5B18
Crystal Structure of a Darunavir Resistant HIV-1 Protease
Summary for 5B18
| Entry DOI | 10.2210/pdb5b18/pdb |
| Descriptor | Protease, CHLORIDE ION, ACETATE ION, ... (4 entities in total) |
| Functional Keywords | hiv-1 protease, drug resistance, darunavir, flap, hydrolase |
| Biological source | Human immunodeficiency virus 1 |
| Total number of polymer chains | 4 |
| Total formula weight | 44019.53 |
| Authors | Suzuki, K.,Ode, H.,Nakashima, M.,Sugiura, W.,Watanabe, N.,Suzuki, A.,Iwatani, Y. (deposition date: 2015-11-30, release date: 2016-04-13, Last modification date: 2023-11-08) |
| Primary citation | Nakashima, M.,Ode, H.,Suzuki, K.,Fujino, M.,Maejima, M.,Kimura, Y.,Masaoka, T.,Hattori, J.,Matsuda, M.,Hachiya, A.,Yokomaku, Y.,Suzuki, A.,Watanabe, N.,Sugiura, W.,Iwatani, Y. Unique Flap Conformation in an HIV-1 Protease with High-Level Darunavir Resistance Front Microbiol, 7:61-61, 2016 Cited by PubMed: 26870021DOI: 10.3389/fmicb.2016.00061 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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