Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
| C | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| C | 0008234 | molecular_function | cysteine-type peptidase activity |
| D | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
| D | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR CHAIN E OF RESIDUES 401 TO 406 |
| Chain | Residue |
| B | ASN232 |
| B | THR233 |
| B | TYR273 |
| E | LEU402 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR CHAIN F OF RESIDUES 401 TO 406 |
| Chain | Residue |
| B | ASP269 |
| D | ASN232 |
| D | THR233 |
| D | LYS234 |
| F | LEU402 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR CHAIN E OF ACETYL-LEU-ASP-GLU-SER-ASJ |
| Chain | Residue |
| A | ARG54 |
| A | HIS112 |
| A | GLY113 |
| A | GLN153 |
| A | CYS155 |
| B | ALA228 |
| B | ALA229 |
| B | MET230 |
| B | ARG231 |
| B | ASN232 |
| B | THR233 |
| B | TRP238 |
| B | GLY272 |
| B | TYR273 |
| B | ALA274 |
| B | PHE279 |
| B | HOH345 |
| E | HOH383 |
| site_id | AC4 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR CHAIN F OF ACETYL-LEU-ASP-GLU-SER-ASJ |
| Chain | Residue |
| C | GLN24 |
| C | ARG54 |
| C | HIS112 |
| C | GLY113 |
| C | GLN153 |
| C | CYS155 |
| C | HOH240 |
| D | ALA229 |
| D | MET230 |
| D | ARG231 |
| D | ASN232 |
| D | THR233 |
| D | TRP238 |
| D | GLY272 |
| D | TYR273 |
| D | PHE279 |
| D | ARG294 |
| F | HOH167 |
| F | HOH220 |
| F | HOH252 |
| F | HOH266 |
Functional Information from PROSITE/UniProt
| site_id | PS01121 |
| Number of Residues | 15 |
| Details | CASPASE_HIS Caspase family histidine active site. HrvtdSciVaLLSHG |
| Chain | Residue | Details |
| A | HIS99-GLY113 | |
| site_id | PS01122 |
| Number of Residues | 12 |
| Details | CASPASE_CYS Caspase family cysteine active site. KPKMFFIQACRG |
| Chain | Residue | Details |
| A | LYS146-GLY157 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Propeptide: {"featureId":"PRO_0000004543"} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1qx3 |
| Chain | Residue | Details |
| A | CYS155 | |
| A | GLY113 | |
| A | HIS112 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1qx3 |
| Chain | Residue | Details |
| C | CYS155 | |
| C | GLY113 | |
| C | HIS112 | |
