6R38

T. brucei FPPS in complex with 2-(2,5-dichlorobenzo[b]thiophen-3-yl)acetic acid

Summary for 6R38

Entry DOI	10.2210/pdb6r38/pdb
Descriptor	Farnesyl pyrophosphate synthase, 2-[2,5-bis(chloranyl)-1-benzothiophen-3-yl]ethanoic acid, DIMETHYL SULFOXIDE, ... (4 entities in total)
Functional Keywords	sterol biosynthesis, farnesyl diphosphate synthase, trypanosoma brucei, homodimer, transferase
Biological source	Trypanosoma brucei
Total number of polymer chains	1
Total formula weight	42508.47
Authors	Muenzker, L.,Petrick, J.K.,Schleberger, C.,Jahnke, W. (deposition date: 2019-03-19, release date: 2020-04-08, Last modification date: 2024-01-24)
Primary citation	Muenzker, L.,Wolfgang, J. Targeting Trypanosoma brucei FPPS by Fragment-based drug discovery Thesis, 2019 Cited by DOI: 10.17192/z2019.0500 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.33 Å)

Structure validation