3SGM
| Bromoderivative-2 of amyloid-related segment of alphaB-crystallin residues 90-100 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-crystallin B chain | Authors: | Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D. | Deposit date: | 2011-06-15 | Release date: | 2012-03-21 | Method: | X-RAY DIFFRACTION (1.7006 Å) | Cite: | Atomic view of a toxic amyloid small oligomer. Science, 335, 2012
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3SEW
| Zn-mediated Polymer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form I) | Descriptor: | CHLORIDE ION, GLYCEROL, Maltose-binding periplasmic protein, ... | Authors: | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | Deposit date: | 2011-06-11 | Release date: | 2011-09-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
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1ZYT
| Crystal structure of spin labeled T4 Lysozyme (A82R1) | Descriptor: | 2-HYDROXYETHYL DISULFIDE, AZIDE ION, CHLORIDE ION, ... | Authors: | Fleissner, M.R, Cascio, D, Sawaya, M.R, Hideg, K, Hubbell, W.L. | Deposit date: | 2005-06-10 | Release date: | 2006-08-15 | Last modified: | 2023-10-25 | Method: | EPR (1.7 Å), X-RAY DIFFRACTION | Cite: | Structural origin of weakly ordered nitroxide motion in spin-labeled proteins Protein Sci., 18, 2009
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3SEY
| Zn-mediated Polymer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form II) | Descriptor: | ACETATE ION, GLYCEROL, Maltose-binding periplasmic protein, ... | Authors: | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | Deposit date: | 2011-06-11 | Release date: | 2011-09-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
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3SGN
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2A1H
| X-ray crystal structure of human mitochondrial branched chain aminotransferase (BCATm) complexed with gabapentin | Descriptor: | ACETIC ACID, PYRIDOXAL-5'-PHOSPHATE, [1-(AMINOMETHYL)CYCLOHEXYL]ACETIC ACID, ... | Authors: | Goto, M, Miyahara, I, Hirotsu, K, Conway, M, Yennawar, N, Islam, M.M, Hutson, S.M. | Deposit date: | 2005-06-20 | Release date: | 2005-09-06 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin. J.Biol.Chem., 280, 2005
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3SEU
| Zn-mediated Polymer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form III) | Descriptor: | ACETATE ION, GLYCEROL, Maltose-binding periplasmic protein, ... | Authors: | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | Deposit date: | 2011-06-11 | Release date: | 2011-09-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
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3SGP
| Amyloid-related segment of alphaB-crystallin residues 90-100 mutant V91L | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-crystallin B chain | Authors: | Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D. | Deposit date: | 2011-06-15 | Release date: | 2012-03-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.4016 Å) | Cite: | Atomic view of a toxic amyloid small oligomer. Science, 335, 2012
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3SEX
| Ni-mediated Dimer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form II) | Descriptor: | IODIDE ION, Maltose-binding periplasmic protein, NICKEL (II) ION, ... | Authors: | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | Deposit date: | 2011-06-11 | Release date: | 2011-09-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
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2BPF
| STRUCTURES OF TERNARY COMPLEXES OF RAT DNA POLYMERASE BETA, A DNA TEMPLATE-PRIMER, AND DDCTP | Descriptor: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*GP*GP*CP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*CP*GP*CP*CP*G)-3'), ... | Authors: | Pelletier, H, Sawaya, M.R, Kumar, A, Wilson, S.H, Kraut, J. | Deposit date: | 1994-05-19 | Release date: | 1994-12-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP. Science, 264, 1994
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6AVB
| CryoEM structure of Mical Oxidized Actin (Class 1) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle | Authors: | Grintsevich, E.E, Ge, P, Sawaya, M.R, Yesilyurt, H.G, Terman, J.R, Zhou, Z.H, Reisler, E. | Deposit date: | 2017-09-01 | Release date: | 2018-01-17 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Catastrophic disassembly of actin filaments via Mical-mediated oxidation. Nat Commun, 8, 2017
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4IQ4
| Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains, triple mutant, P21212 form | Descriptor: | Non-haem bromoperoxidase BPO-A2, Matrix protein 1 | Authors: | Lai, Y.-T, Sawaya, M.R, Yeates, T.O. | Deposit date: | 2013-01-10 | Release date: | 2013-07-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.495 Å) | Cite: | Structure and flexibility of nanoscale protein cages designed by symmetric self-assembly. J.Am.Chem.Soc., 135, 2013
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6AV9
| CryoEM structure of Mical Oxidized Actin (Class 1) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle | Authors: | Grintsevich, E.E, Ge, P, Sawaya, M.R, Yesilyurt, H.G, Terman, J.R, Zhou, Z.H, Reisler, E. | Deposit date: | 2017-09-01 | Release date: | 2018-01-17 | Last modified: | 2019-11-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Catastrophic disassembly of actin filaments via Mical-mediated oxidation. Nat Commun, 8, 2017
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4ITV
| Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains, triple mutant, P212121 form | Descriptor: | Non-haem bromoperoxidase BPO-A2, Matrix protein 1 | Authors: | Lai, Y.-T, Sawaya, M.R, Yeates, T.O. | Deposit date: | 2013-01-18 | Release date: | 2013-07-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.598 Å) | Cite: | Structure and flexibility of nanoscale protein cages designed by symmetric self-assembly. J.Am.Chem.Soc., 135, 2013
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3Q26
| Cyrstal structure of human alpha-synuclein (10-42) fused to maltose binding protein (MBP) | Descriptor: | GLYCEROL, Maltose-binding periplasmic protein/alpha-synuclein chimeric protein, SULFATE ION, ... | Authors: | Zhao, M, Sawaya, M.R, Cascio, D, Eisenberg, D. | Deposit date: | 2010-12-19 | Release date: | 2011-06-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Structures of segments of alpha-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation Protein Sci., 20, 2011
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3Q27
| Cyrstal structure of human alpha-synuclein (32-57) fused to maltose binding protein (MBP) | Descriptor: | GLYCEROL, Maltose-binding periplasmic protein/alpha-synuclein chimeric protein, SULFATE ION, ... | Authors: | Zhao, M, Sawaya, M.R, Cascio, D, Eisenberg, D. | Deposit date: | 2010-12-19 | Release date: | 2011-06-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.302 Å) | Cite: | Structures of segments of alpha-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation Protein Sci., 20, 2011
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3Q28
| Cyrstal structure of human alpha-synuclein (58-79) fused to maltose binding protein (MBP) | Descriptor: | Maltose-binding periplasmic protein/alpha-synuclein chimeric protein, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Zhao, M, Sawaya, M.R, Cascio, D, Eisenberg, D. | Deposit date: | 2010-12-19 | Release date: | 2011-06-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structures of segments of alpha-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation Protein Sci., 20, 2011
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3NVF
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3NVG
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2CUU
| Crystal structure of spin labeled T4 Lysozyme (V131R1) | Descriptor: | 2-HYDROXYETHYL DISULFIDE, AZIDE ION, CHLORIDE ION, ... | Authors: | Fleissner, M.R, Cascio, D, Sawaya, M.R, Hideg, K, Hubbell, W.L. | Deposit date: | 2005-05-28 | Release date: | 2006-08-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural origin of weakly ordered nitroxide motion in spin-labeled proteins Protein Sci., 18, 2009
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2G13
| CsoS1A with sulfate ion | Descriptor: | Major carboxysome shell protein 1A, SULFATE ION | Authors: | Tsai, Y, Sawaya, M.R, Cannon, G.C, Williams, E.B, Kerfeld, C.A, Yeates, T.O. | Deposit date: | 2006-02-13 | Release date: | 2007-02-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Structural Analysis of CsoS1A and the Protein Shell of the Halothiobacillus neapolitanus Carboxysome. Plos Biol., 5, 2007
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4IVJ
| Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains, triple mutant, I222 form | Descriptor: | Non-haem bromoperoxidase BPO-A2, Matrix protein 1 | Authors: | Lai, Y.-T, Sawaya, M.R, Yeates, T.O. | Deposit date: | 2013-01-23 | Release date: | 2013-07-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (7.351 Å) | Cite: | Structure and flexibility of nanoscale protein cages designed by symmetric self-assembly. J.Am.Chem.Soc., 135, 2013
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3Q9I
| LVFFA segment from Alzheimer's Amyloid-Beta displayed on 42-membered macrocycle scaffold, bromide derivative | Descriptor: | CHLORIDE ION, Cyclic pseudo-peptide LV(4BF)FA(ORN)(HAO)LK(ORN), GLYCEROL, ... | Authors: | Liu, C, Sawaya, M.R, Eisenberg, D, Nowick, J.S, Cheng, P, Zheng, J. | Deposit date: | 2011-01-07 | Release date: | 2011-06-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic beta-Sheet Mimics. J.Am.Chem.Soc., 133, 2011
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4LF2
| Hexameric Form II RuBisCO from Rhodopseudomonas palustris, activated and complexed with sulfate and magnesium | Descriptor: | CARBONATE ION, MAGNESIUM ION, Ribulose bisphosphate carboxylase, ... | Authors: | Chan, S, Satagopan, S, Sawaya, M.R, Eisenberg, D, Tabita, F.R, Perry, L.J. | Deposit date: | 2013-06-26 | Release date: | 2014-06-25 | Last modified: | 2016-07-20 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Structure-function studies with the unique hexameric form II ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) from Rhodopseudomonas palustris. J.Biol.Chem., 289, 2014
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3SB7
| Cu-mediated Trimer of T4 Lysozyme D61H/K65H/R76H/R80H by Synthetic Symmetrization | Descriptor: | COPPER (II) ION, GLYCEROL, Lysozyme | Authors: | Soriaga, A.B, Laganowsky, A, Zhao, M, Sawaya, M.R, Cascio, D, Yeates, T.O. | Deposit date: | 2011-06-03 | Release date: | 2011-09-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
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