3SGM
Bromoderivative-2 of amyloid-related segment of alphaB-crystallin residues 90-100
Summary for 3SGM
Entry DOI | 10.2210/pdb3sgm/pdb |
Related | 3SGN 3SGO 3SGP 3SGR 3SGS |
Descriptor | Alpha-crystallin B chain, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total) |
Functional Keywords | amyloid, amyloid oligomer, beta cylindrin, protein fibril |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P02511 |
Total number of polymer chains | 4 |
Total formula weight | 5227.57 |
Authors | Laganowsky, A.,Sawaya, M.R.,Cascio, D.,Eisenberg, D. (deposition date: 2011-06-15, release date: 2012-03-21) |
Primary citation | Laganowsky, A.,Liu, C.,Sawaya, M.R.,Whitelegge, J.P.,Park, J.,Zhao, M.,Pensalfini, A.,Soriaga, A.B.,Landau, M.,Teng, P.K.,Cascio, D.,Glabe, C.,Eisenberg, D. Atomic view of a toxic amyloid small oligomer. Science, 335:1228-1231, 2012 Cited by PubMed: 22403391DOI: 10.1126/science.1213151 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7006 Å) |
Structure validation
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