8SJY
Structure of lens aquaporin-0 array in sphingomyelin/cholesterol bilayer (1SM:2Chol)
Summary for 8SJY
| Entry DOI | 10.2210/pdb8sjy/pdb |
| Descriptor | Lens fiber major intrinsic protein, [(E,2S,3R)-2-(hexadecanoylamino)-3-oxidanyl-octadec-4-enyl] 2-(trimethylazaniumyl)ethyl phosphate, CHOLESTEROL, ... (4 entities in total) |
| Functional Keywords | aquaporin, lens, cholesterol, lipid raft, membrane protein |
| Biological source | Ovis aries (sheep) |
| Total number of polymer chains | 1 |
| Total formula weight | 33346.64 |
| Authors | Chiu, P.-L.,Walz, T. (deposition date: 2023-04-18, release date: 2024-04-24, Last modification date: 2024-09-25) |
| Primary citation | Chiu, P.L.,Orjuela, J.D.,de Groot, B.L.,Aponte Santamaria, C.,Walz, T. Structure and dynamics of cholesterol-mediated aquaporin-0 arrays and implications for lipid rafts. Elife, 12:-, 2024 Cited by PubMed: 39222068DOI: 10.7554/eLife.90851 PDB entries with the same primary citation |
| Experimental method | ELECTRON CRYSTALLOGRAPHY (2.35 Å) |
Structure validation
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