7X9S
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![BU of 7x9s by Molmil](/molmil-images/mine/7x9s) | Crystal structure of a complex between the antirepressor GmaR and the transcriptional repressor MogR | Descriptor: | GmaR, Motility gene repressor MogR | Authors: | Cho, S.Y, Na, H.W, Oh, H.B, Kwak, Y.M, Song, W.S, Park, S.C, Yoon, S.I. | Deposit date: | 2022-03-16 | Release date: | 2022-11-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | Structural basis of flagellar motility regulation by the MogR repressor and the GmaR antirepressor in Listeria monocytogenes. Nucleic Acids Res., 50, 2022
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5KNS
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![BU of 5kns by Molmil](/molmil-images/mine/5kns) | E coli hypoxanthine guanine phosphoribosyltransferase in complexed with 9-[(N-phosphonoethyl-N-phosphonoethoxyethyl)-2-aminoethyl]hypoxanthine | Descriptor: | (2-{[2-(6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl](2-{[(E)-2-phosphonoethenyl]oxy}ethyl)amino}ethyl)phosphonic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Hypoxanthine-guanine phosphoribosyltransferase, ... | Authors: | Eng, W.S, Keough, D.T, Hockova, D, Janeba, Z. | Deposit date: | 2016-06-28 | Release date: | 2017-07-19 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.792 Å) | Cite: | Crystal Structures of Acyclic Nucleoside Phosphonates in Complex with Escherichia coli Hypoxanthine Phosphoribosyltransferase Chemistryselect, 1, 2016
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1RJ5
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![BU of 1rj5 by Molmil](/molmil-images/mine/1rj5) | Crystal Structure of the Extracellular Domain of Murine Carbonic Anhydrase XIV | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, CHLORIDE ION, ... | Authors: | Whittington, D.A, Grubb, J.H, Waheed, A, Shah, G.N, Sly, W.S, Christianson, D.W. | Deposit date: | 2003-11-18 | Release date: | 2004-03-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Expression, assay, and structure of the extracellular domain of murine carbonic anhydrase XIV: implications for selective inhibition of membrane-associated isozymes. J.Biol.Chem., 279, 2004
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8GR2
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![BU of 8gr2 by Molmil](/molmil-images/mine/8gr2) | |
1NY3
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![BU of 1ny3 by Molmil](/molmil-images/mine/1ny3) | Crystal structure of ADP bound to MAP KAP kinase 2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAP kinase-activated protein kinase 2 | Authors: | Underwood, K.W, Parris, K.D, Federico, E, Mosyak, L, Shane, T, Taylor, M, Svenson, K, Liu, Y, Hsiao, C.L, Wolfrom, S, Maguire, M, Malakian, K, Telliez, J.B, Lin, L.L, Kriz, R.W, Seehra, J, Somers, W.S, Stahl, M.L. | Deposit date: | 2003-02-11 | Release date: | 2003-10-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme Structure, 11, 2003
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7XFP
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![BU of 7xfp by Molmil](/molmil-images/mine/7xfp) | |
5KNP
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![BU of 5knp by Molmil](/molmil-images/mine/5knp) | Crystal structure of Mycobacterium tuberculosis hypoxanthine guanine phosphoribosyltransferase in complex with [3S,4R]-(4-(Hypoxanthin-9-yl)pyrrolidin-3-yl)-oxymethanephosphonic acid | Descriptor: | Hypoxanthine-guanine phosphoribosyltransferase, MAGNESIUM ION, PYROPHOSPHATE 2-, ... | Authors: | Eng, W.S, Rejman, D, Keough, D.T, Guddat, L.W. | Deposit date: | 2016-06-28 | Release date: | 2017-09-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal structure of Mycobacterium tuberculosis hypoxanthine guanine phosphoribosyltransferase in complex with pyrrolidine nucleoside phosphonate To Be Published
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4DME
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![BU of 4dme by Molmil](/molmil-images/mine/4dme) | GCN4 leucine zipper domain in a trimeric oligomerization state | Descriptor: | GCN4-p1 leucine zipper domain, SULFATE ION | Authors: | Oshaben, K.M, Salari, R, Chong, L.T, Horne, W.S. | Deposit date: | 2012-02-07 | Release date: | 2012-11-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Native GCN4 Leucine-Zipper Domain Does Not Uniquely Specify a Dimeric Oligomerization State. Biochemistry, 51, 2012
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4NX9
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![BU of 4nx9 by Molmil](/molmil-images/mine/4nx9) | Crystal structure of Pseudomonas aeruginosa flagellin FliC | Descriptor: | Flagellin | Authors: | Song, W.S, Yoon, S.I. | Deposit date: | 2013-12-09 | Release date: | 2014-01-29 | Last modified: | 2014-03-05 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of FliC flagellin from Pseudomonas aeruginosa and its implication in TLR5 binding and formation of the flagellar filament Biochem.Biophys.Res.Commun., 444, 2014
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5KU6
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![BU of 5ku6 by Molmil](/molmil-images/mine/5ku6) | Crystal structure for the complex of human carbonic anhydrase IV and methazolamide | Descriptor: | ACETATE ION, Carbonic anhydrase 4, GLYCEROL, ... | Authors: | Chen, Z, Waheed, A, Di Cera, E, Sly, W.S. | Deposit date: | 2016-07-12 | Release date: | 2017-07-26 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV. Eur. Biophys. J., 47, 2018
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4NJ4
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![BU of 4nj4 by Molmil](/molmil-images/mine/4nj4) | Crystal Structure of Human ALKBH5 | Descriptor: | GLYCEROL, MANGANESE (II) ION, N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE, ... | Authors: | Aik, W.S, McDonough, M.A, Schofield, C.J. | Deposit date: | 2013-11-08 | Release date: | 2014-01-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Structure of human RNA N6-methyladenine demethylase ALKBH5 provides insights into its mechanisms of nucleic acid recognition and demethylation. Nucleic Acids Res., 42, 2014
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5N6T
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1MUH
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![BU of 1muh by Molmil](/molmil-images/mine/1muh) | CRYSTAL STRUCTURE OF TN5 TRANSPOSASE COMPLEXED WITH TRANSPOSON END DNA | Descriptor: | DNA NON-TRANSFERRED STRAND, DNA TRANSFERRED STRAND, MAGNESIUM ION, ... | Authors: | Thoden, J.B, Holden, H.M, Davies, D.R, Goryshin, I.Y, Reznikoff, W.S, Rayment, I. | Deposit date: | 2002-09-23 | Release date: | 2002-09-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Three-dimensional structure of the Tn5 synaptic complex transposition intermediate. Science, 289, 2000
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1MX4
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![BU of 1mx4 by Molmil](/molmil-images/mine/1mx4) | Structure of p18INK4c (F82Q) | Descriptor: | Cyclin-dependent kinase 6 inhibitor | Authors: | Marmorstein, R, Venkataramani, R.N, MacLachlan, T.K, Chai, X, El-Deiry, W.S. | Deposit date: | 2002-10-01 | Release date: | 2002-10-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity J.Biol.Chem., 277, 2002
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1MX2
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![BU of 1mx2 by Molmil](/molmil-images/mine/1mx2) | Structure of F71N mutant of p18INK4c | Descriptor: | Cyclin-dependent kinase 6 inhibitor | Authors: | Marmorstein, R, Venkataramani, R.N, MacLachlan, T.K, Chai, X, El-Deiery, W.S. | Deposit date: | 2002-10-01 | Release date: | 2002-10-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity J.Biol.Chem., 277, 2002
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1MX6
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![BU of 1mx6 by Molmil](/molmil-images/mine/1mx6) | Structure of p18INK4c (F92N) | Descriptor: | Cyclin-dependent kinase 6 inhibitor | Authors: | Marmorstein, R, Venkataramani, R.N, MacLachlan, T.K, Chai, X, El-Deiry, W.S. | Deposit date: | 2002-10-01 | Release date: | 2002-10-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity J.Biol.Chem., 277, 2002
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3G7A
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![BU of 3g7a by Molmil](/molmil-images/mine/3g7a) | HIV gp41 six-helix bundle composed of a chimeric alpha+alpha/beta-peptide analogue of the CHR domain in complex with an NHR domain alpha-peptide | Descriptor: | ACETYL GROUP, Chimeric alpha+alpha/beta-peptide analogue of the HIV gp41 CHR domain, Envelope glycoprotein gp160, ... | Authors: | Horne, W.S, Johnson, L.M, Gellman, S.H. | Deposit date: | 2009-02-09 | Release date: | 2009-10-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers Proc.Natl.Acad.Sci.USA, 106, 2009
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7V4G
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![BU of 7v4g by Molmil](/molmil-images/mine/7v4g) | Crystal structure of human ALKBH5 in complex with m6A-containing ssRNA | Descriptor: | GLYCEROL, MANGANESE (II) ION, RNA (5'-R(P*GP*GP*(6MZ)P*C)-3'), ... | Authors: | Kaur, S, McDonough, M.A, Schofield, C.J, Aik, W.S. | Deposit date: | 2021-08-13 | Release date: | 2022-03-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Mechanisms of substrate recognition and N6-methyladenosine demethylation revealed by crystal structures of ALKBH5-RNA complexes. Nucleic Acids Res., 50, 2022
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4POO
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![BU of 4poo by Molmil](/molmil-images/mine/4poo) | The crystal structure of Bacillus subtilis YtqB in complex with SAM | Descriptor: | Putative RNA methylase, S-ADENOSYLMETHIONINE | Authors: | Park, S.C, Song, W.S, Yoon, S.I. | Deposit date: | 2014-02-26 | Release date: | 2014-04-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural analysis of a putative SAM-dependent methyltransferase, YtqB, from Bacillus subtilis Biochem.Biophys.Res.Commun., 446, 2014
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4NJ0
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![BU of 4nj0 by Molmil](/molmil-images/mine/4nj0) | GCN4-p1 single Val9 to Ile mutant | Descriptor: | General control protein GCN4 | Authors: | Oshaben, K.M, Horne, W.S. | Deposit date: | 2013-11-08 | Release date: | 2014-08-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Tuning assembly size in Peptide-based supramolecular polymers by modulation of subunit association affinity. Biomacromolecules, 15, 2014
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4NJ1
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![BU of 4nj1 by Molmil](/molmil-images/mine/4nj1) | GCN4-p1 double Val9, 23 to Ile mutant | Descriptor: | General control protein GCN4 | Authors: | Oshaben, K.M, Horne, W.S. | Deposit date: | 2013-11-08 | Release date: | 2014-08-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Tuning assembly size in Peptide-based supramolecular polymers by modulation of subunit association affinity. Biomacromolecules, 15, 2014
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1TZZ
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![BU of 1tzz by Molmil](/molmil-images/mine/1tzz) | Crystal structure of the protein L1841, unknown member of enolase superfamily from Bradyrhizobium japonicum | Descriptor: | Hypothetical protein L1841, MAGNESIUM ION | Authors: | Fedorov, A.A, Fedorov, E.V, Yew, W.S, Gerlt, J.A, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2004-07-12 | Release date: | 2004-10-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Crystal structure of the protein L1841, unknown member of enolase superfamily from Bradyrhizobium japonicum To be Published
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5JNC
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![BU of 5jnc by Molmil](/molmil-images/mine/5jnc) | Crystal structure for the complex of human carbonic anhydrase IV and 4-aminomethylbenzene sulfonamide | Descriptor: | 4-(aminomethyl)benzene-1-sulfonamide, ACETATE ION, Carbonic anhydrase 4, ... | Authors: | Chen, Z, Waheed, A, Di Cera, E, Sly, W.S. | Deposit date: | 2016-04-29 | Release date: | 2017-05-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV. Eur. Biophys. J., 47, 2018
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8G0Y
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![BU of 8g0y by Molmil](/molmil-images/mine/8g0y) | |
1U9E
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![BU of 1u9e by Molmil](/molmil-images/mine/1u9e) | CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH WAY-397 | Descriptor: | 2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL, Estrogen receptor beta, STEROID RECEPTOR COACTIVATOR-1 | Authors: | Manas, E.S, Unwalla, R.J, Xu, Z.B, Malamas, M.S, Miller, C.P, Harris, H.A, Hsiao, C, Akopian, T, Hum, W.T, Malakian, K, Wolfrom, S, Bapat, A, Bhat, R.A, Stahl, M.L, Somers, W.S, Alvarez, J.C. | Deposit date: | 2004-08-09 | Release date: | 2005-03-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure-Based Design Of Estrogen Receptor-beta Selective Ligands J.Am.Chem.Soc., 126, 2004
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