6R38
 
 | | T. brucei FPPS in complex with 2-(2,5-dichlorobenzo[b]thiophen-3-yl)acetic acid | | 分子名称: | 2-[2,5-bis(chloranyl)-1-benzothiophen-3-yl]ethanoic acid, DIMETHYL SULFOXIDE, Farnesyl pyrophosphate synthase | | 著者 | Muenzker, L, Petrick, J.K, Schleberger, C, Jahnke, W. | | 登録日 | 2019-03-19 | | 公開日 | 2020-04-08 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Targeting Trypanosoma brucei FPPS by Fragment-based drug discovery
Thesis, 2019
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7XAY
 | | Crystal structure of Hat1-Hat2-Asf1-H3-H4 | | 分子名称: | COENZYME A, Histone H3, Histone H4, ... | | 著者 | Yue, Y, Yang, W.S, Xu, R.M. | | 登録日 | 2022-03-19 | | 公開日 | 2022-05-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Topography of histone H3-H4 interaction with the Hat1-Hat2 acetyltransferase complex.
Genes Dev., 36, 2022
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6WZZ
 | | GID4 in complex with VGLWKS peptide | | 分子名称: | Glucose-induced degradation protein 4 homolog, UNKNOWN ATOM OR ION, VGLWKS peptide | | 著者 | Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2020-05-14 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Recognition of nonproline N-terminal residues by the Pro/N-degron pathway.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6ZGZ
 | | Structure of human galactokinase 1 bound with 2-(4-chlorophenyl)-N-(pyrimidin-2-yl)acetamide | | 分子名称: | 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, Galactokinase, beta-D-galactopyranose, ... | | 著者 | Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W. | | 登録日 | 2020-06-20 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Fragment Screening Reveals Starting Points for Rational Design of Galactokinase 1 Inhibitors to Treat Classic Galactosemia.
Acs Chem.Biol., 16, 2021
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7LJC
 | | Allosteric modulator LY3154207 binding to SKF-81297-bound dopamine receptor 1 in complex with miniGs protein | | 分子名称: | (1R)-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, 2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, ... | | 著者 | Zhuang, Y, Krumm, B, Zhang, H, Zhou, X.E, Wang, Y, Guo, J, Huang, X.-P, Liu, Y, Wang, L, Cheng, X, Jiang, Y, Jiang, H, Melcher, K, Zhang, C, Yi, W, Roth, B.L, Zhang, Y, Xu, H.E. | | 登録日 | 2021-01-28 | | 公開日 | 2021-03-03 | | 最終更新日 | 2021-05-12 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor.
Cell Res., 31, 2021
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7LJD
 | | Allosteric modulator LY3154207 binding to dopamine-bound dopamine receptor 1 in complex with miniGs protein | | 分子名称: | 2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, D(1A) dopamine receptor, ... | | 著者 | Zhuang, Y, Krumm, B, Zhang, H, Zhou, X.E, Wang, Y, Guo, J, Huang, X.-P, Liu, Y, Wang, L, Cheng, X, Jiang, Y, Jiang, H, Melcher, K, Zhang, C, Yi, W, Roth, B.L, Zhang, Y, Xu, H.E. | | 登録日 | 2021-01-28 | | 公開日 | 2021-03-03 | | 最終更新日 | 2021-05-12 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor.
Cell Res., 31, 2021
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7X9R
 | | Crystal structure of the antirepressor GmaR | | 分子名称: | Glycosyl transferase family 2 | | 著者 | Cho, S.Y, Na, H.W, Oh, H.B, Kwak, Y.M, Song, W.S, Park, S.C, Yoon, S.I. | | 登録日 | 2022-03-16 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural basis of flagellar motility regulation by the MogR repressor and the GmaR antirepressor in Listeria monocytogenes.
Nucleic Acids Res., 50, 2022
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7X9S
 | | Crystal structure of a complex between the antirepressor GmaR and the transcriptional repressor MogR | | 分子名称: | GmaR, Motility gene repressor MogR | | 著者 | Cho, S.Y, Na, H.W, Oh, H.B, Kwak, Y.M, Song, W.S, Park, S.C, Yoon, S.I. | | 登録日 | 2022-03-16 | | 公開日 | 2022-11-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | | 主引用文献 | Structural basis of flagellar motility regulation by the MogR repressor and the GmaR antirepressor in Listeria monocytogenes.
Nucleic Acids Res., 50, 2022
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7XFP
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7W9Z
 | | Crystal structure of Bacillus subtilis YugJ in complex with NADP and nitrate | | 分子名称: | Iron-containing alcohol dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NITRATE ION | | 著者 | Cho, H.Y, Nam, M.S, Hong, H.J, Song, W.S, Yoon, S.I. | | 登録日 | 2021-12-11 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural and Biochemical Analysis of the Furan Aldehyde Reductase YugJ from Bacillus subtilis.
Int J Mol Sci, 23, 2022
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7W9X
 | | Crystal structure of Bacillus subtilis YugJ in complex with nickel | | 分子名称: | Iron-containing alcohol dehydrogenase, NICKEL (II) ION | | 著者 | Cho, H.Y, Nam, M.S, Hong, H.J, Song, W.S, Yoon, S.I. | | 登録日 | 2021-12-11 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.151 Å) | | 主引用文献 | Structural and Biochemical Analysis of the Furan Aldehyde Reductase YugJ from Bacillus subtilis.
Int J Mol Sci, 23, 2022
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7W9Y
 | | Crystal structure of Bacillus subtilis YugJ in complex with NADP and nickel | | 分子名称: | Iron-containing alcohol dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NICKEL (II) ION | | 著者 | Cho, H.Y, Nam, M.S, Hong, H.J, Song, W.S, Yoon, S.I. | | 登録日 | 2021-12-11 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Structural and Biochemical Analysis of the Furan Aldehyde Reductase YugJ from Bacillus subtilis.
Int J Mol Sci, 23, 2022
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7V6D
 | | Structure of lipase B from Lasiodiplodia theobromae | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Lipase B | | 著者 | Xue, B, Zhang, H.F, Nguyen, G.K.T, Yew, W.S. | | 登録日 | 2021-08-20 | | 公開日 | 2021-10-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A Novel Lipase from Lasiodiplodia theobromae Efficiently Hydrolyses C8-C10 Methyl Esters for the Preparation of Medium-Chain Triglycerides' Precursors.
Int J Mol Sci, 22, 2021
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8EJ4
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7C9V
 | | E30 F-particle in complex with FcRn | | 分子名称: | Beta-2-microglobulin, IgG receptor FcRn large subunit p51, MYRISTIC ACID, ... | | 著者 | Wang, K, Zhu, L, Sun, Y, Li, M, Zhao, X, Cui, L, Zhang, L, Gao, G, Zhai, W, Zhu, F, Rao, Z, Wang, X. | | 登録日 | 2020-06-07 | | 公開日 | 2020-07-29 | | 最終更新日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structures of Echovirus 30 in complex with its receptors inform a rational prediction for enterovirus receptor usage.
Nat Commun, 11, 2020
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7C3M
 | | Structure of FERM protein | | 分子名称: | Fermitin family homolog 3,Fermitin family homolog 3,Fermitin family homolog 3 | | 著者 | Bu, W, Loh, Z.Y, Jin, S, Basu, S, Ero, R, Park, J.E, Yan, X, Wang, M, Sze, S.K, Tan, S.M, Gao, Y.G. | | 登録日 | 2020-05-13 | | 公開日 | 2020-06-03 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structural basis of human full-length kindlin-3 homotrimer in an auto-inhibited state.
Plos Biol., 18, 2020
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7C7E
 | | Crystal structure of C terminal domain of Escherichia coli DgoR | | 分子名称: | Putative DNA-binding transcriptional regulator, SULFATE ION, TRIETHYLENE GLYCOL, ... | | 著者 | Lin, W. | | 登録日 | 2020-05-25 | | 公開日 | 2021-01-20 | | 実験手法 | X-RAY DIFFRACTION (2.047 Å) | | 主引用文献 | Structural and Functional Analyses of the Transcription Repressor DgoR From Escherichia coli Reveal a Divalent Metal-Containing D-Galactonate Binding Pocket.
Front Microbiol, 11, 2020
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7CJ3
 | | Crystal structure of the transmembrane domain of Salpingoeca rosetta rhodopsin phosphodiesterase | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Phosphodiesterase, RETINAL | | 著者 | Ikuta, T, Shihoya, W, Yamashita, K, Nureki, O. | | 登録日 | 2020-07-09 | | 公開日 | 2020-11-25 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural insights into the mechanism of rhodopsin phosphodiesterase.
Nat Commun, 11, 2020
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7CRC
 | | Cryo-EM structure of plant NLR RPP1 tetramer in complex with ATR1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Avirulence protein ATR1, ... | | 著者 | Ma, S.C, Lapin, D, Liu, L, Sun, Y, Song, W, Zhang, X.X, Logemann, E, Yu, D.L, Wang, J, Jirschitzka, J, Han, Z.F, SchulzeLefert, P, Parker, J.E, Chai, J.J. | | 登録日 | 2020-08-13 | | 公開日 | 2020-12-16 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | | 主引用文献 | Direct pathogen-induced assembly of an NLR immune receptor complex to form a holoenzyme.
Science, 370, 2020
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7C9S
 | | Echovirus 30 F-particle | | 分子名称: | SPHINGOSINE, VP1, VP2, ... | | 著者 | Wang, K, Sun, Y, Zhu, L, Li, M, Zhao, X, Cui, L, Zhang, L, Gao, G, Zhai, W, Zhu, F, Rao, Z, Wang, X. | | 登録日 | 2020-06-07 | | 公開日 | 2020-07-29 | | 最終更新日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structures of Echovirus 30 in complex with its receptors inform a rational prediction for enterovirus receptor usage.
Nat Commun, 11, 2020
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7CSZ
 | | Crystal structure of the N-terminal tandem RRM domains of RBM45 in complex with single-stranded DNA | | 分子名称: | DNA (5'-D(*CP*GP*AP*CP*GP*GP*GP*AP*CP*GP*C)-3'), RNA-binding protein 45 | | 著者 | Chen, X, Yang, Z, Wang, W, Wang, M. | | 登録日 | 2020-08-17 | | 公開日 | 2021-02-03 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for RNA recognition by the N-terminal tandem RRM domains of human RBM45.
Nucleic Acids Res., 49, 2021
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7CUN
 | | The structure of human Integrator-PP2A complex | | 分子名称: | Integrator complex subunit 1, Integrator complex subunit 11, Integrator complex subunit 2, ... | | 著者 | Zheng, H, Qi, Y, Liu, W, Li, J, Wang, J, Xu, Y. | | 登録日 | 2020-08-23 | | 公開日 | 2020-11-25 | | 最終更新日 | 2020-12-09 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase.
Science, 370, 2020
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7CM2
 | | The Crystal Structure of human USP7 USP domain from Biortus | | 分子名称: | GLYCEROL, Ubiquitin carboxyl-terminal hydrolase 7 | | 著者 | Wang, F, Cheng, W, Lv, Z, Lin, D, Zhu, B, Miao, Q, Bao, X, Shang, H. | | 登録日 | 2020-07-24 | | 公開日 | 2020-08-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | The Crystal Structure of human USP7 USP domain from Biortus.
To Be Published
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7C9W
 | | E30 F-particle in complex with CD55 | | 分子名称: | Complement decay-accelerating factor, MYRISTIC ACID, SPHINGOSINE, ... | | 著者 | Wang, K, Zhu, L, Sun, Y, Li, M, Zhao, X, Cui, L, Zhang, L, Gao, G, Zhai, W, Zhu, F, Rao, Z, Wang, X. | | 登録日 | 2020-06-07 | | 公開日 | 2020-07-29 | | 最終更新日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structures of Echovirus 30 in complex with its receptors inform a rational prediction for enterovirus receptor usage.
Nat Commun, 11, 2020
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7CML
 | | The Crystal Structure of human JNK2 from Biortus. | | 分子名称: | Mitogen-activated protein kinase 9 | | 著者 | Wang, F, Lin, D, Cheng, W, Miao, Q, Huang, Y, Shang, H. | | 登録日 | 2020-07-28 | | 公開日 | 2020-08-12 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | The Crystal Structure of human JNK2 from Biortus.
To Be Published
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