1NY3

Crystal structure of ADP bound to MAP KAP kinase 2

Summary for 1NY3

Related1NXK
DescriptorMAP kinase-activated protein kinase 2, ADENOSINE-5'-DIPHOSPHATE (2 entities in total)
Functional Keywordsmap kap kinase 2, mk2, adp, kinase, ser/thr kinase, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total molecular weight46056.94
Authors
Primary citation
Underwood, K.W.,Parris, K.D.,Federico, E.,Mosyak, L.,Czerwinski, R.M.,Shane, T.,Taylor, M.,Svenson, K.,Liu, Y.,Hsiao, C.L.,Wolfrom, S.,Maguire, M.,Malakian, K.,Telliez, J.B.,Lin, L.L.,Kriz, R.W.,Seehra, J.,Somers, W.S.,Stahl, M.L.
Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme
Structure, 11:627-636, 2003
PubMed: 12791252 (PDB entries with the same primary citation)
DOI: 10.1016/S0969-2126(03)00092-3
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers283.0%9.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution