6JUI
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![BU of 6jui by Molmil](/molmil-images/mine/6jui) | The atypical Myb-like protein Cdc5 contains two distinct nucleic acid-binding surfaces | Descriptor: | Pre-mRNA-splicing factor CEF1 | Authors: | Wang, C, Li, G, Li, M, Yang, J, Liu, J. | Deposit date: | 2019-04-14 | Release date: | 2020-02-19 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.402 Å) | Cite: | Two distinct nucleic acid binding surfaces of Cdc5 regulate development. Biochem.J., 476, 2019
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2KCG
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![BU of 2kcg by Molmil](/molmil-images/mine/2kcg) | Solution structure of cycloviolacin O2 | Descriptor: | Cycloviolacin-O2 | Authors: | Wang, C.K. | Deposit date: | 2008-12-22 | Release date: | 2009-07-21 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Despite a conserved cystine knot motif, different cyclotides have different membrane binding modes. Biophys.J., 97, 2009
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7EZO
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![BU of 7ezo by Molmil](/molmil-images/mine/7ezo) | |
2KCH
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![BU of 2kch by Molmil](/molmil-images/mine/2kch) | Solution structure of micelle-bound kalata B2 | Descriptor: | Kalata-B2 | Authors: | Wang, C.K. | Deposit date: | 2008-12-21 | Release date: | 2009-07-21 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Despite a conserved cystine knot motif, different cyclotides have different membrane binding modes. Biophys.J., 97, 2009
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8K48
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![BU of 8k48 by Molmil](/molmil-images/mine/8k48) | LTD of arabidopsis thaliana | Descriptor: | Protein LHCP TRANSLOCATION DEFECT | Authors: | Wang, C, Xu, X.M. | Deposit date: | 2023-07-17 | Release date: | 2024-07-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of Arabidopsis thaliana LTD To Be Published
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3ZH9
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![BU of 3zh9 by Molmil](/molmil-images/mine/3zh9) | Bacillus subtilis DNA clamp loader delta protein (YqeN) | Descriptor: | DELTA, GLYCEROL, SULFATE ION | Authors: | Suwannachart, C, Sedelnikova, S, Soultanas, P, Oldham, N.J, Rafferty, J.B. | Deposit date: | 2012-12-20 | Release date: | 2013-04-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Insights Into the Structure and Assembly of the Bacillus Subtilis Clamp-Loader Complex and its Interaction with the Replicative Helicase. Nucleic Acids Res., 41, 2013
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7YCV
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![BU of 7ycv by Molmil](/molmil-images/mine/7ycv) | |
7YCW
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![BU of 7ycw by Molmil](/molmil-images/mine/7ycw) | |
7YCU
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![BU of 7ycu by Molmil](/molmil-images/mine/7ycu) | |
7YCS
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![BU of 7ycs by Molmil](/molmil-images/mine/7ycs) | |
5TF8
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![BU of 5tf8 by Molmil](/molmil-images/mine/5tf8) | Nucleotide-binding domain 1 of the human cystic fibrosis transmembrane conductance regulator (CFTR) with dTTP | Descriptor: | Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE | Authors: | Wang, C, Aleksandrov, A.A, Yang, Z, Forouhar, F, Proctor, E, Kota, P, An, J, Kaplan, A, Khazanov, N, Boel, G, Stockwell, B.R, Senderowitz, H, Dokholyan, N.V, Riordan, J.R, Brouillette, C.G, Hunt, J.F. | Deposit date: | 2016-09-24 | Release date: | 2018-05-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.861 Å) | Cite: | Thermodynamic correction of F508del-CFTR by ligand binding to a remote site in the mutated domain To Be Published
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5TFJ
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![BU of 5tfj by Molmil](/molmil-images/mine/5tfj) | Nucleotide-binding domain 1 of the human cystic fibrosis transmembrane conductance regulator (CFTR) with dCTP | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | Authors: | Wang, C, Aleksandrov, A.A, Yang, Z, Forouhar, F, Proctor, E, Kota, P, An, J, Kaplan, A, Khazanov, N, Boel, G, Stockwell, B.R, Senderowitz, H, Dokholyan, N.V, Riordan, J.R, Brouillette, C.G, Hunt, J.F. | Deposit date: | 2016-09-25 | Release date: | 2018-05-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Thermodynamic correction of F508del-CFTR by ligand binding to a remote site in the mutated domain To Be Published
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5TF7
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![BU of 5tf7 by Molmil](/molmil-images/mine/5tf7) | Nucleotide-binding domain 1 of the human cystic fibrosis transmembrane conductance regulator (CFTR) with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | Authors: | Wang, C, Aleksandrov, A.A, Yang, Z, Forouhar, F, Proctor, E, Kota, P, An, J, Kaplan, A, Khazanov, N, Boel, G, Stockwell, B.R, Senderowitz, H, Dokholyan, N.V, Riordan, J.R, Brouillette, C.G, Hunt, J.F. | Deposit date: | 2016-09-24 | Release date: | 2018-05-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.931 Å) | Cite: | Thermodynamic correction of F508del-CFTR by ligand binding to a remote site in the mutated domain To Be Published
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5TFF
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![BU of 5tff by Molmil](/molmil-images/mine/5tff) | Nucleotide-binding domain 1 of the human cystic fibrosis transmembrane conductance regulator (CFTR) with UTP | Descriptor: | Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, URIDINE 5'-TRIPHOSPHATE | Authors: | Wang, C, Aleksandrov, A.A, Yang, Z, Forouhar, F, Proctor, E, Kota, P, An, J, Kaplan, A, Khazanov, N, Boel, G, Stockwell, B.R, Senderowitz, H, Dokholyan, N.V, Riordan, J.R, Brouillette, C.G, Hunt, J.F. | Deposit date: | 2016-09-25 | Release date: | 2018-05-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.891 Å) | Cite: | Thermodynamic correction of F508del-CFTR by ligand binding to a remote site in the mutated domain To Be Published
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5TGK
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![BU of 5tgk by Molmil](/molmil-images/mine/5tgk) | Nucleotide-binding domain 1 of the human cystic fibrosis transmembrane conductance regulator (CFTR) with dATP | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | Authors: | Wang, C, Aleksandrov, A.A, Yang, Z, Forouhar, F, Proctor, E, Kota, P, An, J, Kaplan, A, Khazanov, N, Boel, G, Stockwell, B.R, Senderowitz, H, Dokholyan, N.V, Riordan, J.R, Brouillette, C.G, Hunt, J.F. | Deposit date: | 2016-09-28 | Release date: | 2018-05-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.912 Å) | Cite: | Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator. J. Biol. Chem., 2018
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2KHB
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2KVX
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![BU of 2kvx by Molmil](/molmil-images/mine/2kvx) | Solution structure of kalata B12 | Descriptor: | Kalata-B12 | Authors: | Wang, C.K. | Deposit date: | 2010-03-29 | Release date: | 2011-03-09 | Last modified: | 2016-06-01 | Method: | SOLUTION NMR | Cite: | The role of conserved Glu residue on cyclotide stability and activity: a structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant. Biochemistry, 50, 2011
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7XDG
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![BU of 7xdg by Molmil](/molmil-images/mine/7xdg) | Cryo-EM structures of human mitochondrial NAD(P)+-dependent malic enzyme in a ternary complex with NAD+ and allosteric inhibitor MDSA | Descriptor: | 5-[(3-carboxy-4-oxidanyl-phenyl)methyl]-2-oxidanyl-benzoic acid, NAD-dependent malic enzyme, mitochondrial, ... | Authors: | Wang, C.H, Hsieh, J.T, Ho, M.C, Hung, H.C. | Deposit date: | 2022-03-27 | Release date: | 2023-03-29 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Suppression of the human malic enzyme 2 modifies energy metabolism and inhibits cellular respiration Commun Biol, 6, 2023
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7XDF
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![BU of 7xdf by Molmil](/molmil-images/mine/7xdf) | Cryo-EM structures of human mitochondrial NAD(P)+-dependent malic enzyme in a ternary complex with NAD+ and allosteric inhibitor EA | Descriptor: | 4-[(3-carboxy-2-oxidanyl-naphthalen-1-yl)methyl]-3-oxidanyl-naphthalene-2-carboxylic acid, NAD-dependent malic enzyme, mitochondrial, ... | Authors: | Wang, C.H, Hsieh, J.T, Ho, M.C, Hung, H.C. | Deposit date: | 2022-03-27 | Release date: | 2023-03-29 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (2.72 Å) | Cite: | Suppression of the human malic enzyme 2 modifies energy metabolism and inhibits cellular respiration Commun Biol, 6, 2023
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7XDE
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![BU of 7xde by Molmil](/molmil-images/mine/7xde) | Cryo-EM structures of human mitochondrial NAD(P)+-dependent malic enzyme in apo form | Descriptor: | NAD-dependent malic enzyme, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Wang, C.H, Hsieh, J.T, Ho, M.C, Hung, H.C. | Deposit date: | 2022-03-26 | Release date: | 2023-03-29 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.72 Å) | Cite: | Suppression of the human malic enzyme 2 modifies energy metabolism and inhibits cellular respiration Commun Biol, 6, 2023
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2K7G
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![BU of 2k7g by Molmil](/molmil-images/mine/2k7g) | Solution Structure of varv F | Descriptor: | Varv peptide F | Authors: | Wang, C.K. | Deposit date: | 2008-08-10 | Release date: | 2009-02-10 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Combined X-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffold J.Biol.Chem., 284, 2009
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7YAN
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7ZEA
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7WN1
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![BU of 7wn1 by Molmil](/molmil-images/mine/7wn1) | Structure of PfNT1(Y190A) in complex with nanobody 48 and inosine | Descriptor: | Equilibrative nucleoside/nucleobase transporter, INOSINE, nanobody48 | Authors: | Wang, C, Deng, D, Ren, R.B, Yu, L.Y. | Deposit date: | 2022-01-17 | Release date: | 2023-02-01 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1. Nat Commun, 14, 2023
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7UVP
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![BU of 7uvp by Molmil](/molmil-images/mine/7uvp) | |