4J8R
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![BU of 4j8r by Molmil](/molmil-images/mine/4j8r) | Structure of an octapeptide repeat of the prion protein bound to the POM2 Fab antibody fragment | Descriptor: | Heavy chain of POM2 Fab, Light chain of POM2 Fab, Major prion protein | Authors: | Swayampakula, M, Baral, P.K, Kav, N.N.V, Aguzzi, A, James, M.N.G. | Deposit date: | 2013-02-14 | Release date: | 2013-05-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.303 Å) | Cite: | The crystal structure of an octapeptide repeat of the Prion protein in complex with a Fab fragment of the POM2 antibody. Protein Sci., 22, 2013
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8R5I
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![BU of 8r5i by Molmil](/molmil-images/mine/8r5i) | In situ structure of the Vaccinia virus (WR) A4/A10 palisade trimer in mature virions by flexible fitting into a cryoET map | Descriptor: | Core protein A10, Core protein A4 | Authors: | Calcraft, T, Hernandez-Gonzalez, M, Nans, A, Rosenthal, P.B, Way, M. | Deposit date: | 2023-11-16 | Release date: | 2024-01-10 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (9.7 Å) | Cite: | Palisade structure in intact vaccinia virions. Mbio, 15, 2024
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8ARH
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![BU of 8arh by Molmil](/molmil-images/mine/8arh) | In situ subtomogram average of Vaccinia virus (WR) D13 lattice, on immature virions | Descriptor: | Scaffold protein D13 | Authors: | Calcraft, T, Hernandez-Gonzalez, M, Nans, A, Rosenthal, P.B, Way, M. | Deposit date: | 2022-08-16 | Release date: | 2023-02-01 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (19.200001 Å) | Cite: | A succession of two viral lattices drives vaccinia virus assembly. Plos Biol., 21, 2023
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6EJN
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![BU of 6ejn by Molmil](/molmil-images/mine/6ejn) | |
3J82
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![BU of 3j82 by Molmil](/molmil-images/mine/3j82) | Electron cryo-microscopy of DNGR-1 in complex with F-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | Authors: | Hanc, P, Fujii, T, Yamada, Y, Huotari, J, Schulz, O, Ahrens, S, Kjaer, S, Way, M, Namba, K, Reis e Sousa, C. | Deposit date: | 2014-09-25 | Release date: | 2015-05-20 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (7.7 Å) | Cite: | Structure of the Complex of F-Actin and DNGR-1, a C-Type Lectin Receptor Involved in Dendritic Cell Cross-Presentation of Dead Cell-Associated Antigens. Immunity, 42, 2015
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6WX1
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![BU of 6wx1 by Molmil](/molmil-images/mine/6wx1) | Antigen Binding Fragment of OKT9 | Descriptor: | GLYCEROL, OKT9 Fab Heavy Chain, OKT9 Fab Light Chain | Authors: | Rodriguez, J.A, Helguera, G, Sawaya, M, Cascio, D, Collazo, M, Flores, M, Zink, S, Ferrero, S, Payes, C, Fuentes, D, Short, C. | Deposit date: | 2020-05-09 | Release date: | 2021-05-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Antibody-Based Inhibition of Pathogenic New World Hemorrhagic Fever Mammarenaviruses by Steric Occlusion of the Human Transferrin Receptor 1 Apical Domain. J.Virol., 95, 2021
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1PRQ
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![BU of 1prq by Molmil](/molmil-images/mine/1prq) | ACANTHAMOEBA CASTELLANII PROFILIN IA | Descriptor: | PROFILIN IA | Authors: | Fedorov, A.A, Pollard, T.D, Way, M, Lattman, E.E, Almo, S.C. | Deposit date: | 1997-08-18 | Release date: | 1997-12-24 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal packing induces a conformational change in profilin-I from Acanthamoeba castellanii. J.Struct.Biol., 123, 1998
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3LE4
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![BU of 3le4 by Molmil](/molmil-images/mine/3le4) | |
4YX2
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![BU of 4yx2 by Molmil](/molmil-images/mine/4yx2) | Crystal structure of Bovine prion protein complexed with POM1 FAB | Descriptor: | Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN | Authors: | Baral, P.K, Swayampakula, M, James, M.N.G. | Deposit date: | 2015-03-22 | Release date: | 2015-09-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.194 Å) | Cite: | X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins. J.Struct.Biol., 192, 2015
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4YXL
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![BU of 4yxl by Molmil](/molmil-images/mine/4yxl) | Crystal structure of Syrian hamster prion protein complexed with POM1 FAB | Descriptor: | Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN, ... | Authors: | Baral, P.K, Swayampakula, M, James, M.N.G. | Deposit date: | 2015-03-23 | Release date: | 2015-09-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.604 Å) | Cite: | X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins. J.Struct.Biol., 192, 2015
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4YXH
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![BU of 4yxh by Molmil](/molmil-images/mine/4yxh) | Crystal structure of Deer prion protein complexed with POM1 FAB | Descriptor: | Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN, ... | Authors: | Baral, P.K, Swayampakula, M, James, M.N.G. | Deposit date: | 2015-03-23 | Release date: | 2015-09-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins. J.Struct.Biol., 192, 2015
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4YXK
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![BU of 4yxk by Molmil](/molmil-images/mine/4yxk) | Crystal structure of Elk prion protein complexed with POM1 FAB | Descriptor: | Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN, ... | Authors: | Baral, P.K, Swayampakula, M, James, M.N.G. | Deposit date: | 2015-03-23 | Release date: | 2015-09-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.805 Å) | Cite: | X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins. J.Struct.Biol., 192, 2015
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6WLA
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![BU of 6wla by Molmil](/molmil-images/mine/6wla) | Antigen binding fragment of ch128.1 | Descriptor: | Fab ch128.1 heavy chain, Fab ch128.1 light chain, GLYCEROL | Authors: | Helguera, G, Rodriguez, J.A, Sawaya, M, Cascio, D, Zink, S, Ziegenbein, J, Short, C. | Deposit date: | 2020-04-18 | Release date: | 2021-03-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Host receptor-targeted therapeutic approach to counter pathogenic New World mammarenavirus infections. Nat Commun, 13, 2022
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4UNV
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![BU of 4unv by Molmil](/molmil-images/mine/4unv) | Covalent dimer of lambda variable domains | Descriptor: | IG LAMBDA CHAIN V-II REGION MGC, SULFATE ION | Authors: | Brumshtein, B, Esswein, S, Landau, M, Ryan, C, Whitelegge, J, Sawaya, M, Eisenberg, D.S. | Deposit date: | 2014-05-30 | Release date: | 2014-08-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Formation of Amyloid Fibers by Monomeric Light-Chain Variable Domains. J.Biol.Chem., 289, 2014
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7UCP
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![BU of 7ucp by Molmil](/molmil-images/mine/7ucp) | computationally designed macrocycle | Descriptor: | computationally designed cyclic peptide D8.3.p2 | Authors: | Bhardwaj, G, Baker, D, Rettie, S, Glynn, C, Sawaya, M. | Deposit date: | 2022-03-17 | Release date: | 2022-09-14 | Last modified: | 2022-09-28 | Method: | X-RAY DIFFRACTION (0.85 Å) | Cite: | Accurate de novo design of membrane-traversing macrocycles. Cell, 185, 2022
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4DGI
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![BU of 4dgi by Molmil](/molmil-images/mine/4dgi) | Structure of POM1 FAB fragment complexed with human PrPc Fragment 120-230 | Descriptor: | Major prion protein, POM1 Fab Heavy chain, POM1 Fab Light chain, ... | Authors: | Baral, P.K, Wieland, B, Swayampakula, M, James, M.N. | Deposit date: | 2012-01-26 | Release date: | 2012-10-31 | Last modified: | 2013-01-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural studies on the folded domain of the human prion protein bound to the Fab fragment of the antibody POM1. Acta Crystallogr.,Sect.D, 68, 2012
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2C0J
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![BU of 2c0j by Molmil](/molmil-images/mine/2c0j) | Crystal structure of the bet3-trs33 heterodimer | Descriptor: | PALMITIC ACID, R32611_2, TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3 | Authors: | Kim, M.-S, Yi, M.-J, Lee, K.-H, Wagner, J, Munger, C, Kim, Y.-G, Whiteway, M, Cygler, M, Oh, B.-H, Sacher, M. | Deposit date: | 2005-09-03 | Release date: | 2006-02-07 | Last modified: | 2015-01-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Biochemical and Crystallographic Studies Reveal a Specific Interaction between Trapp Subunits Trs33P and Bet3P Traffic, 6, 2005
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6AQ7
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![BU of 6aq7 by Molmil](/molmil-images/mine/6aq7) | Structure of POM6 FAB fragment complexed with mouse PrPc | Descriptor: | 3,3',3''-phosphanetriyltripropanoic acid, GLYCEROL, Major prion protein, ... | Authors: | Baral, P.K, Swayampakula, M, James, M.N.G. | Deposit date: | 2017-08-18 | Release date: | 2018-04-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structural characterization of POM6 Fab and mouse prion protein complex identifies key regions for prions conformational conversion. FEBS J., 285, 2018
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2A1H
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![BU of 2a1h by Molmil](/molmil-images/mine/2a1h) | X-ray crystal structure of human mitochondrial branched chain aminotransferase (BCATm) complexed with gabapentin | Descriptor: | ACETIC ACID, PYRIDOXAL-5'-PHOSPHATE, [1-(AMINOMETHYL)CYCLOHEXYL]ACETIC ACID, ... | Authors: | Goto, M, Miyahara, I, Hirotsu, K, Conway, M, Yennawar, N, Islam, M.M, Hutson, S.M. | Deposit date: | 2005-06-20 | Release date: | 2005-09-06 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin. J.Biol.Chem., 280, 2005
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4H88
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![BU of 4h88 by Molmil](/molmil-images/mine/4h88) | Structure of POM1 FAB fragment complexed with mouse PrPc Fragment 120-230 | Descriptor: | Major prion protein, POM1 FAB CHAIN H, POM1 FAB CHAIN L, ... | Authors: | Baral, P.K, Wieland, B, Swayampakula, M, James, M.N. | Deposit date: | 2012-09-21 | Release date: | 2013-07-31 | Last modified: | 2013-09-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein. Nature, 501, 2013
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4XFO
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![BU of 4xfo by Molmil](/molmil-images/mine/4xfo) | |
4XFN
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![BU of 4xfn by Molmil](/molmil-images/mine/4xfn) | |
4TNF
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![BU of 4tnf by Molmil](/molmil-images/mine/4tnf) | |
4TLU
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![BU of 4tlu by Molmil](/molmil-images/mine/4tlu) | |
4TNG
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![BU of 4tng by Molmil](/molmil-images/mine/4tng) | |