1NXK

Crystal structure of staurosporine bound to MAP KAP kinase 2

Summary for 1NXK

Entry DOI	10.2210/pdb1nxk/pdb
Descriptor	MAP kinase-activated protein kinase 2, STAUROSPORINE, SULFATE ION, ... (4 entities in total)
Functional Keywords	protein kinase, mk2, phosphorylation, staurosporine, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	186828.14
Authors	Underwood, K.W.,Parris, K.D.,Federico, E.,Mosyak, L.,Czerwinski, R.M.,Shane, T.,Taylor, M.,Svenson, K.,Liu, Y.,Hsiao, C.L.,Wolfrom, S.,Malakian, K.,Telliez, J.B.,Lin, L.L.,Kriz, R.W.,Seehra, J.,Somers, W.S.,Stahl, M.L. (deposition date: 2003-02-10, release date: 2003-10-14, Last modification date: 2011-07-13)
Primary citation	Underwood, K.W.,Parris, K.D.,Federico, E.,Mosyak, L.,Czerwinski, R.M.,Shane, T.,Taylor, M.,Svenson, K.,Liu, Y.,Hsiao, C.L.,Wolfrom, S.,Maguire, M.,Malakian, K.,Telliez, J.B.,Lin, L.L.,Kriz, R.W.,Seehra, J.,Somers, W.S.,Stahl, M.L. Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme Structure, 11:627-636, 2003 Cited by PubMed: 12791252 DOI: 10.1016/S0969-2126(03)00092-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation