3SGR
Tandem repeat of amyloid-related segment of alphaB-crystallin residues 90-100 mutant V91L
Summary for 3SGR
Entry DOI | 10.2210/pdb3sgr/pdb |
Related | 3SGM 3SGN 3SGO 3SGP 3SGS |
Descriptor | Tandem repeat of amyloid-related segment of alphaB-crystallin residues 90-100 mutant V91L, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total) |
Functional Keywords | amyloid, amyloid oligomer, beta cylindrin, protein fibril |
Biological source | Homo sapiens More |
Cellular location | Cytoplasm : P02511 |
Total number of polymer chains | 6 |
Total formula weight | 15729.12 |
Authors | Laganowsky, A.,Sawaya, M.R.,Cascio, D.,Eisenberg, D. (deposition date: 2011-06-15, release date: 2012-03-21, Last modification date: 2024-02-28) |
Primary citation | Laganowsky, A.,Liu, C.,Sawaya, M.R.,Whitelegge, J.P.,Park, J.,Zhao, M.,Pensalfini, A.,Soriaga, A.B.,Landau, M.,Teng, P.K.,Cascio, D.,Glabe, C.,Eisenberg, D. Atomic view of a toxic amyloid small oligomer. Science, 335:1228-1231, 2012 Cited by PubMed: 22403391DOI: 10.1126/science.1213151 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.17 Å) |
Structure validation
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