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PDB: 12895 results

3KI8
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BU of 3ki8 by Molmil
Crystal structure of hyperthermophilic nitrilase
Descriptor: ACETIC ACID, Beta ureidopropionase (Beta-alanine synthase), MAGNESIUM ION
Authors:Raczynska, J, Vorgias, C, Antranikian, G, Rypniewski, W.
Deposit date:2009-10-31
Release date:2010-11-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystallographic analysis of a thermoactive nitrilase.
J.Struct.Biol., 173, 2010
5C3P
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BU of 5c3p by Molmil
Crystal structure of the full-length Neurospora crassa T7H in complex with alpha-KG
Descriptor: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, NICKEL (II) ION, ...
Authors:Li, W, Zhang, T, Ding, J.
Deposit date:2015-06-17
Release date:2015-10-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular basis for the substrate specificity and catalytic mechanism of thymine-7-hydroxylase in fungi
Nucleic Acids Res., 43, 2015
3G1N
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BU of 3g1n by Molmil
Catalytic domain of the human E3 ubiquitin-protein ligase HUWE1
Descriptor: E3 ubiquitin-protein ligase HUWE1, SODIUM ION
Authors:Walker, J.R, Qiu, L, Li, Y, Davis, T, Tempel, W, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Botchkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2009-01-30
Release date:2009-02-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Hect Domain of Human HUWE1/MULE
To be Published
2PP3
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BU of 2pp3 by Molmil
Crystal structure of L-talarate/galactarate dehydratase mutant K197A liganded with Mg and L-glucarate
Descriptor: L-GLUCARIC ACID, L-talarate/galactarate dehydratase, MAGNESIUM ION
Authors:Fedorov, A.A, Fedorov, E.V, Yew, W.S, Gerlt, J.A, Almo, S.C.
Deposit date:2007-04-27
Release date:2007-08-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Evolution of enzymatic activities in the enolase superfamily: L-talarate/galactarate dehydratase from Salmonella typhimurium LT2.
Biochemistry, 46, 2007
3FWW
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BU of 3fww by Molmil
The crystal structure of the bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase from Yersinia pestis CO92
Descriptor: Bifunctional protein glmU
Authors:Zhang, R, Gu, M, Stam, J, Anderson, W, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2009-01-19
Release date:2009-03-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of the bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase from Yersinia pestis CO92
To be Published
8AK5
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BU of 8ak5 by Molmil
Human Sirt6 in complex with ADP-ribose and fragment pyroglutamic acid
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NAD-dependent protein deacetylase sirtuin-6, ...
Authors:You, W, Steegborn, C.
Deposit date:2022-07-29
Release date:2023-08-16
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
8AKB
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BU of 8akb by Molmil
Human Sirt6 in complex with ADP-ribose and fragment 4-nitrocatechol
Descriptor: 1,2-ETHANEDIOL, 4-NITROCATECHOL, DI(HYDROXYETHYL)ETHER, ...
Authors:You, W, Steegborn, C.
Deposit date:2022-07-29
Release date:2023-08-16
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
3KKW
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BU of 3kkw by Molmil
Crystal structure of His-tagged form of PA4794 protein
Descriptor: 1,2-ETHANEDIOL, Putative uncharacterized protein, SULFATE ION
Authors:Majorek, K.A, Chruszcz, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
Deposit date:2009-11-06
Release date:2009-11-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Double trouble-Buffer selection and His-tag presence may be responsible for nonreproducibility of biomedical experiments.
Protein Sci., 23, 2014
3UUD
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BU of 3uud by Molmil
Crystal structure of hERa-LBD (Y537S) in complex with estradiol
Descriptor: 1,2-ETHANEDIOL, ESTRADIOL, Estrogen receptor, ...
Authors:Delfosse, V, Grimaldi, M, Bourguet, W.
Deposit date:2011-11-28
Release date:2012-08-22
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and mechanistic insights into bisphenols action provide guidelines for risk assessment and discovery of bisphenol A substitutes.
Proc.Natl.Acad.Sci.USA, 109, 2012
8AKF
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BU of 8akf by Molmil
Human Sirt6 in complex with ADP-ribose and fragment 3-aminobenzamide
Descriptor: 1,2-ETHANEDIOL, 3-aminobenzamide, CHLORIDE ION, ...
Authors:You, W, Steegborn, C.
Deposit date:2022-07-29
Release date:2023-08-16
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
3KLC
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BU of 3klc by Molmil
Crystal structure of hyperthermophilic nitrilase
Descriptor: ACETIC ACID, BROMIDE ION, Beta ureidopropionase (Beta-alanine synthase), ...
Authors:Raczynska, J, Vorgias, C, Antranikian, G, Rypniewski, W.
Deposit date:2009-11-07
Release date:2010-11-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Crystallographic analysis of a thermoactive nitrilase.
J.Struct.Biol., 173, 2010
3V34
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BU of 3v34 by Molmil
Crystal structure of MCPIP1 conserved domain with magnesium ion in the catalytic center
Descriptor: MAGNESIUM ION, Ribonuclease ZC3H12A
Authors:Xu, J, Peng, W, Sun, Y, Wang, X, Xu, Y, Li, X, Gao, G, Rao, Z.
Deposit date:2011-12-12
Release date:2012-05-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:Structural study of MCPIP1 N-terminal conserved domain reveals a PIN-like RNase
Nucleic Acids Res., 40, 2012
5B18
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BU of 5b18 by Molmil
Crystal Structure of a Darunavir Resistant HIV-1 Protease
Descriptor: ACETATE ION, CHLORIDE ION, Protease
Authors:Suzuki, K, Ode, H, Nakashima, M, Sugiura, W, Watanabe, N, Suzuki, A, Iwatani, Y.
Deposit date:2015-11-30
Release date:2016-04-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Unique Flap Conformation in an HIV-1 Protease with High-Level Darunavir Resistance
Front Microbiol, 7, 2016
2KR7
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BU of 2kr7 by Molmil
solution structure of Helicobacter pylori SlyD
Descriptor: FKBP-type peptidyl-prolyl cis-trans isomerase slyD
Authors:Cheng, T, Li, H, Xia, W, Sze, K, Sun, H.
Deposit date:2009-12-07
Release date:2010-12-15
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:solution structure of Helicobacter pylori SlyD
To be Published
5B24
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BU of 5b24 by Molmil
The crystal structure of the nucleosome containing cyclobutane pyrimidine dimer
Descriptor: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Horikoshi, N, Tachiwana, H, Kagawa, W, Osakabe, A, Kurumizaka, H.
Deposit date:2015-12-31
Release date:2016-03-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Crystal structure of the nucleosome containing ultraviolet light-induced cyclobutane pyrimidine dimer
Biochem.Biophys.Res.Commun., 471, 2016
8AK6
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BU of 8ak6 by Molmil
Human Sirt6 in complex with ADP-ribose and fragment sulfamethoxazole
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NAD-dependent protein deacetylase sirtuin-6, ...
Authors:You, W, Steegborn, C.
Deposit date:2022-07-29
Release date:2023-08-16
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
8AK9
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BU of 8ak9 by Molmil
Human Sirt6 in complex with ADP-ribose and fragment Isatin
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:You, W, Steegborn, C.
Deposit date:2022-07-29
Release date:2023-08-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
8AKD
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BU of 8akd by Molmil
Human Sirt6 in complex with ADP-ribose and fragment 1-methyl-L-histidine
Descriptor: 4-METHYL-HISTIDINE, DI(HYDROXYETHYL)ETHER, NAD-dependent protein deacetylase sirtuin-6, ...
Authors:You, W, Steegborn, C.
Deposit date:2022-07-29
Release date:2023-08-16
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
3V33
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BU of 3v33 by Molmil
Crystal structure of MCPIP1 conserved domain with zinc-finger motif
Descriptor: Ribonuclease ZC3H12A
Authors:Xu, J, Peng, W, Sun, Y, Wang, X, Xu, Y, Li, X, Gao, G, Rao, Z.
Deposit date:2011-12-12
Release date:2012-05-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.005 Å)
Cite:Structural study of MCPIP1 N-terminal conserved domain reveals a PIN-like RNase
Nucleic Acids Res., 40, 2012
8AK7
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BU of 8ak7 by Molmil
Human Sirt6 in complex with ADP-ribose and fragment 6-O-methylguanine
Descriptor: 1,2-ETHANEDIOL, 6-O-methylguanine, CHLORIDE ION, ...
Authors:You, W, Steegborn, C.
Deposit date:2022-07-29
Release date:2023-08-16
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
8AKC
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BU of 8akc by Molmil
Human Sirt6 in complex with ADP-ribose and fragment 3-(acetylamino)thiophene-2-carboxylic acid
Descriptor: 3-(acetylamino)thiophene-2-carboxylic acid, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:You, W, Steegborn, C.
Deposit date:2022-07-29
Release date:2023-08-16
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
1QR9
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BU of 1qr9 by Molmil
INHIBITION OF HIV-1 INFECTIVITY BY THE GP41 CORE: ROLE OF A CONSERVED HYDROPHOBIC CAVITY IN MEMBRANE FUSION
Descriptor: GP41 ENVELOPE PROTEIN
Authors:Ji, H, Shu, W, Burling, F.T, Jiang, S.B, Lu, M.
Deposit date:1999-06-18
Release date:1999-11-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Inhibition of human immunodeficiency virus type 1 infectivity by the gp41 core: role of a conserved hydrophobic cavity in membrane fusion.
J.Virol., 73, 1999
2KQQ
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BU of 2kqq by Molmil
NMR structure of human insulin mutant gly-b8-d-ala, his-b10-asp, pro-b28-lys, lys-b29-pro, 20 structures
Descriptor: Insulin A chain, Insulin B chain
Authors:Hua, Q.X, Wan, Z.L, Zhao, M, Jia, W, Huang, K, Weiss, M.A.
Deposit date:2009-11-13
Release date:2010-11-24
Last modified:2021-10-13
Method:SOLUTION NMR
Cite:Structure and Dynamics of an Turn-Stabilize But Ina Insulin Analog.
To be Published
8AKA
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BU of 8aka by Molmil
Human Sirt6 in complex with ADP-ribose and fragment cis-resveratrol
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:You, W, Steegborn, C.
Deposit date:2022-07-29
Release date:2023-08-16
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
4AOE
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BU of 4aoe by Molmil
Biomphalaria glabrata Acetylcholine-binding protein type 2 (BgAChBP2)
Descriptor: ACETYLCHOLINE-BINDING PROTEIN TYPE 2
Authors:Saur, M, Moeller, V, Kapetanopoulos, K, Braukmann, S, Gebauer, W, Tenzer, S, Markl, J.
Deposit date:2012-03-26
Release date:2012-08-29
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Acetylcholine-Binding Protein in the Hemolymph of the Planorbid Snail Biomphalaria Glabrata is a Pentagonal Dodecahedron (60 Subunits)
Plos One, 7, 2012

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