1PYO
Crystal Structure of Human Caspase-2 in Complex with Acetyl-Leu-Asp-Glu-Ser-Asp-cho
Summary for 1PYO
Entry DOI | 10.2210/pdb1pyo/pdb |
Related PRD ID | PRD_000241 |
Descriptor | Caspase-2, ACETYL-LEU-ASP-GLU-SER-ASJ, ... (4 entities in total) |
Functional Keywords | apoptosis, caspase, alpha-beta, thiol protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Mitochondrion outer membrane; Multi-pass membrane protein (By similarity): P36114 |
Total number of polymer chains | 6 |
Total formula weight | 62601.63 |
Authors | Schweizer, A.,Briand, C.,Grutter, M.G. (deposition date: 2003-07-09, release date: 2003-08-26, Last modification date: 2023-11-15) |
Primary citation | Schweizer, A.,Briand, C.,Grutter, M.G. Crystal structure of caspase-2, apical initiator of the intrinsic apoptotic pathway. J.Biol.Chem., 278:42441-42447, 2003 Cited by PubMed: 12920126DOI: 10.1074/jbc.M304895200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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