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6R38

T. brucei FPPS in complex with 2-(2,5-dichlorobenzo[b]thiophen-3-yl)acetic acid

Functional Information from GO Data
ChainGOidnamespacecontents
A0004659molecular_functionprenyltransferase activity
A0008299biological_processisoprenoid biosynthetic process
A0016740molecular_functiontransferase activity
A0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues7
Detailsbinding site for residue JQE A 401
ChainResidue
AASN49
AARG50
ATHR217
APHE251
ALEU358
ALYS361
ATHR362

site_idAC2
Number of Residues6
Detailsbinding site for residue DMS A 402
ChainResidue
ALYS212
AGLN252
AASP256
ACYS279
AASP175
AILE208

Functional Information from PROSITE/UniProt
site_idPS00444
Number of Residues13
DetailsPOLYPRENYL_SYNTHASE_2 Polyprenyl synthases signature 2. MGeyFQVqDDVmD
ChainResidueDetails
AMET247-ASP259

site_idPS00723
Number of Residues15
DetailsPOLYPRENYL_SYNTHASE_1 Polyprenyl synthases signature 1. LVeDDim..DnsvtRRG
ChainResidueDetails
ALEU100-GLY114

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PDB entries from 2024-07-17

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