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PDB: 12929 件

5JNA
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Crystal structure for the complex of human carbonic anhydrase IV and topiramate
分子名称: ACETATE ION, Carbonic anhydrase 4, GLYCEROL, ...
著者Chen, Z, Waheed, A, Di Cera, E, Sly, W.S.
登録日2016-04-29
公開日2017-05-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV.
Eur. Biophys. J., 47, 2018
7EVM
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BU of 7evm by Molmil
Cryo-EM structure of the compound 2-bound human GLP-1 receptor-Gs complex
分子名称: CHOLESTEROL, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Cong, Z, Chen, L, Ma, H, Zhou, Q, Zou, X, Ye, C, Dai, A, Liu, Q, Huang, W, Sun, X, Wang, X, Xu, P, Zhao, L, Xia, T, Zhong, W, Yang, D, Xu, H.E, Zhang, Y, Wang, M.
登録日2021-05-21
公開日2021-08-11
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor.
Nat Commun, 12, 2021
3F87
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An alpha/beta-Peptide Helix Bundle with a Pure beta-Amino Acid Core and a Distinctive Quarternary Structure: GCN4pLI derivative with beta residues at a and d heptad positions - higher symmetry crystal
分子名称: GCN4pLI-betaAD, IODIDE ION
著者Giuliano, M.W, Horne, W.S, Gellman, S.H.
登録日2008-11-11
公開日2009-07-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献An alpha/beta-peptide helix bundle with a pure beta3-amino acid core and a distinctive quaternary structure.
J.Am.Chem.Soc., 131, 2009
1MUS
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BU of 1mus by Molmil
crystal structure of Tn5 transposase complexed with resolved outside end DNA
分子名称: 1,2-ETHANEDIOL, DNA non-transferred strand, DNA transferred strand, ...
著者Holden, H.M, Thoden, J.B, Steiniger-White, M, Reznikoff, W.S, Lovell, S, Rayment, I.
登録日2002-09-24
公開日2002-09-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure/function insights into Tn5 transposition.
Curr.Opin.Struct.Biol., 14, 2004
8ERZ
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BU of 8erz by Molmil
Backbone modifications in the inter-helix loop of designed miniprotein oPPalpha: Aib10Gly11 turn
分子名称: Designed miniprotein oPPalpha: Aib10Gly11 turn
著者Harmon, T.W, Horne, W.S.
登録日2022-10-13
公開日2023-04-05
最終更新日2023-06-28
実験手法SOLUTION NMR
主引用文献Protein Backbone Alteration in Non-Hairpin beta-Turns: Impacts on Tertiary Folded Structure and Folded Stability.
Chembiochem, 24, 2023
8ES1
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BU of 8es1 by Molmil
Backbone modifications in the inter-helix loop of designed miniprotein oPPalpha: deltaOrn10-11 turn
分子名称: Designed miniprotein oPPalpha: deltaOrn10-11 turn
著者Harmon, T.W, Horne, W.S.
登録日2022-10-13
公開日2023-04-05
最終更新日2023-06-28
実験手法SOLUTION NMR
主引用文献Protein Backbone Alteration in Non-Hairpin beta-Turns: Impacts on Tertiary Folded Structure and Folded Stability.
Chembiochem, 24, 2023
8ERY
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BU of 8ery by Molmil
Backbone modifications in the inter-helix loop of designed miniprotein oPPalpha: Asp10Asn11 turn
分子名称: Designed miniprotein oPPalpha: Asp10Asn11 turn
著者Harmon, T.W, Horne, W.S.
登録日2022-10-13
公開日2023-04-05
実験手法SOLUTION NMR
主引用文献Protein Backbone Alteration in Non-hairpin beta-Turns: Impacts on Tertiary Folded Structure and Folded Stability.
Chembiochem, 2023
8ES2
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BU of 8es2 by Molmil
Backbone modifications in the inter-helix loop of designed miniprotein oPPalpha: Aib10Asn11 turn
分子名称: Designed miniprotein oPPalpha: Aib10Asn11 turn
著者Harmon, T.W, Horne, W.S.
登録日2022-10-13
公開日2023-04-05
最終更新日2023-06-28
実験手法SOLUTION NMR
主引用文献Protein Backbone Alteration in Non-Hairpin beta-Turns: Impacts on Tertiary Folded Structure and Folded Stability.
Chembiochem, 24, 2023
8ES3
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Backbone modifications in the inter-helix loop of designed miniprotein oPPalpha: DPro10Pro11 turn
分子名称: Designed miniprotein oPPalpha: DPro10Pro11 turn
著者Harmon, T.W, Horne, W.S.
登録日2022-10-13
公開日2023-04-05
最終更新日2023-06-28
実験手法SOLUTION NMR
主引用文献Protein Backbone Alteration in Non-Hairpin beta-Turns: Impacts on Tertiary Folded Structure and Folded Stability.
Chembiochem, 24, 2023
8ES0
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BU of 8es0 by Molmil
Backbone modifications in the inter-helix loop of designed miniprotein oPPalpha: DPro10Gly11 turn
分子名称: Designed miniprotein oPPalpha: DPro10Gly11 turn
著者Harmon, T.W, Horne, W.S.
登録日2022-10-13
公開日2023-04-05
最終更新日2023-06-28
実験手法SOLUTION NMR
主引用文献Protein Backbone Alteration in Non-Hairpin beta-Turns: Impacts on Tertiary Folded Structure and Folded Stability.
Chembiochem, 24, 2023
4NIZ
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BU of 4niz by Molmil
GCN4-p1 single Val9 to aminobutyric acid mutant
分子名称: GLYCEROL, General control protein GCN4
著者Oshaben, K.M, Horne, W.S.
登録日2013-11-08
公開日2014-08-20
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Tuning assembly size in Peptide-based supramolecular polymers by modulation of subunit association affinity.
Biomacromolecules, 15, 2014
4NJ2
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BU of 4nj2 by Molmil
GCN4-p1 triple Val9, 23,30 to Ile mutant
分子名称: GLYCEROL, General control protein GCN4
著者Oshaben, K.M, Horne, W.S.
登録日2013-11-08
公開日2014-08-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Tuning assembly size in Peptide-based supramolecular polymers by modulation of subunit association affinity.
Biomacromolecules, 15, 2014
3F50
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BU of 3f50 by Molmil
HIV gp41 six-helix bundle composed of an alpha/beta-peptide analogue of the CHR domain in complex with an NHR domain alpha-peptide
分子名称: Envelope glycoprotein gp160, GLYCEROL, alpha/beta-peptide analogue of the HIV gp41 CHR domain
著者Horne, W.S, Gellman, S.H.
登録日2008-11-03
公開日2009-09-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers
Proc.Natl.Acad.Sci.USA, 106, 2009
1SO6
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Crystal structure of E112Q/H136A double mutant of 3-keto-L-gulonate 6-phosphate decarboxylase with bound L-threonohydroxamate 4-phosphate
分子名称: 3-keto-L-gulonate 6-phosphate decarboxylase, L-THREONOHYDROXAMATE 4-PHOSPHATE, MAGNESIUM ION
著者Wise, E.L, Yew, W.S, Gerlt, J.A, Rayment, I.
登録日2004-03-12
公開日2004-06-08
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献Evolution of Enzymatic Activities in the Orotidine 5'-Monophosphate Decarboxylase Suprafamily: Crystallographic Evidence for a Proton Relay System in the Active Site of 3-Keto-l-gulonate 6-Phosphate Decarboxylase(,)
Biochemistry, 43, 2004
1SO5
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BU of 1so5 by Molmil
Crystal structure of E112Q mutant of 3-keto-L-gulonate 6-phosphate decarboxylase with bound L-threonohydroxamate 4-phosphate
分子名称: 3-keto-L-gulonate 6-phosphate decarboxylase, L-THREONOHYDROXAMATE 4-PHOSPHATE, MAGNESIUM ION
著者Wise, E.L, Yew, W.S, Gerlt, J.A, Rayment, I.
登録日2004-03-12
公開日2004-06-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Evolution of Enzymatic Activities in the Orotidine 5'-Monophosphate Decarboxylase Suprafamily: Crystallographic Evidence for a Proton Relay System in the Active Site of 3-Keto-l-gulonate 6-Phosphate Decarboxylase(,)
Biochemistry, 43, 2004
3F4Y
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HIV gp41 six-helix bundle containing a mutant CHR alpha-peptide sequence
分子名称: Envelope glycoprotein gp160, Mutant peptide derived from HIV gp41 CHR domain
著者Horne, W.S, Gellman, S.H.
登録日2008-11-03
公開日2009-09-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers
Proc.Natl.Acad.Sci.USA, 106, 2009
1SO3
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BU of 1so3 by Molmil
Crystal structure of H136A mutant of 3-keto-L-gulonate 6-phosphate decarboxylase with bound L-threonohydroxamate 4-phosphate
分子名称: 3-keto-L-gulonate 6-phosphate decarboxylase, L-THREONOHYDROXAMATE 4-PHOSPHATE, MAGNESIUM ION
著者Wise, E.L, Yew, W.S, Gerlt, J.A, Rayment, I.
登録日2004-03-12
公開日2004-06-08
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Evolution of Enzymatic Activities in the Orotidine 5'-Monophosphate Decarboxylase Suprafamily: Crystallographic Evidence for a Proton Relay System in the Active Site of 3-Keto-l-gulonate 6-Phosphate Decarboxylase(,)
Biochemistry, 43, 2004
7W1F
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BU of 7w1f by Molmil
Crystal structure of the dNTP triphosphohydrolase PA1124 from Pseudomonas aeruginosa
分子名称: NICKEL (II) ION, Probable deoxyguanosinetriphosphate triphosphohydrolase
著者Oh, H.B, Song, W.S, Lee, K.C, Park, S.C, Yoon, S.I.
登録日2021-11-19
公開日2022-03-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural analysis of the dNTP triphosphohydrolase PA1124 from Pseudomonas aeruginosa.
Biochem.Biophys.Res.Commun., 589, 2022
7WKV
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BU of 7wkv by Molmil
Crystal structure of human ALKBH5 in complex with 2-oxoglutarate (2OG) and m6A-containing ssRNA
分子名称: 2-OXOGLUTARIC ACID, MANGANESE (II) ION, RNA (5'-R(P*GP*GP*(6MZ)P*C)-3'), ...
著者Kaur, S, McDonough, M.A, Schofield, C.J, Aik, W.S.
登録日2022-01-11
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mechanisms of substrate recognition and N6-methyladenosine demethylation revealed by crystal structures of ALKBH5-RNA complexes.
Nucleic Acids Res., 50, 2022
1SO4
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Crystal structure of K64A mutant of 3-keto-L-gulonate 6-phosphate decarboxylase with bound L-threonohydroxamate 4-phosphate
分子名称: 3-keto-L-gulonate 6-phosphate decarboxylase, L-THREONOHYDROXAMATE 4-PHOSPHATE, MAGNESIUM ION
著者Wise, E.L, Yew, W.S, Gerlt, J.A, Rayment, I.
登録日2004-03-12
公開日2004-06-08
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Evolution of Enzymatic Activities in the Orotidine 5'-Monophosphate Decarboxylase Suprafamily: Crystallographic Evidence for a Proton Relay System in the Active Site of 3-Keto-l-gulonate 6-Phosphate Decarboxylase(,)
Biochemistry, 43, 2004
1SHC
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SHC PTB DOMAIN COMPLEXED WITH A TRKA RECEPTOR PHOSPHOPEPTIDE, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: SHC, TRKA RECEPTOR PHOSPHOPEPTIDE
著者Zhou, M.-M, Ravichandran, K.S, Olejniczak, E.T, Petros, A.M, Meadows, R.P, Sattler, M, Harlan, J.E, Wade, W.S, Burakoff, S.J, Fesik, S.W.
登録日1996-03-27
公開日1997-05-15
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Structure and ligand recognition of the phosphotyrosine binding domain of Shc.
Nature, 378, 1995
1SQ0
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Crystal Structure of the Complex of the Wild-type Von Willebrand Factor A1 domain and Glycoprotein Ib alpha at 2.6 Angstrom Resolution
分子名称: Platelet glycoprotein Ib alpha chain (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (CD42B-alpha) (CD42B) [Contains: Glycocalicin], Von Willebrand factor (vWF) [Contains: Von Willebrand antigen II]
著者Dumas, J.J, Kumar, R, McDonagh, T, Sullivan, F, Stahl, M.L, Somers, W.S, Mosyak, L.
登録日2004-03-17
公開日2004-04-13
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the wild-type von Willebrand factor A1-glycoprotein Ibalpha complex reveals conformation differences with a complex bearing von Willebrand disease mutations
J.Biol.Chem., 279, 2004
4OZB
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Backbone Modifications in the Protein GB1 Helix: beta-ACPC24, beta-3-Lys28, beta-3-Lys31, beta-ACPC35
分子名称: GLYCEROL, Streptococcal Protein GB1 Backbone Modified Variant: beta-ACPC24, beta-3-Lys28, ...
著者Reinert, Z.E, Horne, W.S.
登録日2014-02-14
公開日2014-07-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Folding Thermodynamics of Protein-Like Oligomers with Heterogeneous Backbones.
Chem Sci, 5, 2014
5N29
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An improved model of the Trypanosoma brucei CTP synthase glutaminase domain:acivicin complex.
分子名称: CHLORIDE ION, CTP synthase
著者de Souza, J, Dawson, A, Hunter, W.
登録日2017-02-07
公開日2017-04-05
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献An Improved Model of the Trypanosoma brucei CTP Synthetase Glutaminase Domain-Acivicin Complex.
ChemMedChem, 12, 2017
4OZC
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Backbone Modifications in the Protein GB1 Helix and Loops: beta-ACPC21, beta-ACPC24, beta-3-Lys28, beta-3-Lys31, beta-ACPC35, beta-ACPC40
分子名称: GLYCEROL, SULFATE ION, Streptococcal Protein GB1 Backbone Modified Variant: beta-ACPC21, ...
著者Reinert, Z.E, Horne, W.S.
登録日2014-02-14
公開日2014-07-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Folding Thermodynamics of Protein-Like Oligomers with Heterogeneous Backbones.
Chem Sci, 5, 2014

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件を2024-08-07に公開中

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