7LA4
 
 | | Integrin AlphaIIbBeta3-PT25-2 Complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Bush, M.W, Walz, T, Coller, B, Filizola, M, Spasic, A, Nesic, D, Li, J. | | Deposit date: | 2021-01-05 | | Release date: | 2022-01-12 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Electron microscopy shows that binding of monoclonal antibody PT25-2 primes integrin alpha IIb beta 3 for ligand binding.
Blood Adv, 5, 2021
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3J6J
 | | 3.6 Angstrom resolution MAVS filament generated from helical reconstruction | | Descriptor: | Mitochondrial antiviral-signaling protein | | Authors: | Wu, B, Peisley, A, Li, Z, Egelman, E, Walz, T, Penczek, P, Hur, S. | | Deposit date: | 2014-03-13 | | Release date: | 2014-07-30 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.64 Å) | | Cite: | Molecular Imprinting as a Signal-Activation Mechanism of the Viral RNA Sensor RIG-I.
Mol.Cell, 55, 2014
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8TW4
 | | TCR in nanodisc ND-I | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | Authors: | Notti, R.Q, Walz, T. | | Deposit date: | 2023-08-20 | | Release date: | 2024-10-02 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | The resting and ligand-bound states of the membrane-embedded human T-cell receptor-CD3 complex.
Biorxiv, 2024
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8TW6
 | | TCR in nanodisc ND-II | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, T cell receptor beta variable 6-5,T cell receptor beta chain MC.7.G5,MCHERRY, ... | | Authors: | Notti, R.Q, Walz, T. | | Deposit date: | 2023-08-20 | | Release date: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | The resting and ligand-bound states of the membrane-embedded human T-cell receptor-CD3 complex.
Biorxiv, 2024
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1FQY
 | | STRUCTURE OF AQUAPORIN-1 AT 3.8 A RESOLUTION BY ELECTRON CRYSTALLOGRAPHY | | Descriptor: | AQUAPORIN-1 | | Authors: | Murata, K, Mitsuoka, K, Hirai, T, Walz, T, Agre, P, Heymann, J.B, Engel, A, Fujiyoshi, Y. | | Deposit date: | 2000-09-07 | | Release date: | 2000-10-18 | | Last modified: | 2024-04-17 | | Method: | ELECTRON CRYSTALLOGRAPHY (3.8 Å) | | Cite: | Structural determinants of water permeation through aquaporin-1.
Nature, 407, 2000
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9C3E
 | | TCR - CD3 complex bound to HLA | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, Cancer/testis antigen 1,Beta-2-microglobulin,MHC class I antigen, ... | | Authors: | Notti, R.Q, Walz, T. | | Deposit date: | 2024-05-31 | | Release date: | 2024-10-02 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | The resting and ligand-bound states of the membrane-embedded human T-cell receptor-CD3 complex.
Biorxiv, 2024
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9BBC
 | | TCR GDN detergent micelle | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | Authors: | Notti, R.Q, Walz, T. | | Deposit date: | 2024-04-05 | | Release date: | 2024-10-02 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | The resting and ligand-bound states of the membrane-embedded human T-cell receptor-CD3 complex.
Biorxiv, 2024
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7U5C
 | | Cryo-EM structure of human CST bound to DNA polymerase alpha-primase in a recruitment state | | Descriptor: | CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... | | Authors: | Cai, S.W, Zinder, J.C, Svetlov, V, Bush, M.W, Nudler, E, Walz, T, de Lange, T. | | Deposit date: | 2022-03-02 | | Release date: | 2022-05-18 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Cryo-EM structure of the human CST-Pol alpha /primase complex in a recruitment state.
Nat.Struct.Mol.Biol., 29, 2022
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3IYV
 | | Clathrin D6 coat as full-length Triskelions | | Descriptor: | Clathrin heavy chain, Clathrin light chain A | | Authors: | Johnson, G.T, Fotin, A, Cheng, Y, Sliz, P, Grigorieff, N, Harrison, S.C, Kirchhausen, T, Walz, T. | | Deposit date: | 2010-06-17 | | Release date: | 2010-07-21 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (7.9 Å) | | Cite: | Molecular model for a complete clathrin lattice from electron cryomicroscopy.
Nature, 432, 2004
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1XI5
 | | Clathrin D6 coat with auxilin J-domain | | Descriptor: | Auxilin J-domain, Clathrin heavy chain | | Authors: | Fotin, A, Cheng, Y, Grigorieff, N, Walz, T, Harrison, S.C, Kirchhausen, T. | | Deposit date: | 2004-09-21 | | Release date: | 2004-11-02 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (12 Å) | | Cite: | Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating
Nature, 432, 2004
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1XI4
 | | Clathrin D6 Coat | | Descriptor: | Clathrin heavy chain, Clathrin light chain A | | Authors: | Fotin, A, Cheng, Y, Sliz, P, Grigorieff, N, Harrison, S.C, Kirchhausen, T, Walz, T. | | Deposit date: | 2004-09-21 | | Release date: | 2004-11-02 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (7.9 Å) | | Cite: | Molecular model for a complete clathrin lattice from electron cryomicroscopy
Nature, 432, 2004
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7SC5
 | | Cytoplasmic tail deleted HIV Env trimer in nanodisc | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | | Authors: | Yang, S, Walz, T. | | Deposit date: | 2021-09-27 | | Release date: | 2022-11-09 | | Last modified: | 2023-02-22 | | Method: | ELECTRON MICROSCOPY (3.88 Å) | | Cite: | Dynamic HIV-1 spike motion creates vulnerability for its membrane-bound tripod to antibody attack.
Nat Commun, 13, 2022
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7SD3
 | | Cytoplasmic tail deleted HIV-1 Env bound with three 4E10 Fabs | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4E10 Fab heavy chain, ... | | Authors: | Yang, S, Walz, T. | | Deposit date: | 2021-09-29 | | Release date: | 2022-11-09 | | Last modified: | 2023-02-22 | | Method: | ELECTRON MICROSCOPY (3.67 Å) | | Cite: | Dynamic HIV-1 spike motion creates vulnerability for its membrane-bound tripod to antibody attack.
Nat Commun, 13, 2022
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2OF5
 | | Oligomeric Death Domain complex | | Descriptor: | Death domain-containing protein CRADD, Leucine-rich repeat and death domain-containing protein | | Authors: | Park, H.H, Logette, E, Raunser, S, Cuenin, S, Walz, T, Tschopp, J, Wu, H. | | Deposit date: | 2007-01-02 | | Release date: | 2007-04-17 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Death domain assembly mechanism revealed by crystal structure of the oligomeric PIDDosome core complex.
Cell(Cambridge,Mass.), 128, 2007
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6ORB
 | | Full-length S. pombe Mdn1 in the presence of ATP and Rbin-1 | | Descriptor: | Midasin | | Authors: | Chen, Z, Suzuki, H, Wang, A.C, DiMaio, F, Walz, T, Kapoor, T.M. | | Deposit date: | 2019-04-29 | | Release date: | 2019-05-29 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (7.7 Å) | | Cite: | Structural Insights into Mdn1, an Essential AAA Protein Required for Ribosome Biogenesis.
Cell, 175, 2018
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6OR5
 | | Full-length S. pombe Mdn1 in the presence of AMPPNP (ring region) | | Descriptor: | Midasin, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Chen, Z, Suzuki, H, Wang, A.C, DiMaio, F, Walz, T, Kapoor, T.M. | | Deposit date: | 2019-04-29 | | Release date: | 2019-05-29 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structural Insights into Mdn1, an Essential AAA Protein Required for Ribosome Biogenesis.
Cell, 175, 2018
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6XAS
 | | CryoEM Structure of E. coli Rho-dependent Transcription Pre-termination Complex | | Descriptor: | DNA (29-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Hao, Z.T, Kim, H.K, Walz, T, Nudler, E. | | Deposit date: | 2020-06-04 | | Release date: | 2020-12-16 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Pre-termination Transcription Complex: Structure and Function.
Mol.Cell, 81, 2021
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8SJY
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8SJX
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6XAV
 | | CryoEM Structure of E. coli Rho-dependent Transcription Pre-termination Complex bound with NusG | | Descriptor: | DNA (29-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Hao, Z.T, Kim, H.K, Walz, T, Nudler, E. | | Deposit date: | 2020-06-04 | | Release date: | 2020-12-16 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (7.7 Å) | | Cite: | Pre-termination Transcription Complex: Structure and Function.
Mol.Cell, 81, 2021
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1SOR
 | | Aquaporin-0 membrane junctions reveal the structure of a closed water pore | | Descriptor: | Aquaporin-0 | | Authors: | Gonen, T, Sliz, P, Kistler, J, Cheng, Y, Walz, T. | | Deposit date: | 2004-03-15 | | Release date: | 2004-05-11 | | Last modified: | 2023-08-23 | | Method: | ELECTRON CRYSTALLOGRAPHY (3 Å) | | Cite: | Aquaporin-0 membrane junctions reveal the structure of a closed water pore
Nature, 429, 2004
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3M9I
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5TTP
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7JJO
 | | Structural Basis of the Activation of Heterotrimeric Gs-protein by Isoproterenol-bound Beta1-Adrenergic Receptor | | Descriptor: | Beta1-Adrenergic Receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Su, M, Zhu, L, Zhang, Y, Paknejad, N, Dey, R, Huang, J, Lee, M.Y, Williams, D, Jordan, K.D, Eng, E.T, Ernst, O.P, Meyerson, J.R, Hite, R.K, Walz, T, Liu, W, Huang, X.Y. | | Deposit date: | 2020-07-27 | | Release date: | 2020-09-02 | | Last modified: | 2020-10-14 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Structural Basis of the Activation of Heterotrimeric Gs-Protein by Isoproterenol-Bound beta 1 -Adrenergic Receptor.
Mol.Cell, 80, 2020
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5TV4
 | | 3D cryo-EM reconstruction of nucleotide-free MsbA in lipid nanodisc | | Descriptor: | 3-HYDROXY-TETRADECANOIC ACID, L-glycero-alpha-D-manno-heptopyranose-(1-7)-L-glycero-alpha-D-manno-heptopyranose-(1-3)-L-glycero-alpha-D-manno-heptopyranose-(1-5)-[3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)]3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-alpha-D-glucopyranose-(1-6)-2-amino-2-deoxy-alpha-D-glucopyranose, LAURIC ACID, ... | | Authors: | Mi, W, Walz, T, Liao, M. | | Deposit date: | 2016-11-08 | | Release date: | 2017-09-20 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structural basis of MsbA-mediated lipopolysaccharide transport.
Nature, 549, 2017
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