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PDB: 410 results

3M9J
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Crystal structure of human thioredoxin C69/73S double mutant, reduced form
Descriptor: Thioredoxin
Authors:Weichsel, A, Montfort, W.R.
Deposit date:2010-03-22
Release date:2010-08-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal structure of human thioredoxin revealing an unraveled helix and exposed S-nitrosation site.
Protein Sci., 19, 2010
3M9K
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Crystal structure of human thioredoxin C69/73S double-mutant, oxidized form
Descriptor: (4S,5S)-1,2-DITHIANE-4,5-DIOL, SULFATE ION, Thioredoxin
Authors:Weichsel, A, Montfort, W.R.
Deposit date:2010-03-22
Release date:2010-08-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of human thioredoxin revealing an unraveled helix and exposed S-nitrosation site.
Protein Sci., 19, 2010
3IHM
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Structure of the oxygenase component of a Pseudomonas styrene monooxygenase
Descriptor: Styrene monooxygenase A
Authors:Rosenzweig, A.C, Ukaegbu, U.E, Gassner, G.
Deposit date:2009-07-30
Release date:2010-04-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and ligand binding properties of the epoxidase component of styrene monooxygenase
Biochemistry, 49, 2010
8AC0
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RNA polymerase at U-rich pause bound to regulatory RNA putL - active, closed clamp state
Descriptor: DNA Non-template strand, DNA Template strand, DNA-directed RNA polymerase subunit alpha, ...
Authors:Weixlbaumer, A, Dey, S.
Deposit date:2022-07-05
Release date:2022-10-19
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insights into RNA-mediated transcription regulation in bacteria.
Mol.Cell, 82, 2022
3BBC
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Crystal structure of R88A mutant of the NM23-H2 transcription factor
Descriptor: Nucleoside diphosphate kinase B
Authors:Weichsel, A, Montfort, W.R.
Deposit date:2007-11-09
Release date:2008-09-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:NM23-H2 may play an indirect role in transcriptional activation of c-myc gene expression but does not cleave the nuclease hypersensitive element III1.
Mol.Cancer Ther., 8, 2009
2UUB
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Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUU-codon in the A-site and paromomycin.
Descriptor: 16S Ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Weixlbaumer, A, Murphy, F.V, Dziergowska, A, Malkiewicz, A, Vendeix, F.A.P, Agris, P.F, Ramakrishnan, V.
Deposit date:2007-03-01
Release date:2007-05-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism for Expanding the Decoding Capacity of Transfer Rnas by Modification of Uridines
Nat.Struct.Mol.Biol., 14, 2007
2UUA
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Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUC-codon in the A-site and paromomycin.
Descriptor: 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Weixlbaumer, A, Murphy, F.V, Dziergowska, A, Malkiewicz, A, Vendeix, F.A.P, Agris, P.F, Ramakrishnan, V.
Deposit date:2007-03-01
Release date:2007-05-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines.
Nat. Struct. Mol. Biol., 14, 2007
2UU9
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Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUG-codon in the A-site and paromomycin.
Descriptor: 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Weixlbaumer, A, Murphy, F.V, Dziergowska, A, Malkiewicz, A, Vendeix, F.A.P, Agris, P.F, Ramakrishnan, V.
Deposit date:2007-03-01
Release date:2007-05-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines.
Nat. Struct. Mol. Biol., 14, 2007
2UUC
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Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUA-codon in the A-site and paromomycin.
Descriptor: 16S Ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Weixlbaumer, A, Murphy, F.V, Dziergowska, A, Malkiewicz, A, Vendeix, F.A.P, Agris, P.F, Ramakrishnan, V.
Deposit date:2007-03-01
Release date:2007-05-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines.
Nat. Struct. Mol. Biol., 14, 2007
3E2U
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Crystal structure of the zink-knuckle 2 domain of human CLIP-170 in complex with CAP-Gly domain of human dynactin-1 (p150-GLUED)
Descriptor: CAP-Gly domain-containing linker protein 1, Dynactin subunit 1, ZINC ION
Authors:Weisbrich, A, Honnappa, S, Capitani, G, Steinmetz, M.O.
Deposit date:2008-08-06
Release date:2008-08-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure-function relationship of CAP-Gly domains
Nat.Struct.Mol.Biol., 14, 2007
3BBB
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Crystal structure of the NM23-H2 transcription factor complex with dinucleotide d(AG)
Descriptor: DNA (5'-D(*AP*G)-3'), Nucleoside diphosphate kinase B
Authors:Weichsel, A, Montfort, W.R.
Deposit date:2007-11-09
Release date:2008-09-23
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:NM23-H2 may play an indirect role in transcriptional activation of c-myc gene expression but does not cleave the nuclease hypersensitive element III1.
Mol.Cancer Ther., 8, 2009
3NP1
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CRYSTAL STRUCTURE OF THE COMPLEX OF NITROPHORIN 1 FROM RHODNIUS PROLIXUS WITH CYANIDE
Descriptor: CYANIDE ION, NITROPHORIN 1, PHOSPHATE ION, ...
Authors:Weichsel, A, Andersen, J.F, Champagne, D.E, Walker, F.A, Montfort, W.R.
Deposit date:1998-01-22
Release date:1998-05-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of a nitric oxide transport protein from a blood-sucking insect.
Nat.Struct.Biol., 5, 1998
2GTF
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Crystal structure of nitrophorin 2 complex with pyrimidine
Descriptor: Nitrophorin-2, PROTOPORPHYRIN IX CONTAINING FE, PYRIMIDINE
Authors:Weichsel, A, Montfort, W.R.
Deposit date:2006-04-27
Release date:2007-03-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structures, ligand induced conformational change and heme deformation in complexes of nitrophorin 2, a nitric oxide transport protein from rhodnius prolixus
To be Published
2EU7
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Crystal structure of D1A mutant of nitrophorin 2 complexed with ammonia
Descriptor: AMMONIA, Nitrophorin 2, PROTOPORPHYRIN IX CONTAINING FE
Authors:Weichsel, A, Montfort, W.R.
Deposit date:2005-10-28
Release date:2006-10-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal structures, ligand induced conformational change and heme deformation in complexes of nitrophorin 2, a nitric oxide transport protein from rhodnius prolixus
To be Published
2HYS
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BU of 2hys by Molmil
Crystal structure of nitrophorin 2 complexed with cyanide
Descriptor: CYANIDE ION, Nitrophorin-2, PROTOPORPHYRIN IX CONTAINING FE
Authors:Weichsel, A, Montfort, W.R.
Deposit date:2006-08-07
Release date:2006-10-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Assignment of the Ferriheme Resonances of the Low-Spin Complexes of Nitrophorins 1 and 4 by (1)H and (13)C NMR Spectroscopy: Comparison to Structural Data Obtained from X-ray Crystallography.
Inorg.Chem., 46, 2007
2IMQ
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Crystal structure of ferrous cimex nitrophorin
Descriptor: PROTOPORPHYRIN IX CONTAINING FE, Salivary nitrophorin
Authors:Weichsel, A, Montfort, W.R.
Deposit date:2006-10-04
Release date:2007-08-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystallographic and spectroscopic characterization of ferrous complexes of cimex nitrophorin, a heme-thiolate protein from the bedbug
To be Published
2NP1
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CRYSTAL STRUCTURE OF NITROPHORIN 1 FROM RHODNIUS PROLIXUS
Descriptor: AMMONIUM ION, DIHYDROGENPHOSPHATE ION, NITROPHORIN 1, ...
Authors:Weichsel, A, Montfort, W.R.
Deposit date:1998-01-19
Release date:1998-05-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of a nitric oxide transport protein from a blood-sucking insect.
Nat.Struct.Biol., 5, 1998
2HSH
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BU of 2hsh by Molmil
Crystal structure of C73S mutant of human thioredoxin-1 oxidized with H2O2
Descriptor: PHOSPHATE ION, Thioredoxin
Authors:Weichsel, A, Montfort, W.R.
Deposit date:2006-07-21
Release date:2006-12-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Buried s-nitrosocysteine revealed in crystal structures of human thioredoxin.
Biochemistry, 46, 2007
2HXK
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Crystal structure of S-nitroso thioredoxin
Descriptor: ETHANOL, Thioredoxin
Authors:Weichsel, A, Montfort, W.R.
Deposit date:2006-08-03
Release date:2006-12-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Buried s-nitrosocysteine revealed in crystal structures of human thioredoxin.
Biochemistry, 46, 2007
6GCH
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BU of 6gch by Molmil
STRUCTURE OF CHYMOTRYPSIN-*TRIFLUOROMETHYL KETONE INHIBITOR COMPLEXES. COMPARISON OF SLOWLY AND RAPIDLY EQUILIBRATING INHIBITORS
Descriptor: 1,1,1-TRIFLUORO-3-ACETAMIDO-4-PHENYL BUTAN-2-ONE(N-ACETYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE), GAMMA-CHYMOTRYPSIN A
Authors:Brady, K, Wei, A, Ringe, D, Abeles, R.H.
Deposit date:1990-04-06
Release date:1990-10-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of chymotrypsin-trifluoromethyl ketone inhibitor complexes: comparison of slowly and rapidly equilibrating inhibitors.
Biochemistry, 29, 1990
1PPG
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The refined 2.3 angstroms crystal structure of human leukocyte elastase in a complex with a valine chloromethyl ketone inhibitor
Descriptor: HUMAN LEUKOCYTE ELASTASE, MEO-SUCCINYL-ALA-ALA-PRO-VAL CHLOROMETHYLKETONE, alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Bode, W, Wei, A-Z.
Deposit date:1991-10-24
Release date:1994-01-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The refined 2.3 A crystal structure of human leukocyte elastase in a complex with a valine chloromethyl ketone inhibitor.
FEBS Lett., 234, 1988
1PPF
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X-RAY CRYSTAL STRUCTURE OF THE COMPLEX OF HUMAN LEUKOCYTE ELASTASE (PMN ELASTASE) AND THE THIRD DOMAIN OF THE TURKEY OVOMUCOID INHIBITOR
Descriptor: HUMAN LEUKOCYTE ELASTASE, TURKEY OVOMUCOID INHIBITOR (OMTKY3), alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Bode, W, Wei, A-Z.
Deposit date:1991-10-24
Release date:1994-01-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystal structure of the complex of human leukocyte elastase (PMN elastase) and the third domain of the turkey ovomucoid inhibitor.
EMBO J., 5, 1986
7YL2
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Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor Y07004
Descriptor: Bromodomain-containing protein 4, GLYCEROL, N-(1-ethyl-2-oxidanylidene-3H-indol-5-yl)cyclohexanesulfonamide, ...
Authors:Huang, Y, Wei, A, Dong, R, Xu, H, Zhang, C, Chen, Z, Li, J, Wu, X, Zhang, Y, Xu, Y.
Deposit date:2022-07-25
Release date:2023-07-26
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor Y07004
To Be Published
4V51
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Structure of the Thermus thermophilus 70S ribosome complexed with mRNA, tRNA and paromomycin
Descriptor: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Selmer, M, Dunham, C.M, Murphy, F.V, Weixlbaumer, A, Petry, S, Weir, J.R, Kelley, A.C, Ramakrishnan, V.
Deposit date:2006-07-31
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the 70S ribosome complexed with mRNA and tRNA.
Science, 313, 2006
4V5D
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Structure of the Thermus thermophilus 70S ribosome in complex with mRNA, paromomycin, acylated A- and P-site tRNAs, and E-site tRNA.
Descriptor: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Voorhees, R.M, Weixlbaumer, A, Loakes, D, Kelley, A.C, Ramakrishnan, V.
Deposit date:2009-03-24
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome.
Nat. Struct. Mol. Biol., 16, 2009

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