8HVR
 
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8ITR
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8ITT
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8JKE
 | | AfsR(T337A) transcription activation complex | | 分子名称: | DNA(65-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Wang, Y, Zheng, J. | | 登録日 | 2023-06-01 | | 公開日 | 2024-02-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | | 主引用文献 | Structural and functional characterization of AfsR, an SARP family transcriptional activator of antibiotic biosynthesis in Streptomyces.
Plos Biol., 22, 2024
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6L2W
 | | Crystal structure of a novel fold protein Gp72 from the freshwater cyanophage Mic1 | | 分子名称: | freshwater cyanophage protein | | 著者 | Wang, Y, Jin, H, Yang, F, Jiang, Y.L, Zhao, Y.Y, Chen, Z.P, Li, W.F, Chen, Y, Zhou, C.Z, Li, Q. | | 登録日 | 2019-10-07 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Crystal structure of a novel fold protein Gp72 from the freshwater cyanophage Mic1.
Proteins, 88, 2020
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7E4Z
 | | Crystal structure of tubulin in complex with Maytansinol | | 分子名称: | (1R,2S,3S,5S,6S,16E,18E,20R,21S)-11-chloro-6,21-dihydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18-pentaene-8,23-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Wang, Y, Li, W. | | 登録日 | 2021-02-16 | | 公開日 | 2021-07-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | C3 ester side chain plays a pivotal role in the antitumor activity of Maytansinoids.
Biochem.Biophys.Res.Commun., 566, 2021
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7E4Q
 | | Crystal structure of tubulin in complex with L-DM1-SMe | | 分子名称: | (1S,2R,3R,5R,6R,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18-pentaen-6-yl (2S)-2-{methyl[3-(methyldisulfanyl)propanoyl]amino}propanoate (non-preferred name), 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Wang, Y, Li, W. | | 登録日 | 2021-02-14 | | 公開日 | 2021-07-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | | 主引用文献 | C3 ester side chain plays a pivotal role in the antitumor activity of Maytansinoids.
Biochem.Biophys.Res.Commun., 566, 2021
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7E4R
 | | Crystal structure of tubulin in complex with D-DM1-SMe | | 分子名称: | (10E,12E)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl N-methyl-N-(3-(methylsulfinothioyl)propanoyl)-D-alaninate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Wang, Y, Li, W. | | 登録日 | 2021-02-15 | | 公開日 | 2021-07-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.597 Å) | | 主引用文献 | C3 ester side chain plays a pivotal role in the antitumor activity of Maytansinoids.
Biochem.Biophys.Res.Commun., 566, 2021
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8K1P
 | | mycobacterial efflux pump, ADP+vanadate bound state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CARDIOLIPIN, ... | | 著者 | Wang, Y, Wu, F, Zhang, L, Rao, Z. | | 登録日 | 2023-07-11 | | 公開日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | mycobacterial efflux pump, ADP+vanadate bound state
To Be Published
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8K1O
 | | mycobacterial efflux pump, AMPPNP bound state | | 分子名称: | CARDIOLIPIN, MAGNESIUM ION, Multidrug efflux system ATP-binding protein Rv1218c, ... | | 著者 | Wang, Y, Wu, F, Zhang, L, Rao, Z. | | 登録日 | 2023-07-11 | | 公開日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | mycobacterial efflux pump, AMPPNP bound state
To Be Published
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8K1N
 | | mycobacterial efflux pump, substrate-bound state | | 分子名称: | CARDIOLIPIN, Multidrug efflux system ATP-binding protein Rv1218c, Multidrug efflux system permease protein Rv1217c, ... | | 著者 | Wang, Y, Wu, F, Zhang, L, Rao, Z. | | 登録日 | 2023-07-11 | | 公開日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | mycobacterial efflux pump, substrate-bound state
To Be Published
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8K1M
 | | mycobacterial efflux pump, apo state | | 分子名称: | (1S)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CARDIOLIPIN, Multidrug efflux system ATP-binding protein Rv1218c, ... | | 著者 | Wang, Y, Wu, F, Zhang, L, Rao, Z. | | 登録日 | 2023-07-11 | | 公開日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | mycobacterial efflux pump, apo state
To Be Published
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7EN3
 | | Crystal structure of tubulin in complex with Tubulysin analogue TGL | | 分子名称: | (2S,4R)-5-(4-fluorophenyl)-2-methyl-4-[[2-[(1R,3R)-4-methyl-3-[5-methylhexyl-[(2S,3S)-3-methyl-2-[[(2R)-1-methylpiperidin-2-yl]carbonylamino]pentanoyl]amino]-1-oxidanyl-pentyl]-1,3-thiazol-4-yl]carbonylamino]pentanoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Wang, Y, Li, W. | | 登録日 | 2021-04-15 | | 公開日 | 2022-04-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.643 Å) | | 主引用文献 | The X-ray structure of tubulysin analogue TGL in complex with tubulin and three possible routes for the development of next-generation tubulysin analogues.
Biochem.Biophys.Res.Commun., 565, 2021
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7XEI
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7XEG
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7W5E
 | | Oxidase ChaP D49L mutant | | 分子名称: | ChaP, FE (III) ION | | 著者 | Wang, Y, Zheng, W, Meng, Z, Jin, Y, Zhu, J, Tan, R. | | 登録日 | 2021-11-30 | | 公開日 | 2022-10-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Alteration of the Catalytic Reaction Trajectory of a Vicinal Oxygen Chelate Enzyme by Directed Evolution.
Angew.Chem.Int.Ed.Engl., 61, 2022
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6ISO
 | | Human SIRT3 Recognizing H3K4cr | | 分子名称: | (2E)-BUT-2-ENAL, ARG-THR-LYS-GLN-THR-ALA-ARG, GLYCEROL, ... | | 著者 | Wang, Y, Hao, Q. | | 登録日 | 2018-11-17 | | 公開日 | 2019-01-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Identification of 'erasers' for lysine crotonylated histone marks using a chemical proteomics approach.
Elife, 3, 2014
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6JPS
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7CPO
 | | Crystal Structure of Anolis carolinensis MHC I complex | | 分子名称: | HIS-VAL-TYR-GLY-PRO-LEU-LYS-PRO-ILE, MHC CLASS I ANTIGEN, beta2-microglobulin | | 著者 | Wang, Y, Qu, Z, Ma, L, Wei, X, Zhang, N, Xia, C. | | 登録日 | 2020-08-07 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The Crystal Structure of the MHC Class I (MHC-I) Molecule in the Green Anole Lizard Demonstrates the Unique MHC-I System in Reptiles.
J Immunol., 206, 2021
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6LYH
 | | Crystal structure of tea N9-methyltransferase CkTcS in complex with SAH and 1,3,7-trimethyluric acid | | 分子名称: | 1,3,7-trimethyl-9H-purine-2,6,8-trione, N-methyltransferase CkTcS, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Wang, Y, Zhang, Z.-M. | | 登録日 | 2020-02-14 | | 公開日 | 2020-03-04 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.15000319 Å) | | 主引用文献 | Identification and characterization of N9-methyltransferase involved in converting caffeine into non-stimulatory theacrine in tea.
Nat Commun, 11, 2020
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7EF1
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7EEZ
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7EF2
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7EF3
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7EF0
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