3G1N
Catalytic domain of the human E3 ubiquitin-protein ligase HUWE1
Summary for 3G1N
Entry DOI | 10.2210/pdb3g1n/pdb |
Descriptor | E3 ubiquitin-protein ligase HUWE1, SODIUM ION (3 entities in total) |
Functional Keywords | alpha and beta protein (a + b), e3 ligase, hect domain, ubl-conjugation pathway, alternative splicing, chromosomal rearrangement, cytoplasm, differentiation, disease mutation, dna-binding, ligase, mental retardation, nucleus, phosphoprotein, ubl conjugation pathway, structural genomics, structural genomics consortium, sgc |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q7Z6Z7 |
Total number of polymer chains | 2 |
Total formula weight | 91102.98 |
Authors | Walker, J.R.,Qiu, L.,Li, Y.,Davis, T.,Tempel, W.,Weigelt, J.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Botchkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2009-01-30, release date: 2009-02-17, Last modification date: 2023-09-06) |
Primary citation | Walker, J.R.,Qiu, L.,Li, Y.,Davis, T.,Tempel, W.,Weigelt, J.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Botchkarev, A.,Dhe-Paganon, S. Hect Domain of Human HUWE1/MULE To be Published, |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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