1AFR
 
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6L7Z
 | | Solution NMR structure of the N-terminal immunoglobulin variable domain of BTNL2 | | 分子名称: | Butyrophilin-like protein 2 | | 著者 | Basak, A.J, Lee, W, Samanta, D, De, S. | | 登録日 | 2019-11-03 | | 公開日 | 2020-10-14 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Insights into N-terminal IgV Domain of BTNL2, a T Cell Inhibitory Molecule, Suggests a Non-canonical Binding Interface for Its Putative Receptors.
J.Mol.Biol., 432, 2020
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6L8R
 | | membrane-bound PD-L1-CD | | 分子名称: | Programmed cell death 1 ligand 1 | | 著者 | Maorong, W, Cao, Y, Bin, W, Bo, O. | | 登録日 | 2019-11-07 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | PD-L1 degradation is regulated by electrostatic membrane association of its cytoplasmic domain.
Nat Commun, 12, 2021
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6KQV
 | | Solution Structure of the UbL Domain of USP19 | | 分子名称: | Ubiquitin carboxyl-terminal hydrolase 19 | | 著者 | Xue, W, Hu, H.Y. | | 登録日 | 2019-08-19 | | 公開日 | 2020-08-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Domain interactions reveal auto-inhibition of the deubiquitinating enzyme USP19 and its activation by HSP90 in the modulation of huntingtin aggregation.
Biochem.J., 477, 2020
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5OE6
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1A3X
 | | PYRUVATE KINASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH PG, MN2+ AND K+ | | 分子名称: | 2-PHOSPHOGLYCOLIC ACID, MANGANESE (II) ION, POTASSIUM ION, ... | | 著者 | Jurica, M.S, Mesecar, A, Heath, P.J, Shi, W, Nowak, T, Stoddard, B.L. | | 登録日 | 1998-01-26 | | 公開日 | 1998-05-27 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The allosteric regulation of pyruvate kinase by fructose-1,6-bisphosphate.
Structure, 6, 1998
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6LND
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5BQT
 | | Structure of TrmBL2, an archaeal chromatin protein, shows a novel mode of DNA binding. | | 分子名称: | CALCIUM ION, Putative HTH-type transcriptional regulator TrmBL2 | | 著者 | Ahmad, M.U, Diederichs, K, Welte, W. | | 登録日 | 2015-05-29 | | 公開日 | 2015-09-02 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Insights into Nonspecific Binding of DNA by TrmBL2, an Archaeal Chromatin Protein.
J.Mol.Biol., 427, 2015
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1AH1
 | | CTLA-4, NMR, 20 STRUCTURES | | 分子名称: | CTLA-4, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Metzler, W.J, Bajorath, J, Fenderson, W, Shaw, S.-Y, Peach, R, Constantine, K.L, Naemura, J, Leytze, G, Lavoie, T.B, Mueller, L, Linsley, P.S. | | 登録日 | 1997-04-11 | | 公開日 | 1998-04-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of human CTLA-4 and delineation of a CD80/CD86 binding site conserved in CD28.
Nat.Struct.Biol., 4, 1997
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1AFV
 | | HIV-1 CAPSID PROTEIN (P24) COMPLEX WITH FAB25.3 | | 分子名称: | ANTIBODY FAB25.3 FRAGMENT (HEAVY CHAIN), ANTIBODY FAB25.3 FRAGMENT (LIGHT CHAIN), HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 CAPSID PROTEIN, ... | | 著者 | Momany, C, Kovari, L.C, Prongay, A.J, Keller, W, Gitti, R.K, Lee, B.M, Gorbalenya, A.E, Tong, L, Mcclure, J, Ehrlich, L.S, Summers, M.F, Carter, C, Rossmann, M.G. | | 登録日 | 1997-03-14 | | 公開日 | 1997-08-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Crystal structure of dimeric HIV-1 capsid protein.
Nat.Struct.Biol., 3, 1996
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1A6S
 | | M-DOMAIN FROM GAG POLYPROTEIN OF ROUS SARCOMA VIRUS, NMR, 20 STRUCTURES | | 分子名称: | GAG POLYPROTEIN | | 著者 | Mcdonnell, J.M, Fushman, D, Cahill, S.M, Zhou, W, Wolven, A, Wilson, C.B, Nelle, T.D, Resh, M.D, Wills, J, Cowburn, D. | | 登録日 | 1998-03-02 | | 公開日 | 1998-10-14 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and dynamics of the bioactive retroviral M domain from Rous sarcoma virus
J.Mol.Biol., 279, 1998
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6LXD
 | | Pri-miRNA bound DROSHA-DGCR8 complex | | 分子名称: | Microprocessor complex subunit DGCR8, RNA (102-mer), Ribonuclease 3, ... | | 著者 | Jin, W, Wang, J, Liu, C.P, Wang, H.W, Xu, R.M. | | 登録日 | 2020-02-10 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural Basis for pri-miRNA Recognition by Drosha.
Mol.Cell, 78, 2020
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1A69
 | | PURINE NUCLEOSIDE PHOSPHORYLASE IN COMPLEX WITH FORMYCIN B AND SULPHATE (PHOSPHATE) | | 分子名称: | FORMYCIN B, PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION | | 著者 | Koellner, G, Luic, M, Shugar, D, Saenger, W, Bzowska, A. | | 登録日 | 1998-03-08 | | 公開日 | 1998-10-14 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of the ternary complex of E. coli purine nucleoside phosphorylase with formycin B, a structural analogue of the substrate inosine, and phosphate (Sulphate) at 2.1 A resolution.
J.Mol.Biol., 280, 1998
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6LK3
 | | The Functional Characterization and Crystal Structure of Type II Peptidyl Carrier Protein ColA1a in Collismycins Biosynthesis | | 分子名称: | Putative free-standing acyl carrier protein | | 著者 | Ma, X.Y, Wang, G.Y, Liu, T, Chi, C.B, Zhang, Z.Y, Yang, D.H, Liu, W, Ma, M. | | 登録日 | 2019-12-18 | | 公開日 | 2020-10-28 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The functional characterization and crystal structure of type II peptidyl carrier protein ColA1a in collismycins biosynthesis.
Chin.J.Chem., 38, 2020
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6LXK
 | | Crystal structure of Z2B3 D102R Fab in complex with influenza virus neuraminidase from A/Serbia/NS-601/2014 (H1N1) | | 分子名称: | CALCIUM ION, Heavy chain of Z2B3-D102R Fab, Light chain of Z2B3-D102R Fab, ... | | 著者 | Jiang, H, Peng, W, Qi, J, Chai, Y, Song, H, Shi, Y, Gao, G.F, Wu, Y. | | 登録日 | 2020-02-11 | | 公開日 | 2020-12-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.608 Å) | | 主引用文献 | Structure-Based Modification of an Anti-neuraminidase Human Antibody Restores Protection Efficacy against the Drifted Influenza Virus.
Mbio, 11, 2020
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6M0S
 | | 3.6A Yeast Vo state3 prime | | 分子名称: | Uncharacterized protein YPR170W-B, V-type proton ATPase subunit a, vacuolar isoform, ... | | 著者 | Roh, S.H, Shekhar, M, Pintilie, G, Chipot, C, Wilkens, S, SIngharoy, A, Chiu, W. | | 登録日 | 2020-02-22 | | 公開日 | 2020-11-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-EM and MD infer water-mediated proton transport and autoinhibition mechanisms of V o complex.
Sci Adv, 6, 2020
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6M49
 | | cryo-EM structure of Scap/Insig complex in the present of 25-hydroxyl cholesterol. | | 分子名称: | 25-HYDROXYCHOLESTEROL, Insulin-induced gene 2 protein, Sterol regulatory element-binding protein cleavage-activating protein,Sterol regulatory element-binding protein cleavage-activating protein | | 著者 | Yan, R, Cao, P, Song, W, Qian, H, Du, X, Coates, H.W, Zhao, X, Li, Y, Gao, S, Gong, X, Liu, X, Sui, J, Lei, J, Yang, H, Brown, A.J, Zhou, Q, Yan, C, Yan, N. | | 登録日 | 2020-03-06 | | 公開日 | 2021-01-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols.
Science, 371, 2021
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1AHJ
 | | NITRILE HYDRATASE | | 分子名称: | FE (III) ION, NITRILE HYDRATASE (SUBUNIT ALPHA), NITRILE HYDRATASE (SUBUNIT BETA) | | 著者 | Huang, W, Schneider, G, Lindqvist, Y. | | 登録日 | 1997-04-05 | | 公開日 | 1998-04-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Crystal structure of nitrile hydratase reveals a novel iron centre in a novel fold.
Structure, 5, 1997
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5BOX
 | | Structure of TrmBL2, an archaeal chromatin protein, shows a novel mode of DNA binding. | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (25-MER), DNA TGM (25-MER), ... | | 著者 | Ahmad, M.U, Diederichs, K, Welte, W. | | 登録日 | 2015-05-27 | | 公開日 | 2015-09-02 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural Insights into Nonspecific Binding of DNA by TrmBL2, an Archaeal Chromatin Protein.
J.Mol.Biol., 427, 2015
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6M7V
 | | Human DNA polymerase eta extension complex with cdA at the -1 position | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(P*(02I)P*CP*TP*CP*AP*CP*AP*CP*T)-3'), DNA (5'-D(P*GP*TP*GP*TP*GP*AP*GP*T)-3'), ... | | 著者 | Weng, P, Gao, Y, Yang, W. | | 登録日 | 2018-08-21 | | 公開日 | 2018-09-12 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.062 Å) | | 主引用文献 | Bypassing a 8,5'-cyclo-2'-deoxyadenosine lesion by human DNA polymerase eta at atomic resolution.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6LQI
 | | Cryo-EM structure of the mouse Piezo1 isoform Piezo1.1 | | 分子名称: | Piezo-type mechanosensitive ion channel component 1 | | 著者 | Geng, J, Liu, W, Zhou, H, Zhang, T, Wang, L, Zhang, M, Shen, B, Li, X, Xiao, B. | | 登録日 | 2020-01-13 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | A Plug-and-Latch Mechanism for Gating the Mechanosensitive Piezo Channel.
Neuron, 106, 2020
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6LK7
 | | crystal structure of Os1348 from Pseudomonas sp. Os17 | | 分子名称: | Nitrile hydratase, alpha chain | | 著者 | Takeuchi, K, Tsuchiya, W, Fujimoto, Z, Yamada, K, Someya, N, Yamazaki, T. | | 登録日 | 2019-12-18 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.903 Å) | | 主引用文献 | Discovery of an Antibiotic-Related Small Protein of Biocontrol Strain Pseudomonas sp. Os17 by a Genome-Mining Strategy.
Front Microbiol, 11, 2020
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6LMU
 | | Cryo-EM structure of the human CALHM2 | | 分子名称: | Calcium homeostasis modulator protein 2 | | 著者 | Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O. | | 登録日 | 2019-12-26 | | 公開日 | 2020-07-29 | | 最終更新日 | 2020-09-09 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies.
Sci Adv, 6, 2020
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6LPB
 | | Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Kobayashi, K, Shihoya, W, Nishizawa, T, Nureki, O. | | 登録日 | 2020-01-09 | | 公開日 | 2020-03-11 | | 最終更新日 | 2020-03-25 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein.
Nat.Struct.Mol.Biol., 27, 2020
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5BMS
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