-11-18
Release date:2005-08-31
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The E. Coli Nusa Carboxy-Terminal Domains are Structurally Similar and Show Specific Rnap- and Lambdan Interactions
Protein Sci., 14, 2005
1WCL
DownloadVisualize
BU of 1wcl by Molmil
NMR structure of the carboxyterminal domains of Escherichia coli NusA
Descriptor: TRANSCRIPTION ELONGATION PROTEIN NUSA
Authors:Eisenmann, A, Schwarz, S, Schweimer, K, Roesch, P.
Deposit date:2004-11-17
Release date:2005-08-31
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The E. Coli Nusa Carboxy-Terminal Domains are Structurally Similar and Show Specific Rnap- and Lambdan Interactions
Protein Sci., 14, 2005
1WA7
DownloadVisualize
BU of 1wa7 by Molmil
SH3 DOMAIN OF HUMAN LYN TYROSINE KINASE IN COMPLEX WITH A HERPESVIRAL LIGAND
Descriptor: HYPOTHETICAL 28.7 KDA PROTEIN IN DHFR 3'REGION (ORF1), TYROSINE-PROTEIN KINASE LYN
Authors:Bauer, F, Schweimer, K, Hoffmann, S, Roesch, P, Sticht, H.
Deposit date:2004-10-25
Release date:2005-07-07
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Investigation of the Binding of a Herpesviral Protein to the SH3 Domain of Tyrosine Kinase Lck.
Biochemistry, 41, 2002
1W1F
DownloadVisualize
BU of 1w1f by Molmil
SH3 DOMAIN OF HUMAN LYN TYROSINE KINASE
Descriptor: TYROSINE-PROTEIN KINASE LYN
Authors:Bauer, F, Schweimer, K, Hoffmann, S, Roesch, P, Sticht, H.
Deposit date:2004-06-17
Release date:2005-07-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Characterization of Lyn-SH3 Domain in Complex with a Herpesviral Protein Reveals an Extended Recognition Motif that Enhances Binding Affinity.
Protein Sci., 14, 2005
6C2R
DownloadVisualize
BU of 6c2r by Molmil
Aurora A ligand complex
Descriptor: (2R,4R)-1-[(3-chloro-2-fluorophenyl)methyl]-4-({3-fluoro-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyridin-2-yl}methyl)-2-methylpiperidine-4-carboxylic acid, Aurora kinase A, SULFATE ION
Authors:Antonysamy, S, Pustilnik, A, Manglicmot, D, Froning, K, Weichert, K, Wasserman, S.
Deposit date:2018-01-08
Release date:2019-01-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of theRB1Tumor Suppressor Gene.
Cancer Discov, 9, 2019
6C2T
DownloadVisualize
BU of 6c2t by Molmil
Aurora A ligand complex
Descriptor: (2S,4R)-1-[(3-chloro-2-fluorophenyl)methyl]-2-methyl-4-({3-[(1,3-thiazol-2-yl)amino]isoquinolin-1-yl}methyl)piperidine-4-carboxylic acid, Aurora kinase A, DIMETHYL SULFOXIDE, ...
Authors:Antonysamy, S, Pustilnik, A, Manglicmot, D, Froning, K, Weichert, K, Wasserman, S.
Deposit date:2018-01-08
Release date:2019-01-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of theRB1Tumor Suppressor Gene.
Cancer Discov, 9, 2019
5KN5
DownloadVisualize
BU of 5kn5 by Molmil
TGFalpha/Epiregulin complex with neutralizing antibody LY3016859
Descriptor: Epiregulin Antibody LY3016859 Fab Heavy Chain, Epiregulin Antibody LY3016859 Fab Light Chain, Protransforming growth factor alpha, ...
Authors:Atwell, S, Boyles, J.S, Clawson, D.K, Druzina, Z, Josef, G.H, Weichert, K, Witcher, D.R.
Deposit date:2016-06-27
Release date:2016-08-31
Last modified:2016-11-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of selectivity and neutralizing activity of a TGF alpha /epiregulin specific antibody.
Protein Sci., 25, 2016
5KSC
DownloadVisualize
BU of 5ksc by Molmil
E166A/R274N/R276N Toho-1 Beta-lactamase aztreonam acyl-enzyme intermediate
Descriptor: 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-oxo-2-{[(2S,3S)-1-oxo-3-(sulfoamino)butan-2-yl]amino}ethylidene]amino}oxy)-2-methylpropanoic acid, Beta-lactamase Toho-1
Authors:Vandavasi, V.G, Langan, P.S, Weiss, K, Parks, J.M, Cooper, J.B, Ginell, S.L, Coates, L.
Deposit date:2016-07-08
Release date:2016-11-09
Last modified:2019-12-04
Method:NEUTRON DIFFRACTION (2.1 Å)
Cite:Active-Site Protonation States in an Acyl-Enzyme Intermediate of a Class A beta-Lactamase with a Monobactam Substrate.
Antimicrob. Agents Chemother., 61, 2017
2KTT
DownloadVisualize
BU of 2ktt by Molmil
Solution Structure of a Covalently Bound Pyrrolo[2,1-c][1,4]benzodiazepine-Benzimidazole Hybrid to a 10mer DNA Duplex
Descriptor: (11aS)-7-methoxy-8-(3-{4-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]phenoxy}propoxy)-1,2,3,10,11,11a-hexahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one, 5'-D(*AP*AP*CP*AP*AP*TP*TP*GP*TP*T)-3'
Authors:Rettig, M, Weingarth, M, Langel, W, Kamal, A, Kumar, P.P, Weisz, K.
Deposit date:2010-02-08
Release date:2010-03-09
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of a covalently bound pyrrolo[2,1-c][1,4]benzodiazepine-benzimidazole hybrid to a 10mer DNA duplex.
Biochemistry, 48, 2009
8A8V
DownloadVisualize
BU of 8a8v by Molmil
Mycobacterium tuberculosis ClpC1 hexamer structure bound to the natural product antibiotic Cyclomarin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide
Authors:Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K.
Deposit date:2022-06-24
Release date:2022-10-26
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action.
J.Biol.Chem., 298, 2022
8A8W
DownloadVisualize
BU of 8a8w by Molmil
Mycobacterium tuberculosis ClpC1 hexamer structure bound to the natural product antibiotic Ecumycin (class 1)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide
Authors:Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K.
Deposit date:2022-06-24
Release date:2022-10-26
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (4.29 Å)
Cite:Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action.
J.Biol.Chem., 298, 2022
8A8U
DownloadVisualize
BU of 8a8u by Molmil
Mycobacterium tuberculosis ClpC1 hexamer structure
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide
Authors:Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K.
Deposit date:2022-06-24
Release date:2022-10-26
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action.
J.Biol.Chem., 298, 2022
2HCC
DownloadVisualize
BU of 2hcc by Molmil
SOLUTION STRUCTURE OF THE HUMAN CHEMOKINE HCC-2, NMR, 30 STRUCTURES
Descriptor: HUMAN CHEMOKINE HCC-2
Authors:Sticht, H, Escher, S.E, Schweimer, K, Forssmann, W.G, Roesch, P, Adermann, K.
Deposit date:1998-07-03
Release date:1999-07-13
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the human CC chemokine 2: A monomeric representative of the CC chemokine subtype.
Biochemistry, 38, 1999
2UZ5
DownloadVisualize
BU of 2uz5 by Molmil
Solution structure of the fkbp-domain of Legionella pneumophila Mip
Descriptor: MACROPHAGE INFECTIVITY POTENTIATOR
Authors:Ceymann, A, Horstmann, M, Ehses, P, Schweimer, K, Steinert, M, Kamphausen, T, Fischer, G, Hacker, J, Rosch, P, Faber, C.
Deposit date:2007-04-25
Release date:2007-06-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Domain Motions of the Mip Protein from Legionella Pneumophila
Biochemistry, 45, 2006

221716

数据于2024-06-26公开中

PDB statisticsPDBj update infoContact PDBjnumon