3G1N

Catalytic domain of the human E3 ubiquitin-protein ligase HUWE1

Summary for 3G1N

• Entry DOI: 10.2210/pdb3g1n/pdb
• Descriptor: E3 ubiquitin-protein ligase HUWE1, SODIUM ION (3 entities in total)
• Functional Keywords: alpha and beta protein (a + b), e3 ligase, hect domain, ubl-conjugation pathway, alternative splicing, chromosomal rearrangement, cytoplasm, differentiation, disease mutation, dna-binding, ligase, mental retardation, nucleus, phosphoprotein, ubl conjugation pathway, structural genomics, structural genomics consortium, sgc
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q7Z6Z7
• Total number of polymer chains: 2
• Total formula weight: 91102.98

Authors

Walker, J.R.,Qiu, L.,Li, Y.,Davis, T.,Tempel, W.,Weigelt, J.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Botchkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2009-01-30, release date: 2009-02-17, Last modification date: 2023-09-06)

• Primary citation: Walker, J.R.,Qiu, L.,Li, Y.,Davis, T.,Tempel, W.,Weigelt, J.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Botchkarev, A.,Dhe-Paganon, S.; Hect Domain of Human HUWE1/MULE; To be Published,

Experimental method

X-RAY DIFFRACTION (2.6 Å)