6M7V

Human DNA polymerase eta extension complex with cdA at the -1 position

Summary for 6M7V

• Entry DOI: 10.2210/pdb6m7v/pdb
• Descriptor: DNA polymerase eta, DNA (5'-D(P*GP*TP*GP*TP*GP*AP*GP*T)-3'), DNA (5'-D(P*(02I)P*CP*TP*CP*AP*CP*AP*CP*T)-3'), ... (7 entities in total)
• Functional Keywords: translesion synthesis, human dna polymerse eta cda, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 54431.88

Authors

Weng, P.,Gao, Y.,Yang, W. (deposition date: 2018-08-21, release date: 2018-09-12, Last modification date: 2023-10-11)

• Primary citation: Weng, P.J.,Gao, Y.,Gregory, M.T.,Wang, P.,Wang, Y.,Yang, W.; Bypassing a 8,5'-cyclo-2'-deoxyadenosine lesion by human DNA polymerase eta at atomic resolution.; Proc. Natl. Acad. Sci. U.S.A., 115:10660-10665, 2018; PubMed: 30275308; DOI: 10.1073/pnas.1812856115

Experimental method

X-RAY DIFFRACTION (3.062 Å)