3SGM

Bromoderivative-2 of amyloid-related segment of alphaB-crystallin residues 90-100

Summary for 3SGM

Entry DOI	10.2210/pdb3sgm/pdb
Related	3SGN 3SGO 3SGP 3SGR 3SGS
Descriptor	Alpha-crystallin B chain, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total)
Functional Keywords	amyloid, amyloid oligomer, beta cylindrin, protein fibril
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P02511
Total number of polymer chains	4
Total formula weight	5227.57
Authors	Laganowsky, A.,Sawaya, M.R.,Cascio, D.,Eisenberg, D. (deposition date: 2011-06-15, release date: 2012-03-21)
Primary citation	Laganowsky, A.,Liu, C.,Sawaya, M.R.,Whitelegge, J.P.,Park, J.,Zhao, M.,Pensalfini, A.,Soriaga, A.B.,Landau, M.,Teng, P.K.,Cascio, D.,Glabe, C.,Eisenberg, D. Atomic view of a toxic amyloid small oligomer. Science, 335:1228-1231, 2012 Cited by PubMed: 22403391 DOI: 10.1126/science.1213151 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7006 Å)

Structure validation